BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

353 related articles for article (PubMed ID: 33741931)

  • 1. Stabilisation of half MCM ring by Cdt1 during DNA insertion.
    Guerrero-Puigdevall M; Fernandez-Fuentes N; Frigola J
    Nat Commun; 2021 Mar; 12(1):1746. PubMed ID: 33741931
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
    Yuan Z; Riera A; Bai L; Sun J; Nandi S; Spanos C; Chen ZA; Barbon M; Rappsilber J; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2017 Mar; 24(3):316-324. PubMed ID: 28191893
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cdt1 stabilizes an open MCM ring for helicase loading.
    Frigola J; He J; Kinkelin K; Pye VE; Renault L; Douglas ME; Remus D; Cherepanov P; Costa A; Diffley JFX
    Nat Commun; 2017 Jun; 8():15720. PubMed ID: 28643783
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
    Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
    Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer.
    Zhai Y; Cheng E; Wu H; Li N; Yung PY; Gao N; Tye BK
    Nat Struct Mol Biol; 2017 Mar; 24(3):300-308. PubMed ID: 28191894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases.
    Takara TJ; Bell SP
    EMBO J; 2011 Nov; 30(24):4885-96. PubMed ID: 22045335
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.
    Evrin C; Fernández-Cid A; Riera A; Zech J; Clarke P; Herrera MC; Tognetti S; Lurz R; Speck C
    Nucleic Acids Res; 2014 Feb; 42(4):2257-69. PubMed ID: 24234446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.
    Coster G; Frigola J; Beuron F; Morris EP; Diffley JF
    Mol Cell; 2014 Sep; 55(5):666-77. PubMed ID: 25087873
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA replication origins retain mobile licensing proteins.
    Sánchez H; McCluskey K; van Laar T; van Veen E; Asscher FM; Solano B; Diffley JFX; Dekker NH
    Nat Commun; 2021 Mar; 12(1):1908. PubMed ID: 33772005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
    Remus D; Beuron F; Tolun G; Griffith JD; Morris EP; Diffley JF
    Cell; 2009 Nov; 139(4):719-30. PubMed ID: 19896182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
    Fernández-Cid A; Riera A; Tognetti S; Herrera MC; Samel S; Evrin C; Winkler C; Gardenal E; Uhle S; Speck C
    Mol Cell; 2013 May; 50(4):577-88. PubMed ID: 23603117
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing.
    Zhai Y; Li N; Jiang H; Huang X; Gao N; Tye BK
    Mol Cell; 2017 Jul; 67(2):168-179. PubMed ID: 28732205
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.
    Sun J; Evrin C; Samel SA; Fernández-Cid A; Riera A; Kawakami H; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2013 Aug; 20(8):944-51. PubMed ID: 23851460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
    Feng X; Noguchi Y; Barbon M; Stillman B; Speck C; Li H
    Nat Commun; 2021 Jun; 12(1):3883. PubMed ID: 34162887
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.
    Ticau S; Friedman LJ; Ivica NA; Gelles J; Bell SP
    Cell; 2015 Apr; 161(3):513-525. PubMed ID: 25892223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A helicase-tethered ORC flip enables bidirectional helicase loading.
    Gupta S; Friedman LJ; Gelles J; Bell SP
    Elife; 2021 Dec; 10():. PubMed ID: 34882090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence.
    Warner MD; Azmi IF; Kang S; Zhao Y; Bell SP
    J Biol Chem; 2017 Dec; 292(52):21417-21430. PubMed ID: 29074622
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level.
    Duzdevich D; Warner MD; Ticau S; Ivica NA; Bell SP; Greene EC
    Mol Cell; 2015 May; 58(3):483-94. PubMed ID: 25921072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
    Evrin C; Fernández-Cid A; Zech J; Herrera MC; Riera A; Clarke P; Brill S; Lurz R; Speck C
    Nucleic Acids Res; 2013 Mar; 41(5):3162-72. PubMed ID: 23376927
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
    Schmidt JM; Bleichert F
    Nat Commun; 2020 Aug; 11(1):4263. PubMed ID: 32848132
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.