BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 33719007)

  • 1. Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects.
    Rendic SP
    Arch Toxicol; 2021 May; 95(5):1535-1546. PubMed ID: 33719007
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic polymorphisms in MDR1, CYP3A4 and CYP3A5 genes in a Ghanaian population: a plausible explanation for altered metabolism of ivermectin in humans?
    Kudzi W; Dodoo AN; Mills JJ
    BMC Med Genet; 2010 Jul; 11():111. PubMed ID: 20630055
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of the Potential for Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions for Cilofexor, a Selective Nonsteroidal Farnesoid X Receptor (FXR) Agonist.
    Younis I; Weber E; Nelson C; Kirby BJ; Shen G; Xiao D; Watkins TR; Othman AA
    Clin Pharmacokinet; 2023 Apr; 62(4):609-621. PubMed ID: 36906733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Islatravir Is Not Expected to Be a Victim or Perpetrator of Drug-Drug Interactions via Major Drug-Metabolizing Enzymes or Transporters.
    Bleasby K; Houle R; Hafey M; Lin M; Guo J; Lu B; Sanchez RI; Fillgrove KL
    Viruses; 2021 Aug; 13(8):. PubMed ID: 34452431
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor.
    Zhang H; Ou YC; Su D; Wang F; Wang L; Sahasranaman S; Tang Z
    Pharmacol Res Perspect; 2021 Dec; 9(6):e00870. PubMed ID: 34664792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. No evidence for interactions of dimethylfumarate (DMF) and its main metabolite monomethylfumarate (MMF) with human cytochrome P450 (CYP) enzymes and the P-glycoprotein (P-gp) drug transporter.
    Aubets J; Jansat JM; Salva M; Birks VM; Cole RJ; Lewis J; Pitcher A; Hall M
    Pharmacol Res Perspect; 2019 Dec; 7(6):e00540. PubMed ID: 31832203
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the metabolites of ivermectin in humans.
    Tipthara P; Kobylinski KC; Godejohann M; Hanboonkunupakarn B; Roth A; Adams JH; White NJ; Jittamala P; Day NPJ; Tarning J
    Pharmacol Res Perspect; 2021 Feb; 9(1):e00712. PubMed ID: 33497030
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes.
    Rendic SP; Guengerich FP
    Arch Toxicol; 2024 Jun; 98(6):1581-1628. PubMed ID: 38520539
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug-Drug Interaction Studies.
    Elmeliegy M; Vourvahis M; Guo C; Wang DD
    Clin Pharmacokinet; 2020 Jun; 59(6):699-714. PubMed ID: 32052379
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies.
    Qiu JX; Zhou ZW; He ZX; Zhang X; Zhou SF; Zhu S
    Drug Des Devel Ther; 2015; 9():841-66. PubMed ID: 25733806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP).
    Rigalli JP; Gagliardi A; Diester K; Bajraktari-Sylejmani G; Blank A; Burhenne J; Lenard A; Werntz L; Huppertz A; Münch L; Wendt JM; Sauter M; Haefeli WE; Weiss J
    Int J Mol Sci; 2024 Apr; 25(7):. PubMed ID: 38612927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drugs That Interact With Colchicine Via Inhibition of Cytochrome P450 3A4 and P-Glycoprotein: A Signal Detection Analysis Using a Database of Spontaneously Reported Adverse Events (FAERS).
    Gómez-Lumbreras A; Boyce RD; Villa-Zapata L; Tan MS; Hansten PD; Horn J; Malone DC
    Ann Pharmacother; 2023 Oct; 57(10):1137-1146. PubMed ID: 36688283
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.
    Matthaei J; Tzvetkov MV; Gal V; Sachse-Seeboth C; Sehrt D; Hjelmborg JB; Hofmann U; Schwab M; Kerb R; Brockmöller J
    Genome Med; 2016 Nov; 8(1):119. PubMed ID: 27825374
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of the Herb-Drug Interaction (HDI) Potential of
    Husain I; Dale OR; Idrisi M; Gurley BJ; Avula B; Katragunta K; Ali Z; Chittiboyina A; Noonan G; Khan IA; Khan SI
    J Agric Food Chem; 2023 May; 71(19):7521-7534. PubMed ID: 37134183
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain barrier.
    Colón Ortiz R; Knerler S; Fridman LB; Mercado A; Price AS; Rosado-Franco JJ; Wilkins H; Flores BR; Orsburn BC; Williams DW
    Fluids Barriers CNS; 2024 Jan; 21(1):5. PubMed ID: 38200564
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Cytochrome P450 2C9 in COVID-19 Treatment: Current Status and Future Directions.
    Lim SYM; Al Bishtawi B; Lim W
    Eur J Drug Metab Pharmacokinet; 2023 May; 48(3):221-240. PubMed ID: 37093458
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the Abcg2 Transporter in Secretion into Milk of the Anthelmintic Clorsulon: Interaction with Ivermectin.
    Blanco-Paniagua E; Álvarez-Fernández L; Rodríguez-Alonso A; Millán-Garcia A; Álvarez AI; Merino G
    Antimicrob Agents Chemother; 2023 May; 67(5):e0009523. PubMed ID: 37078871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tazemetostat synergistically combats multidrug resistance by the unique triple inhibition of ABCB1, ABCC1, and ABCG2 efflux transporters in vitro and ex vivo.
    Budagaga Y; Sabet Z; Zhang Y; Novotná E; Hanke I; Rozkoš T; Hofman J
    Biochem Pharmacol; 2023 Oct; 216():115769. PubMed ID: 37634597
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Importance of multi-p450 inhibition in drug-drug interactions: evaluation of incidence, inhibition magnitude, and prediction from in vitro data.
    Isoherranen N; Lutz JD; Chung SP; Hachad H; Levy RH; Ragueneau-Majlessi I
    Chem Res Toxicol; 2012 Nov; 25(11):2285-300. PubMed ID: 22823924
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions.
    Xiang Z; Guan H; Zhao X; Xie Q; Xie Z; Cai F; Dang R; Li M; Wang C
    Food Res Int; 2024 Mar; 180():114068. PubMed ID: 38395544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.