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5. TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response. Akeno N; Reece AL; Callahan M; Miller AL; Kim RG; He D; Lane A; Moulton JS; Wikenheiser-Brokamp KA Mol Cancer Ther; 2017 Dec; 16(12):2913-2926. PubMed ID: 28847987 [TBL] [Abstract][Full Text] [Related]
6. Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis. Tiwari A; Tashiro K; Dixit A; Soni A; Vogel K; Hall B; Shafqat I; Slaughter J; Param N; Le A; Saunders E; Paithane U; Garcia G; Campos AR; Zettervall J; Carlson M; Starr TK; Marahrens Y; Deshpande AJ; Commisso C; Provenzano PP; Bagchi A Gastroenterology; 2020 Nov; 159(5):1882-1897.e5. PubMed ID: 32768595 [TBL] [Abstract][Full Text] [Related]
7. MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus. Godfrey JD; Morton JP; Wilczynska A; Sansom OJ; Bushell MD Cell Death Dis; 2018 May; 9(6):644. PubMed ID: 29844410 [TBL] [Abstract][Full Text] [Related]
8. Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53(R172H). Li Z; Gonzalez CL; Wang B; Zhang Y; Mejia O; Katsonis P; Lichtarge O; Myers JN; El-Naggar AK; Caulin C J Pathol; 2016 Oct; 240(2):224-34. PubMed ID: 27447534 [TBL] [Abstract][Full Text] [Related]
10. Trp53 null and R270H mutant alleles have comparable effects in regulating invasion, metastasis, and gene expression in mouse colon tumorigenesis. Tang J; Feng Y; Kuick R; Green M; Green M; Sakamoto N; Kurosu Y; Lin J; Cho KR; Fearon ER Lab Invest; 2019 Oct; 99(10):1454-1469. PubMed ID: 31148594 [TBL] [Abstract][Full Text] [Related]
11. NRF2/HO-1 axis, BIRC5, and TP53 expression in ESCC and its correlation with clinical pathological characteristics and prognosis. Gao Y; Wan L; Li M; Wang B; Ma Y Int J Biol Markers; 2023 Dec; 38(3-4):174-184. PubMed ID: 37312528 [TBL] [Abstract][Full Text] [Related]
12. Development of mouse models of angiosarcoma driven by p53. Salter DM; Griffin M; Muir M; Teo K; Culley J; Smith JR; Gomez-Cuadrado L; Matchett K; Sims AH; Hayward L; Henderson NC; Brunton VG Dis Model Mech; 2019 Jul; 12(7):. PubMed ID: 31221668 [TBL] [Abstract][Full Text] [Related]
13. Plakoglobin restores tumor suppressor activity of p53 Alaee M; Nool K; Pasdar M Cancer Sci; 2018 Jun; 109(6):1876-1888. PubMed ID: 29660231 [TBL] [Abstract][Full Text] [Related]
14. A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1. Loizou E; Banito A; Livshits G; Ho YJ; Koche RP; Sánchez-Rivera FJ; Mayle A; Chen CC; Kinalis S; Bagger FO; Kastenhuber ER; Durham BH; Lowe SW Cancer Discov; 2019 Jul; 9(7):962-979. PubMed ID: 31068365 [TBL] [Abstract][Full Text] [Related]
15. Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity. Turrell FK; Kerr EM; Gao M; Thorpe H; Doherty GJ; Cridge J; Shorthouse D; Speed A; Samarajiwa S; Hall BA; Griffiths M; Martins CP Genes Dev; 2017 Jul; 31(13):1339-1353. PubMed ID: 28790158 [TBL] [Abstract][Full Text] [Related]
16. Comparison of effects of p53 null and gain-of-function mutations on salivary tumors in MMTV-Hras transgenic mice. Jiang D; Dumur CI; Massey HD; Ramakrishnan V; Subler MA; Windle JJ PLoS One; 2015; 10(2):e0118029. PubMed ID: 25695772 [TBL] [Abstract][Full Text] [Related]
18. miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Kasinski AL; Slack FJ Cancer Res; 2012 Nov; 72(21):5576-87. PubMed ID: 22964582 [TBL] [Abstract][Full Text] [Related]
19. Intestinal cancer progression by mutant p53 through the acquisition of invasiveness associated with complex glandular formation. Nakayama M; Sakai E; Echizen K; Yamada Y; Oshima H; Han TS; Ohki R; Fujii S; Ochiai A; Robine S; Voon DC; Tanaka T; Taketo MM; Oshima M Oncogene; 2017 Oct; 36(42):5885-5896. PubMed ID: 28628120 [TBL] [Abstract][Full Text] [Related]
20. Survivin gene expression is negatively regulated by the p53 tumor suppressor gene in non-small cell lung cancer. Nakano J; Huang CL; Liu D; Ueno M; Sumitomo S; Yokomise H Int J Oncol; 2005 Nov; 27(5):1215-21. PubMed ID: 16211215 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]