These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 33724516)

  • 1. Steatotic Hepatocytes Release Mature VLDL Through Methionine and Tyrosine Metabolism in a Keap1-Nrf2-Dependent Manner.
    Sano A; Kakazu E; Hamada S; Inoue J; Ninomiya M; Iwata T; Tsuruoka M; Sato K; Masamune A
    Hepatology; 2021 Sep; 74(3):1271-1286. PubMed ID: 33724516
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hepatocyte-specific Keap1 deletion reduces liver steatosis but not inflammation during non-alcoholic steatohepatitis development.
    Ramadori P; Drescher H; Erschfeld S; Schumacher F; Berger C; Fragoulis A; Schenkel J; Kensler TW; Wruck CJ; Trautwein C; Kroy DC; Streetz KL
    Free Radic Biol Med; 2016 Feb; 91():114-26. PubMed ID: 26698665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydrogen Sulfide Alleviates Liver Injury Through the S-Sulfhydrated-Kelch-Like ECH-Associated Protein 1/Nuclear Erythroid 2-Related Factor 2/Low-Density Lipoprotein Receptor-Related Protein 1 Pathway.
    Zhao S; Song T; Gu Y; Zhang Y; Cao S; Miao Q; Zhang X; Chen H; Gao Y; Zhang L; Han Y; Wang H; Pu J; Xie L; Ji Y
    Hepatology; 2021 Jan; 73(1):282-302. PubMed ID: 32219872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of GCN2 alleviates hepatic steatosis and oxidative stress in obese mice: Involvement of NRF2 regulation.
    Yuan J; Yu Z; Gao J; Luo K; Shen X; Cui B; Lu Z
    Redox Biol; 2022 Feb; 49():102224. PubMed ID: 34954499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis.
    Mohs A; Otto T; Schneider KM; Peltzer M; Boekschoten M; Holland CH; Hudert CA; Kalveram L; Wiegand S; Saez-Rodriguez J; Longerich T; Hengstler JG; Trautwein C
    J Hepatol; 2021 Mar; 74(3):638-648. PubMed ID: 33342543
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity.
    Lee DH; Park JS; Lee YS; Han J; Lee DK; Kwon SW; Han DH; Lee YH; Bae SH
    Autophagy; 2020 Nov; 16(11):1949-1973. PubMed ID: 31913745
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Punicalagin attenuates palmitate-induced lipotoxicity in HepG2 cells by activating the Keap1-Nrf2 antioxidant defense system.
    Yan C; Sun W; Wang X; Long J; Liu X; Feng Z; Liu J
    Mol Nutr Food Res; 2016 May; 60(5):1139-49. PubMed ID: 26989875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
    Unni S; Deshmukh P; Krishnappa G; Kommu P; Padmanabhan B
    FEBS J; 2021 Mar; 288(5):1599-1613. PubMed ID: 32672401
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Processed Meat Protein Promoted Inflammation and Hepatic Lipogenesis by Upregulating Nrf2/Keap1 Signaling Pathway in Glrx-Deficient Mice.
    Ahmad MI; Zou X; Ijaz MU; Hussain M; Liu C; Xu X; Zhou G; Li C
    J Agric Food Chem; 2019 Aug; 67(32):8794-8809. PubMed ID: 31345023
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts.
    Eswaran S; Babbar A; Drescher HK; Hitch TCA; Clavel T; Muschaweck M; Ritz T; Kroy DC; Trautwein C; Wagner N; Schippers A
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet.
    Zhang YK; Yeager RL; Tanaka Y; Klaassen CD
    Toxicol Appl Pharmacol; 2010 Jun; 245(3):326-34. PubMed ID: 20350562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.
    Xu J; Kulkarni SR; Donepudi AC; More VR; Slitt AL
    Diabetes; 2012 Dec; 61(12):3208-18. PubMed ID: 22936178
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor.
    Taguchi K; Masui S; Itoh T; Miyajima A; Yamamoto M
    Toxicol Sci; 2019 Jan; 167(1):227-238. PubMed ID: 30215777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis.
    Okada K; Warabi E; Sugimoto H; Horie M; Tokushige K; Ueda T; Harada N; Taguchi K; Hashimoto E; Itoh K; Ishii T; Utsunomiya H; Yamamoto M; Shoda J
    J Gastroenterol; 2012 Aug; 47(8):924-35. PubMed ID: 22367278
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis.
    Lee DH; Han DH; Nam KT; Park JS; Kim SH; Lee M; Kim G; Min BS; Cha BS; Lee YS; Sung SH; Jeong H; Ji HW; Lee MJ; Lee JS; Lee HY; Chun Y; Kim J; Komatsu M; Lee YH; Bae SH
    Free Radic Biol Med; 2016 Oct; 99():520-532. PubMed ID: 27634173
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo.
    Park SY; Gurung R; Hwang JH; Kang JH; Jung HJ; Zeb A; Hwang JI; Park SJ; Maeng HJ; Shin D; Oh SH
    Redox Biol; 2023 Aug; 64():102783. PubMed ID: 37348157
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPAR
    Tao S; Yang Y; Li J; Wang H; Ma Y
    Oxid Med Cell Longev; 2021; 2021():6610124. PubMed ID: 33603948
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease.
    Liu P; Anandhan A; Chen J; Shakya A; Dodson M; Ooi A; Chapman E; White E; Garcia JG; Zhang DD
    Redox Biol; 2023 Feb; 59():102570. PubMed ID: 36495698
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dimethyl fumarate and monoethyl fumarate exhibit differential effects on KEAP1, NRF2 activation, and glutathione depletion in vitro.
    Brennan MS; Matos MF; Li B; Hronowski X; Gao B; Juhasz P; Rhodes KJ; Scannevin RH
    PLoS One; 2015; 10(3):e0120254. PubMed ID: 25793262
    [TBL] [Abstract][Full Text] [Related]  

  • 20. tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation.
    Li S; Li J; Shen C; Zhang X; Sun S; Cho M; Sun C; Song Z
    Biochim Biophys Acta; 2014 Jan; 1841(1):22-33. PubMed ID: 24055888
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.