BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

585 related articles for article (PubMed ID: 33760024)

  • 21. Decoding transcriptomic signatures of cysteine string protein alpha-mediated synapse maintenance.
    Wang N; Zhu B; Allnutt MA; Grijalva RM; Zhao H; Chandra SS
    Proc Natl Acad Sci U S A; 2024 Jun; 121(24):e2320064121. PubMed ID: 38833477
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease.
    Frahm S; Melis V; Horsley D; Rickard JE; Riedel G; Fadda P; Scherma M; Harrington CR; Wischik CM; Theuring F; Schwab K
    Behav Brain Res; 2018 Feb; 339():153-168. PubMed ID: 29180135
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of bilateral changes in TID1 expression in the 6-OHDA rat model of Parkinson's disease.
    Proft J; Faraji J; Robbins JC; Zucchi FC; Zhao X; Metz GA; Braun JE
    PLoS One; 2011; 6(10):e26045. PubMed ID: 22016808
    [TBL] [Abstract][Full Text] [Related]  

  • 24. α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease.
    Levine PM; Galesic A; Balana AT; Mahul-Mellier AL; Navarro MX; De Leon CA; Lashuel HA; Pratt MR
    Proc Natl Acad Sci U S A; 2019 Jan; 116(5):1511-1519. PubMed ID: 30651314
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Neuroinflammation and α-synuclein accumulation in response to glucocerebrosidase deficiency are accompanied by synaptic dysfunction.
    Ginns EI; Mak SK; Ko N; Karlgren J; Akbarian S; Chou VP; Guo Y; Lim A; Samuelsson S; LaMarca ML; Vazquez-DeRose J; Manning-Boğ AB
    Mol Genet Metab; 2014 Feb; 111(2):152-62. PubMed ID: 24388731
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer's disease.
    Tiwari SS; d'Orange M; Troakes C; Shurovi BN; Engmann O; Noble W; Hortobágyi T; Giese KP
    Mol Brain; 2015 Jan; 8():6. PubMed ID: 25631211
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Is Cell Death Primary or Secondary in the Pathophysiology of Idiopathic Parkinson's Disease?
    Schulz-Schaeffer WJ
    Biomolecules; 2015 Jul; 5(3):1467-79. PubMed ID: 26193328
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.
    Naseri NN; Ergel B; Kharel P; Na Y; Huang Q; Huang R; Dolzhanskaya N; Burré J; Velinov MT; Sharma M
    Nat Struct Mol Biol; 2020 Feb; 27(2):192-201. PubMed ID: 32042150
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The Contribution of
    Longhena F; Faustini G; Missale C; Pizzi M; Spano P; Bellucci A
    Neural Plast; 2017; 2017():5012129. PubMed ID: 28133550
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmission.
    Xu F; Proft J; Gibbs S; Winkfein B; Johnson JN; Syed N; Braun JE
    PLoS One; 2010 Jun; 5(6):e11045. PubMed ID: 20548785
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice.
    Froula JM; Castellana-Cruz M; Anabtawi NM; Camino JD; Chen SW; Thrasher DR; Freire J; Yazdi AA; Fleming S; Dobson CM; Kumita JR; Cremades N; Volpicelli-Daley LA
    J Biol Chem; 2019 Jul; 294(27):10392-10406. PubMed ID: 31142553
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.
    Rockenstein E; Nuber S; Overk CR; Ubhi K; Mante M; Patrick C; Adame A; Trejo-Morales M; Gerez J; Picotti P; Jensen PH; Campioni S; Riek R; Winkler J; Gage FH; Winner B; Masliah E
    Brain; 2014 May; 137(Pt 5):1496-513. PubMed ID: 24662516
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]αSyn transgenic mice.
    Diepenbroek M; Casadei N; Esmer H; Saido TC; Takano J; Kahle PJ; Nixon RA; Rao MV; Melki R; Pieri L; Helling S; Marcus K; Krueger R; Masliah E; Riess O; Nuber S
    Hum Mol Genet; 2014 Aug; 23(15):3975-89. PubMed ID: 24619358
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The CSPalpha/G protein complex in PC12 cells.
    Bai L; Swayne LA; Braun JE
    Biochem Biophys Res Commun; 2007 Jan; 352(1):123-9. PubMed ID: 17113038
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein.
    Lam HA; Wu N; Cely I; Kelly RL; Hean S; Richter F; Magen I; Cepeda C; Ackerson LC; Walwyn W; Masliah E; Chesselet MF; Levine MS; Maidment NT
    J Neurosci Res; 2011 Jul; 89(7):1091-102. PubMed ID: 21488084
    [TBL] [Abstract][Full Text] [Related]  

  • 36. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
    Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
    Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dopamine-dependent early synaptic and motor dysfunctions induced by α-synuclein in the nigrostriatal circuit.
    Tozzi A; Sciaccaluga M; Loffredo V; Megaro A; Ledonne A; Cardinale A; Federici M; Bellingacci L; Paciotti S; Ferrari E; La Rocca A; Martini A; Mercuri NB; Gardoni F; Picconi B; Ghiglieri V; De Leonibus E; Calabresi P
    Brain; 2021 Dec; 144(11):3477-3491. PubMed ID: 34297092
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Initiation and propagation of α-synuclein aggregation in the nervous system.
    Hijaz BA; Volpicelli-Daley LA
    Mol Neurodegener; 2020 Mar; 15(1):19. PubMed ID: 32143659
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
    Pavia-Collado R; Cóppola-Segovia V; Miquel-Rio L; Alarcón-Aris D; Rodríguez-Aller R; Torres-López M; Paz V; Ruiz-Bronchal E; Campa L; Artigas F; Montefeltro A; Revilla R; Bortolozzi A
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805843
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Zonisamide attenuates α-synuclein neurotoxicity by an aggregation-independent mechanism in a rat model of familial Parkinson's disease.
    Arawaka S; Fukushima S; Sato H; Sasaki A; Koga K; Koyama S; Kato T
    PLoS One; 2014; 9(2):e89076. PubMed ID: 24586512
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 30.