154 related articles for article (PubMed ID: 33755471)
1. Enhancing the Pharmacokinetics and Antitumor Activity of an α-Amanitin-Based Small-Molecule Drug Conjugate via Conjugation with an Fc Domain.
Gallo F; Korsak B; Müller C; Hechler T; Yanakieva D; Avrutina O; Kolmar H; Pahl A
J Med Chem; 2021 Apr; 64(7):4117-4129. PubMed ID: 33755471
[TBL] [Abstract][Full Text] [Related]
2. Bilirubin Nanoparticle-Assisted Delivery of a Small Molecule-Drug Conjugate for Targeted Cancer Therapy.
Lee S; Lee Y; Kim H; Lee DY; Jon S
Biomacromolecules; 2018 Jun; 19(6):2270-2277. PubMed ID: 29712433
[TBL] [Abstract][Full Text] [Related]
3. Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma.
Moldenhauer G; Salnikov AV; Lüttgau S; Herr I; Anderl J; Faulstich H
J Natl Cancer Inst; 2012 Apr; 104(8):622-34. PubMed ID: 22457476
[TBL] [Abstract][Full Text] [Related]
4. Modulation of drug-linker design to enhance in vivo potency of homogeneous antibody-drug conjugates.
Pabst M; McDowell W; Manin A; Kyle A; Camper N; De Juan E; Parekh V; Rudge F; Makwana H; Kantner T; Parekh H; Michelet A; Sheng X; Popa G; Tucker C; Khayrzad F; Pollard D; Kozakowska K; Resende R; Jenkins A; Simoes F; Morris D; Williams P; Badescu G; Baker MP; Bird M; Frigerio M; Godwin A
J Control Release; 2017 May; 253():160-164. PubMed ID: 28257988
[TBL] [Abstract][Full Text] [Related]
5. Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody-Drug Conjugates.
Matsuda Y; Seki T; Yamada K; Ooba Y; Takahashi K; Fujii T; Kawaguchi S; Narita T; Nakayama A; Kitahara Y; Mendelsohn BA; Okuzumi T
Mol Pharm; 2021 Nov; 18(11):4058-4066. PubMed ID: 34579528
[TBL] [Abstract][Full Text] [Related]
6. TP53 loss creates therapeutic vulnerability in colorectal cancer.
Liu Y; Zhang X; Han C; Wan G; Huang X; Ivan C; Jiang D; Rodriguez-Aguayo C; Lopez-Berestein G; Rao PH; Maru DM; Pahl A; He X; Sood AK; Ellis LM; Anderl J; Lu X
Nature; 2015 Apr; 520(7549):697-701. PubMed ID: 25901683
[TBL] [Abstract][Full Text] [Related]
7. Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand.
Amin TU; Emara R; Pal A; Aldawod H; Jiang G; Liang D; Haque Tuhin MT; Balgoname A; Patel AD; Alhamadsheh MM
J Med Chem; 2022 Nov; 65(22):15473-15486. PubMed ID: 36327103
[TBL] [Abstract][Full Text] [Related]
8. Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index.
McDonagh CF; Kim KM; Turcott E; Brown LL; Westendorf L; Feist T; Sussman D; Stone I; Anderson M; Miyamoto J; Lyon R; Alley SC; Gerber HP; Carter PJ
Mol Cancer Ther; 2008 Sep; 7(9):2913-23. PubMed ID: 18790772
[TBL] [Abstract][Full Text] [Related]
9. A Comparative Analysis of Fibroblast Activation Protein-Targeted Small Molecule-Drug, Antibody-Drug, and Peptide-Drug Conjugates.
