150 related articles for article (PubMed ID: 33725656)
1. One-step modification to identify dual-inhibitors targeting both pancreatic triglyceride lipase and Niemann-Pick C1-like 1.
Zhang R; Song Z; Wang X; Xue J; Xing D
Eur J Med Chem; 2021 Apr; 216():113358. PubMed ID: 33725656
[TBL] [Abstract][Full Text] [Related]
2. First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor.
Liu W; Liang B; Zeng J; Meng J; Shi L; Yang S; Chang J; Wang C; Hu X; Wang X; Han N; Lu C; Li J; Wang C; Li H; Zhang R; Xing D
Molecules; 2022 Sep; 27(19):. PubMed ID: 36234807
[TBL] [Abstract][Full Text] [Related]
3. Novel application potential of cinaciguat in the treatment of mixed hyperlipidemia through targeting PTL/NPC1L1 and alleviating intestinal microbiota dysbiosis and metabolic disorders.
Jia A; Jiang H; Liu W; Chen P; Xu Q; Zhang R; Sun J
Pharmacol Res; 2023 Aug; 194():106854. PubMed ID: 37460003
[TBL] [Abstract][Full Text] [Related]
4. Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption.
Zhang R; Liu W; Zeng J; Meng J; Jiang H; Wang J; Xing D
Eur J Med Chem; 2022 Feb; 230():114111. PubMed ID: 35063734
[TBL] [Abstract][Full Text] [Related]
5. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).
Garcia-Calvo M; Lisnock J; Bull HG; Hawes BE; Burnett DA; Braun MP; Crona JH; Davis HR; Dean DC; Detmers PA; Graziano MP; Hughes M; Macintyre DE; Ogawa A; O'neill KA; Iyer SP; Shevell DE; Smith MM; Tang YS; Makarewicz AM; Ujjainwalla F; Altmann SW; Chapman KT; Thornberry NA
Proc Natl Acad Sci U S A; 2005 Jun; 102(23):8132-7. PubMed ID: 15928087
[TBL] [Abstract][Full Text] [Related]
6. The Effect of Polyphenols on Hypercholesterolemia through Inhibiting the Transport and Expression of Niemann-Pick C1-Like 1.
Kobayashi S
Int J Mol Sci; 2019 Oct; 20(19):. PubMed ID: 31590417
[TBL] [Abstract][Full Text] [Related]
7. Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study.
Kwon RJ; Park EJ; Lee SY; Lee Y; Hwang C; Kim C; Cho YH
Lipids Health Dis; 2021 Sep; 20(1):104. PubMed ID: 34511128
[TBL] [Abstract][Full Text] [Related]
8. N-terminal domain of the cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) is essential for α-tocopherol transport.
Kamishikiryo J; Haraguchi M; Nakashima S; Tasaka Y; Narahara H; Sugihara N; Nakamura T; Morita T
Biochem Biophys Res Commun; 2017 Apr; 486(2):476-480. PubMed ID: 28315682
[TBL] [Abstract][Full Text] [Related]
9. In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs.
Hawes BE; O'neill KA; Yao X; Crona JH; Davis HR; Graziano MP; Altmann SW
Mol Pharmacol; 2007 Jan; 71(1):19-29. PubMed ID: 17005902
[TBL] [Abstract][Full Text] [Related]
10. Zetia: inhibition of Niemann-Pick C1 Like 1 (NPC1L1) to reduce intestinal cholesterol absorption and treat hyperlipidemia.
Davis HR; Veltri EP
J Atheroscler Thromb; 2007 Jun; 14(3):99-108. PubMed ID: 17587760
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Niemann-Pick C1-Like 1 by Ezetimibe Reduces Dietary 5β,6β-Epoxycholesterol Absorption in Rats.
Shirouchi B; Furukawa Y; Nakamura Y; Kawauchi A; Imaizumi K; Oku H; Sato M
Cardiovasc Drugs Ther; 2019 Feb; 33(1):35-44. PubMed ID: 30671747
[TBL] [Abstract][Full Text] [Related]
12. Inhibitory Effect of Isoliquiritigenin in Niemann-Pick C1-Like 1-Mediated Cholesterol Uptake.
Zeng J; Liu W; Liang B; Shi L; Yang S; Meng J; Chang J; Hu X; Zhang R; Xing D
Molecules; 2022 Nov; 27(21):. PubMed ID: 36364321
[TBL] [Abstract][Full Text] [Related]
13. Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.
Labonté ED; Howles PN; Granholm NA; Rojas JC; Davies JP; Ioannou YA; Hui DY
Biochim Biophys Acta; 2007 Sep; 1771(9):1132-9. PubMed ID: 17442616
[TBL] [Abstract][Full Text] [Related]
14. Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
Knöpfel M; Davies JP; Duong PT; Kvaernø L; Carreira EM; Phillips MC; Ioannou YA; Hauser H
Biochim Biophys Acta; 2007 Sep; 1771(9):1140-7. PubMed ID: 17689140
[TBL] [Abstract][Full Text] [Related]
15. Lipid-lowering effects of Coffea arabica pulp aqueous extract in Caco-2 cells and hypercholesterolemic rats.
Ontawong A; Duangjai A; Muanprasat C; Pasachan T; Pongchaidecha A; Amornlerdpison D; Srimaroeng C
Phytomedicine; 2019 Jan; 52():187-197. PubMed ID: 30599898
[TBL] [Abstract][Full Text] [Related]
16. Niemann-pick C1-like 1 mediates alpha-tocopherol transport.
Narushima K; Takada T; Yamanashi Y; Suzuki H
Mol Pharmacol; 2008 Jul; 74(1):42-9. PubMed ID: 18403720
[TBL] [Abstract][Full Text] [Related]
17. Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment.
Yoshida M
Curr Vasc Pharmacol; 2011 Jan; 9(1):121-3. PubMed ID: 21044016
[TBL] [Abstract][Full Text] [Related]
18. Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.
Yamanashi Y; Takada T; Suzuki H
J Pharmacol Exp Ther; 2007 Feb; 320(2):559-64. PubMed ID: 17135346
[TBL] [Abstract][Full Text] [Related]
19. Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice.
Yamamoto H; Yamanashi Y; Takada T; Mu S; Tanaka Y; Komine T; Suzuki H
Mol Pharmacol; 2019 Jul; 96(1):47-55. PubMed ID: 31064810
[TBL] [Abstract][Full Text] [Related]
20. Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Saha P; Shumate JL; Caldwell JG; Elghobashi-Meinhardt N; Lu A; Zhang L; Olsson NE; Elias JE; Pfeffer SR
Elife; 2020 May; 9():. PubMed ID: 32410728
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
