BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 33715230)

  • 1. ATM inhibitor KU-55933 induces apoptosis and inhibits motility by blocking GLUT1-mediated glucose uptake in aggressive cancer cells with sustained activation of Akt.
    Harris BRE; Zhang Y; Tao J; Shen R; Zhao X; Cleary MP; Wang T; Yang DQ
    FASEB J; 2021 Apr; 35(4):e21264. PubMed ID: 33715230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
    Li Y; Yang DQ
    Mol Cancer Ther; 2010 Jan; 9(1):113-25. PubMed ID: 20053781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.
    Golding SE; Rosenberg E; Valerie N; Hussaini I; Frigerio M; Cockcroft XF; Chong WY; Hummersone M; Rigoreau L; Menear KA; O'Connor MJ; Povirk LF; van Meter T; Valerie K
    Mol Cancer Ther; 2009 Oct; 8(10):2894-902. PubMed ID: 19808981
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidized ATM-mediated glycolysis enhancement in breast cancer-associated fibroblasts contributes to tumor invasion through lactate as metabolic coupling.
    Sun K; Tang S; Hou Y; Xi L; Chen Y; Yin J; Peng M; Zhao M; Cui X; Liu M
    EBioMedicine; 2019 Mar; 41():370-383. PubMed ID: 30799198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of ataxia-telangiectasia mutated (ATM) in porcine oocyte in vitro maturation.
    Lin ZL; Kim NH
    Cell Biol Int; 2015 Jun; 39(6):710-20. PubMed ID: 25598069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells.
    Halaby MJ; Hibma JC; He J; Yang DQ
    Cell Signal; 2008 Aug; 20(8):1555-63. PubMed ID: 18534819
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of triple‑negative breast cancer proliferation and motility by reactivating p53 and inhibiting overactivated Akt.
    Cao W; Shen R; Richard S; Liu Y; Jalalirad M; Cleary MP; D'Assoro AB; Gradilone SA; Yang DQ
    Oncol Rep; 2022 Feb; 47(2):. PubMed ID: 34958116
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phenformin and ataxia-telangiectasia mutated inhibitors synergistically co-suppress liver cancer cell growth by damaging mitochondria.
    Wu T; Zhou S; Qin M; Tang J; Yan X; Huang L; Huang M; Deng J; Xiao D; Hu X; Wu J; Yang X; Li G
    FEBS Open Bio; 2021 May; 11(5):1440-1451. PubMed ID: 33742560
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells.
    Hong R; Ma F; Zhang W; Yu X; Li Q; Luo Y; Zhu C; Jiang W; Xu B
    BMC Cancer; 2016 Sep; 16(1):725. PubMed ID: 27613518
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alterations in cellular energy metabolism associated with the antiproliferative effects of the ATM inhibitor KU-55933 and with metformin.
    Zakikhani M; Bazile M; Hashemi S; Javeshghani S; Avizonis D; St Pierre J; Pollak MN
    PLoS One; 2012; 7(11):e49513. PubMed ID: 23185347
    [TBL] [Abstract][Full Text] [Related]  

  • 11. miRNA-451 inhibits glioma cell proliferation and invasion by downregulating glucose transporter 1.
    Guo H; Nan Y; Zhen Y; Zhang Y; Guo L; Yu K; Huang Q; Zhong Y
    Tumour Biol; 2016 Oct; 37(10):13751-13761. PubMed ID: 27476171
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D.
    Chwastek J; Jantas D; Lasoń W
    Int J Biochem Cell Biol; 2017 Jun; 87():38-53. PubMed ID: 28341201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin 6-triggered ataxia-telangiectasia mutated kinase activation facilitates epithelial-to-mesenchymal transition in lung cancer by upregulating vimentin expression.
    Jiang YN; Ni XY; Yan HQ; Shi L; Lu NN; Wang YN; Li Q; Gao FG
    Exp Cell Res; 2019 Aug; 381(2):165-171. PubMed ID: 31100307
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different Regulation of Glut1 Expression and Glucose Uptake during the Induction and Chronic Stages of TGFβ1-Induced EMT in Breast Cancer Cells.
    Nilchian A; Giotopoulou N; Sun W; Fuxe J
    Biomolecules; 2020 Dec; 10(12):. PubMed ID: 33271824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATM and GLUT1-S490 phosphorylation regulate GLUT1 mediated transport in skeletal muscle.
    Andrisse S; Patel GD; Chen JE; Webber AM; Spears LD; Koehler RM; Robinson-Hill RM; Ching JK; Jeong I; Fisher JS
    PLoS One; 2013; 8(6):e66027. PubMed ID: 23776597
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells.
    Yang Y; Wolfram J; Boom K; Fang X; Shen H; Ferrari M
    Cell Biochem Funct; 2013 Jul; 31(5):374-9. PubMed ID: 23042260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.
    Wellberg EA; Johnson S; Finlay-Schultz J; Lewis AS; Terrell KL; Sartorius CA; Abel ED; Muller WJ; Anderson SM
    Breast Cancer Res; 2016 Dec; 18(1):131. PubMed ID: 27998284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced expression of glucose transporter-1 in vascular smooth muscle cells via the Akt/tuberous sclerosis complex subunit 2 (TSC2)/mammalian target of rapamycin (mTOR)/ribosomal S6 protein kinase (S6K) pathway in experimental renal failure.
    Lin CY; Hsu SC; Lee HS; Lin SH; Tsai CS; Huang SM; Shih CC; Hsu YJ
    J Vasc Surg; 2013 Feb; 57(2):475-85. PubMed ID: 23265586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake.
    Beg M; Abdullah N; Thowfeik FS; Altorki NK; McGraw TE
    Elife; 2017 Jun; 6():. PubMed ID: 28589878
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism.
    Chen GQ; Tang CF; Shi XK; Lin CY; Fatima S; Pan XH; Yang DJ; Zhang G; Lu AP; Lin SH; Bian ZX
    Oncotarget; 2015 Sep; 6(27):24148-62. PubMed ID: 26160839
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.