Zana A; Puig-Moreno C; Bocci M; Gilardoni E; Di Nitto C; Principi L; Ravazza D; Rotta G; Prodi E; De Luca R; Neri D; Cazzamalli S
Bioconjug Chem; 2023 Jul; 34(7):1205-1211. PubMed ID: 37399501
[TBL] [Abstract][Full Text] [Related]
10. Tumoricidal effect of calicheamicin immuno-conjugates using a passive targeting strategy.
Boghaert ER; Khandke K; Sridharan L; Armellino D; Dougher M; Dijoseph JF; Kunz A; Hamann PR; Sridharan A; Jones S; Discafani C; Damle NK
Int J Oncol; 2006 Mar; 28(3):675-84. PubMed ID: 16465373
[TBL] [Abstract][Full Text] [Related]
11. Small molecule-drug conjugates: A novel strategy for cancer-targeted treatment.
Zhuang C; Guan X; Ma H; Cong H; Zhang W; Miao Z
Eur J Med Chem; 2019 Feb; 163():883-895. PubMed ID: 30580240
[TBL] [Abstract][Full Text] [Related]
12. Tumor Site-Specific Cleavage Improves the Antitumor Efficacy of Antibody-Drug Conjugates.
Xu K; Han J; Yang L; Cao L; Li S; Hong Z
Int J Mol Sci; 2023 Jul; 24(13):. PubMed ID: 37446189
[TBL] [Abstract][Full Text] [Related]
13. Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy.
Ning D; Xue J; Lou X; Shao R; Liu Y; Chen G
Arch Toxicol; 2024 Jun; 98(6):1705-1716. PubMed ID: 38555326
[TBL] [Abstract][Full Text] [Related]
14. Increased Tumor Penetration of Single-Domain Antibody-Drug Conjugates Improves
Nessler I; Khera E; Vance S; Kopp A; Qiu Q; Keating TA; Abu-Yousif AO; Sandal T; Legg J; Thompson L; Goodwin N; Thurber GM
Cancer Res; 2020 Mar; 80(6):1268-1278. PubMed ID: 31941698
[TBL] [Abstract][Full Text] [Related]
15. Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response.
Dela Cruz Chuh J; Go M; Chen Y; Guo J; Rafidi H; Mandikian D; Sun Y; Lin Z; Schneider K; Zhang P; Vij R; Sharpnack D; Chan P; de la Cruz C; Sadowsky J; Seshasayee D; Koerber JT; Pillow TH; Phillips GD; Rowntree RK; Boswell CA; Kozak KR; Polson AG; Polakis P; Yu SF; Dragovich PS; Agard NJ
MAbs; 2021; 13(1):1862452. PubMed ID: 33382956
[TBL] [Abstract][Full Text] [Related]
16. Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.
Dragovich PS; Pillow TH; Blake RA; Sadowsky JD; Adaligil E; Adhikari P; Chen J; Corr N; Dela Cruz-Chuh J; Del Rosario G; Fullerton A; Hartman SJ; Jiang F; Kaufman S; Kleinheinz T; Kozak KR; Liu L; Lu Y; Mulvihill MM; Murray JM; O'Donohue A; Rowntree RK; Sawyer WS; Staben LR; Wai J; Wang J; Wei B; Wei W; Xu Z; Yao H; Yu SF; Zhang D; Zhang H; Zhang S; Zhao Y; Zhou H; Zhu X
J Med Chem; 2021 Mar; 64(5):2576-2607. PubMed ID: 33596073
[TBL] [Abstract][Full Text] [Related]
17. Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics.
Kumar A; Mastren T; Wang B; Hsieh JT; Hao G; Sun X
Bioconjug Chem; 2016 Jul; 27(7):1681-9. PubMed ID: 27248781
[TBL] [Abstract][Full Text] [Related]
18. Antitumor activity of a 5T4 targeting antibody drug conjugate with a novel payload derived from MMAF via C-Lock linker.
Shi B; Wu M; Li Z; Xie Z; Wei X; Fan J; Xu Y; Ding D; Akash SH; Chen S; Cao S
Cancer Med; 2019 Apr; 8(4):1793-1805. PubMed ID: 30843650
[TBL] [Abstract][Full Text] [Related]
19. Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-FcγR Interaction.
Li F; Ulrich ML; Shih VF; Cochran JH; Hunter JH; Westendorf L; Neale J; Benjamin DR
Mol Cancer Ther; 2019 Apr; 18(4):780-787. PubMed ID: 30824607
[TBL] [Abstract][Full Text] [Related]
20. Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis.
Currier NV; Ackerman SE; Kintzing JR; Chen R; Filsinger Interrante M; Steiner A; Sato AK; Cochran JR
Mol Cancer Ther; 2016 Jun; 15(6):1291-300. PubMed ID: 27197305
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
