197 related articles for article (PubMed ID: 33725632)
21. Synthesis of novel forskolin isoxazole derivatives with potent anti-cancer activity against breast cancer cell lines.
Burra S; Voora V; Rao CP; Vijay Kumar P; Kancha RK; David Krupadanam GL
Bioorg Med Chem Lett; 2017 Sep; 27(18):4314-4318. PubMed ID: 28838692
[TBL] [Abstract][Full Text] [Related]
22. Fe
Maddela S; Makula A; Galigniana MD; Parambi DGT; Federicci F; Mazaira G; Hendawy OM; Dev S; Mathew GE; Mathew B
Arch Pharm (Weinheim); 2019 Jan; 352(1):e1800174. PubMed ID: 30485473
[TBL] [Abstract][Full Text] [Related]
23. Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines.
Monteiro Â; Gonçalves LM; Santos MM
Eur J Med Chem; 2014 May; 79():266-72. PubMed ID: 24747063
[TBL] [Abstract][Full Text] [Related]
24. Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.
Qin JJ; Wang W; Voruganti S; Wang H; Zhang WD; Zhang R
Oncotarget; 2015 Feb; 6(5):2623-40. PubMed ID: 25739118
[TBL] [Abstract][Full Text] [Related]
25. Design, synthesis and biological evaluation of novel pyrrolidone-based derivatives as potent p53-MDM2 inhibitors.
Si D; Luo H; Zhang X; Yang K; Wen H; Li W; Liu J
Bioorg Chem; 2021 Oct; 115():105268. PubMed ID: 34426149
[TBL] [Abstract][Full Text] [Related]
26. Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking.
Lotfy G; Said MM; El Ashry ESH; El Tamany ESH; Al-Dhfyan A; Abdel Aziz YM; Barakat A
Bioorg Med Chem; 2017 Feb; 25(4):1514-1523. PubMed ID: 28126436
[TBL] [Abstract][Full Text] [Related]
27. Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.
Ding K; Lu Y; Nikolovska-Coleska Z; Wang G; Qiu S; Shangary S; Gao W; Qin D; Stuckey J; Krajewski K; Roller PP; Wang S
J Med Chem; 2006 Jun; 49(12):3432-5. PubMed ID: 16759082
[TBL] [Abstract][Full Text] [Related]
28. Targeted Synthesis of Complex Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2-p53 Inhibitors.
Gollner A; Weinstabl H; Fuchs JE; Rudolph D; Garavel G; Hofbauer KS; Karolyi-Oezguer J; Gmaschitz G; Hela W; Kerres N; Grondal E; Werni P; Ramharter J; Broeker J; McConnell DB
ChemMedChem; 2019 Jan; 14(1):88-93. PubMed ID: 30458062
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis and biological evaluation of novel antitumor spirodihydrothiopyran-oxindole derivatives.
Liu W; Chen S; Zhang F; He S; Wang S; Sheng C
Bioorg Med Chem Lett; 2019 Jul; 29(13):1636-1642. PubMed ID: 31047751
[TBL] [Abstract][Full Text] [Related]
30. Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.
Rodriguez KX; Howe EN; Bacher EP; Burnette M; Meloche JL; Meisel J; Schnepp P; Tan X; Chang M; Zartman J; Zhang S; Ashfeld BL
ChemMedChem; 2019 Sep; 14(18):1653-1661. PubMed ID: 31140738
[TBL] [Abstract][Full Text] [Related]
31. Regio- and stereoselective synthesis of new spirooxindoles via 1,3-dipolar cycloaddition reaction: Anticancer and molecular docking studies.
Lotfy G; El Ashry ESH; Said MM; El Tamany ES; Abdel Aziz YM; Al-Dhfyan A; Al-Majid AM; Barakat A
J Photochem Photobiol B; 2018 Mar; 180():98-108. PubMed ID: 29413708
[TBL] [Abstract][Full Text] [Related]
32. Design, synthesis, and biological evaluation of furan-bearing pyrazolo[3,4-b]pyridines as novel inhibitors of CDK2 and P53-MDM2 protein-protein interaction.
Ezzat MAF; Elmasry GF; El-Mageed MMAA; Fouad MA; Abdel-Aziz HA; Elewa SI
Drug Dev Res; 2023 Sep; 84(6):1183-1203. PubMed ID: 37191966
[TBL] [Abstract][Full Text] [Related]
33. Synthesis, Biological Evaluation and In Silico Studies of Certain Oxindole-Indole Conjugates as Anticancer CDK Inhibitors.
Al-Warhi T; El Kerdawy AM; Aljaeed N; Ismael OE; Ayyad RR; Eldehna WM; Abdel-Aziz HA; Al-Ansary GH
Molecules; 2020 Apr; 25(9):. PubMed ID: 32349307
[TBL] [Abstract][Full Text] [Related]
34. Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 2.
Wang W; Lv D; Qiu N; Zhang L; Hu C; Hu Y
Bioorg Med Chem; 2013 Jun; 21(11):2886-94. PubMed ID: 23611770
[TBL] [Abstract][Full Text] [Related]
35. Design, synthesis and biological evaluation of novel steroidal spiro-oxindoles as potent antiproliferative agents.
Yu B; Shi XJ; Qi PP; Yu DQ; Liu HM
J Steroid Biochem Mol Biol; 2014 May; 141():121-34. PubMed ID: 24508598
[TBL] [Abstract][Full Text] [Related]
36. Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 Interaction.
Gollner A; Rudolph D; Arnhof H; Bauer M; Blake SM; Boehmelt G; Cockroft XL; Dahmann G; Ettmayer P; Gerstberger T; Karolyi-Oezguer J; Kessler D; Kofink C; Ramharter J; Rinnenthal J; Savchenko A; Schnitzer R; Weinstabl H; Weyer-Czernilofsky U; Wunberg T; McConnell DB
J Med Chem; 2016 Nov; 59(22):10147-10162. PubMed ID: 27775892
[TBL] [Abstract][Full Text] [Related]
37. Stereocontrolled [3+2] Cycloaddition of Donor-Acceptor Cyclopropanes to Iminooxindoles: Access to Spiro[oxindole-3,2'-pyrrolidines].
Akaev AA; Bezzubov SI; Desyatkin VG; Vorobyeva NS; Majouga AG; Melnikov MY; Budynina EM
J Org Chem; 2019 Mar; 84(6):3340-3356. PubMed ID: 30735387
[TBL] [Abstract][Full Text] [Related]
38. Antiproliferative novel isoxazoles: modeling, virtual screening, synthesis, and bioactivity evaluation.
Tzanetou E; Liekens S; Kasiotis KM; Melagraki G; Afantitis A; Fokialakis N; Haroutounian SA
Eur J Med Chem; 2014 Jun; 81():139-49. PubMed ID: 24836066
[TBL] [Abstract][Full Text] [Related]
39. 1,3-Dipolar Cycloaddition Reactions for the Synthesis of Novel Oxindole Derivatives and Their Cytotoxic Properties.
Mali PR; Shirsat PK; Khomane N; Nayak L; Nanubolu JB; Meshram HM
ACS Comb Sci; 2017 Oct; 19(10):633-639. PubMed ID: 28816439
[TBL] [Abstract][Full Text] [Related]
40. Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity.
Al-Rashood ST; Hamed AR; Hassan GS; Alkahtani HM; Almehizia AA; Alharbi A; Al-Sanea MM; Eldehna WM
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):831-839. PubMed ID: 32208781
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
