BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 33744296)

  • 1. Imiquimod Accelerated Antitumor Response by Targeting Lysosome Adaptation in Skin Cancer Cells.
    Chang SH; Wu CY; Chuang KC; Huang SW; Li ZY; Wang ST; Lai ZL; Chang CC; Chen YJ; Wong TW; Kao JK; Shieh JJ
    J Invest Dermatol; 2021 Sep; 141(9):2219-2228.e8. PubMed ID: 33744296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Imiquimod-induced ROS production causes lysosomal membrane permeabilization and activates caspase-8-mediated apoptosis in skin cancer cells.
    Chang SH; Lin PY; Wu TK; Hsu CS; Huang SW; Li ZY; Liu KT; Kao JK; Chen YJ; Wong TW; Wu CY; Shieh JJ
    J Dermatol Sci; 2022 Sep; 107(3):142-150. PubMed ID: 36075780
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Imiquimod-induced ROS production disrupts the balance of mitochondrial dynamics and increases mitophagy in skin cancer cells.
    Chuang KC; Chang CR; Chang SH; Huang SW; Chuang SM; Li ZY; Wang ST; Kao JK; Chen YJ; Shieh JJ
    J Dermatol Sci; 2020 Jun; 98(3):152-162. PubMed ID: 32376151
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity.
    Zhitomirsky B; Yunaev A; Kreiserman R; Kaplan A; Stark M; Assaraf YG
    Cell Death Dis; 2018 Dec; 9(12):1191. PubMed ID: 30546014
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells.
    Huang SW; Kao JK; Wu CY; Wang ST; Lee HC; Liang SM; Chen YJ; Shieh JJ
    Oncotarget; 2014 Mar; 5(5):1363-81. PubMed ID: 24658058
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice.
    Huang SW; Chen YJ; Wang ST; Ho LW; Kao JK; Narita M; Takahashi M; Wu CY; Cheng HY; Shieh JJ
    J Dermatol Sci; 2016 Oct; 84(1):59-70. PubMed ID: 27449383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Docetaxel enhances lysosomal function through TFEB activation.
    Zhang J; Wang J; Wong YK; Sun X; Chen Y; Wang L; Yang L; Lu L; Shen HM; Huang D
    Cell Death Dis; 2018 May; 9(6):614. PubMed ID: 29795139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcriptome profiling analysis reveals that ATP6V0E2 is involved in the lysosomal activation by anlotinib.
    Sun X; Shu Y; Yan P; Huang H; Gao R; Xu M; Lu L; Tian J; Huang D; Zhang J
    Cell Death Dis; 2020 Aug; 11(8):702. PubMed ID: 32839434
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance.
    Zhitomirsky B; Assaraf YG
    Oncotarget; 2015 Jan; 6(2):1143-56. PubMed ID: 25544758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endocytic regulation of cellular ion homeostasis controls lysosome biogenesis.
    López-Hernández T; Puchkov D; Krause E; Maritzen T; Haucke V
    Nat Cell Biol; 2020 Jul; 22(7):815-827. PubMed ID: 32601373
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
    Rusmini P; Cortese K; Crippa V; Cristofani R; Cicardi ME; Ferrari V; Vezzoli G; Tedesco B; Meroni M; Messi E; Piccolella M; Galbiati M; Garrè M; Morelli E; Vaccari T; Poletti A
    Autophagy; 2019 Apr; 15(4):631-651. PubMed ID: 30335591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice.
    Tanaka Y; Matsuwaki T; Yamanouchi K; Nishihara M
    Neuroscience; 2013 Oct; 250():8-19. PubMed ID: 23830905
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress.
    Li D; Shao R; Wang N; Zhou N; Du K; Shi J; Wang Y; Zhao Z; Ye X; Zhang X; Xu H
    Autophagy; 2021 Apr; 17(4):872-887. PubMed ID: 32138578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pseudoginsenoside F11 ameliorates the dysfunction of the autophagy-lysosomal pathway by activating calcineurin-mediated TFEB nuclear translocation in neuron during permanent cerebral ischemia.
    Fu X; Liu Y; Zhang H; Yu X; Wang X; Wu C; Yang J
    Exp Neurol; 2021 Apr; 338():113598. PubMed ID: 33422553
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis.
    Wang S; Ni HM; Chao X; Wang H; Bridges B; Kumer S; Schmitt T; Mareninova O; Gukovskaya A; De Lisle RC; Ballabio A; Pacher P; Ding WX
    Autophagy; 2019 Nov; 15(11):1954-1969. PubMed ID: 30894069
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB.
    Settembre C; Zoncu R; Medina DL; Vetrini F; Erdin S; Erdin S; Huynh T; Ferron M; Karsenty G; Vellard MC; Facchinetti V; Sabatini DM; Ballabio A
    EMBO J; 2012 Mar; 31(5):1095-108. PubMed ID: 22343943
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Imiquimod inhibits melanoma development by promoting pDC cytotoxic functions and impeding tumor vascularization.
    Aspord C; Tramcourt L; Leloup C; Molens JP; Leccia MT; Charles J; Plumas J
    J Invest Dermatol; 2014 Oct; 134(10):2551-2561. PubMed ID: 24751730
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line.
    Huang SW; Chang SH; Mu SW; Jiang HY; Wang ST; Kao JK; Huang JL; Wu CY; Chen YJ; Shieh JJ
    J Dermatol Sci; 2016 Mar; 81(3):182-91. PubMed ID: 26775629
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhancing lysosomal biogenesis and autophagic flux by activating the transcription factor EB protects against cadmium-induced neurotoxicity.
    Pi H; Li M; Tian L; Yang Z; Yu Z; Zhou Z
    Sci Rep; 2017 Feb; 7():43466. PubMed ID: 28240313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle.
    Arhzaouy K; Papadopoulos C; Schulze N; Pittman SK; Meyer H; Weihl CC
    Autophagy; 2019 Jun; 15(6):1082-1099. PubMed ID: 30654731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.