These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 33730996)

  • 1. Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor.
    Bartoszewska S; Króliczewski J; Crossman DK; Pogorzelska A; Bagiński M; Collawn JF; Bartoszewski R
    Cell Mol Biol Lett; 2021 Mar; 26(1):11. PubMed ID: 33730996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N; Fulciniti M; Gorgun G; Tai YT; Cirstea D; Santo L; Hu Y; Fabre C; Minami J; Ohguchi H; Kiziltepe T; Ikeda H; Kawano Y; French M; Blumenthal M; Tam V; Kertesz NL; Malyankar UM; Hokenson M; Pham T; Zeng Q; Patterson JB; Richardson PG; Munshi NC; Anderson KC
    Blood; 2012 Jun; 119(24):5772-81. PubMed ID: 22538852
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras.
    Blazanin N; Son J; Craig-Lucas AB; John CL; Breech KJ; Podolsky MA; Glick AB
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9900-9905. PubMed ID: 28847931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome-wide mRNA profiling identifies X-box-binding protein 1 (XBP1) as an IRE1 and PUMA repressor.
    Gebert M; Sobolewska A; Bartoszewska S; Cabaj A; Crossman DK; Króliczewski J; Madanecki P; Dąbrowski M; Collawn JF; Bartoszewski R
    Cell Mol Life Sci; 2021 Nov; 78(21-22):7061-7080. PubMed ID: 34636989
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors.
    Wang L; Perera BG; Hari SB; Bhhatarai B; Backes BJ; Seeliger MA; Schürer SC; Oakes SA; Papa FR; Maly DJ
    Nat Chem Biol; 2012 Dec; 8(12):982-9. PubMed ID: 23086298
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Opposite Roles of RNase and Kinase Activities of Inositol-Requiring Enzyme 1 (IRE1) on HSV-1 Replication.
    Su A; Wang H; Li Y; Wang X; Chen D; Wu Z
    Viruses; 2017 Aug; 9(9):. PubMed ID: 28832521
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.
    Back SH; Lee K; Vink E; Kaufman RJ
    J Biol Chem; 2006 Jul; 281(27):18691-706. PubMed ID: 16644724
    [TBL] [Abstract][Full Text] [Related]  

  • 8. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment.
    Harnoss JM; Le Thomas A; Reichelt M; Guttman O; Wu TD; Marsters SA; Shemorry A; Lawrence DA; Kan D; Segal E; Merchant M; Totpal K; Crocker LM; Mesh K; Dohse M; Solon M; Modrusan Z; Rudolph J; Koeppen H; Walter P; Ashkenazi A
    Cancer Res; 2020 Jun; 80(11):2368-2379. PubMed ID: 32265225
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
    Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
    Guo FJ; Xiong Z; Lu X; Ye M; Han X; Jiang R
    Cell Signal; 2014 Feb; 26(2):332-42. PubMed ID: 24269637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells.
    Nguyen LC; Renner DM; Silva D; Yang D; Parenti NA; Medina KM; Nicolaescu V; Gula H; Drayman N; Valdespino A; Mohamed A; Dann C; Wannemo K; Robinson-Mailman L; Gonzalez A; Stock L; Cao M; Qiao Z; Moellering RE; Tay S; Randall G; Beers MF; Rosner MR; Oakes SA; Weiss SR
    mBio; 2022 Oct; 13(5):e0241522. PubMed ID: 36125275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4μ8C Inhibits Insulin Secretion Independent of IRE1α RNase Activity.
    Sato H; Shiba Y; Tsuchiya Y; Saito M; Kohno K
    Cell Struct Funct; 2017 May; 42(1):61-70. PubMed ID: 28321016
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer.
    Lin J; Liu H; Fukumoto T; Zundell J; Yan Q; Tang CA; Wu S; Zhou W; Guo D; Karakashev S; Hu CA; Sarma K; Kossenkov AV; Zhang R
    Nat Commun; 2021 Sep; 12(1):5321. PubMed ID: 34493732
    [TBL] [Abstract][Full Text] [Related]  

  • 15. XBP1-FoxO1 interaction regulates ER stress-induced autophagy in auditory cells.
    Kishino A; Hayashi K; Hidai C; Masuda T; Nomura Y; Oshima T
    Sci Rep; 2017 Jun; 7(1):4442. PubMed ID: 28667325
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.
    Tsuru A; Imai Y; Saito M; Kohno K
    Sci Rep; 2016 Apr; 6():24217. PubMed ID: 27052593
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian IRE1α dynamically and functionally coalesces with stress granules.
    Liu S; Zhang X; Yao X; Wang G; Huang S; Chen P; Tang M; Cai J; Wu Z; Zhang Y; Xu R; Liu K; He K; Wang Y; Jiang L; Wang QA; Rui L; Liu J; Liu Y
    Nat Cell Biol; 2024 Jun; 26(6):917-931. PubMed ID: 38714852
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.
    Wang FM; Galson DL; Roodman GD; Ouyang H
    Exp Hematol; 2011 Oct; 39(10):999-1006. PubMed ID: 21723843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8
    Medel B; Costoya C; Fernandez D; Pereda C; Lladser A; Sauma D; Pacheco R; Iwawaki T; Salazar-Onfray F; Osorio F
    Front Immunol; 2018; 9():3050. PubMed ID: 30687308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.