BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 33760386)

  • 1. Genetic and Epigenetic Interplay Within a COLGALT2 Enhancer Associated With Osteoarthritis.
    Kehayova YS; Watson E; Wilkinson JM; Loughlin J; Rice SJ
    Arthritis Rheumatol; 2021 Oct; 73(10):1856-1865. PubMed ID: 33760386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mediation of the Same Epigenetic and Transcriptional Effect by Independent Osteoarthritis Risk-Conferring Alleles on a Shared Target Gene, COLGALT2.
    Kehayova YS; Wilkinson JM; Rice SJ; Loughlin J
    Arthritis Rheumatol; 2023 Jun; 75(6):910-922. PubMed ID: 36538011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Osteoarthritis genetic risk acting on the galactosyltransferase gene COLGALT2 has opposing functional effects in articulating joint tissues.
    Kehayova YS; Wilkinson JM; Rice SJ; Loughlin J
    Arthritis Res Ther; 2023 May; 25(1):83. PubMed ID: 37208701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multi-Tissue Epigenetic and Gene Expression Analysis Combined With Epigenome Modulation Identifies RWDD2B as a Target of Osteoarthritis Susceptibility.
    Parker E; Hofer IMJ; Rice SJ; Earl L; Anjum SA; Deehan DJ; Loughlin J
    Arthritis Rheumatol; 2021 Jan; 73(1):100-109. PubMed ID: 32755071
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of TMEM129, encoding a ubiquitin-protein ligase, as an effector gene of osteoarthritis genetic risk.
    Brumwell A; Aubourg G; Hussain J; Parker E; Deehan DJ; Rice SJ; Loughlin J
    Arthritis Res Ther; 2022 Aug; 24(1):189. PubMed ID: 35941660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic and Epigenetic Fine-Tuning of TGFB1 Expression Within the Human Osteoarthritic Joint.
    Rice SJ; Roberts JB; Tselepi M; Brumwell A; Falk J; Steven C; Loughlin J
    Arthritis Rheumatol; 2021 Oct; 73(10):1866-1877. PubMed ID: 33760378
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correlation of the osteoarthritis susceptibility variants that map to chromosome 20q13 with an expression quantitative trait locus operating on NCOA3 and with functional variation at the polymorphism rs116855380.
    Gee F; Rushton MD; Loughlin J; Reynard LN
    Arthritis Rheumatol; 2015 Nov; 67(11):2923-32. PubMed ID: 26211391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383.
    Reynard LN; Bui C; Syddall CM; Loughlin J
    Hum Genet; 2014 Aug; 133(8):1059-73. PubMed ID: 24861163
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multi-tissue epigenetic analysis of the osteoarthritis susceptibility locus mapping to the plectin gene PLEC.
    Sorial AK; Hofer IMJ; Tselepi M; Cheung K; Parker E; Deehan DJ; Rice SJ; Loughlin J
    Osteoarthritis Cartilage; 2020 Nov; 28(11):1448-1458. PubMed ID: 32580029
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic regulation of interleukin-8, an inflammatory chemokine, in osteoarthritis.
    Takahashi A; de Andrés MC; Hashimoto K; Itoi E; Oreffo RO
    Osteoarthritis Cartilage; 2015 Nov; 23(11):1946-54. PubMed ID: 26521741
    [TBL] [Abstract][Full Text] [Related]  

  • 11. STAT3 promotes a youthful epigenetic state in articular chondrocytes.
    Sarkar A; Liu NQ; Magallanes J; Tassey J; Lee S; Shkhyan R; Lee Y; Lu J; Ouyang Y; Tang H; Bian F; Tao L; Segil N; Ernst J; Lyons K; Horvath S; Evseenko D
    Aging Cell; 2023 Feb; 22(2):e13773. PubMed ID: 36638270
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence.
    Roberts JB; Boldvig OLG; Aubourg G; Kanchenapally ST; Deehan DJ; Rice SJ; Loughlin J
    Arthritis Res Ther; 2024 Apr; 26(1):78. PubMed ID: 38570801
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis.
    de Andrés MC; Imagawa K; Hashimoto K; Gonzalez A; Goldring MB; Roach HI; Oreffo RO
    Biochem Biophys Res Commun; 2011 Apr; 407(1):54-9. PubMed ID: 21352802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetic regulation of 15-lipoxygenase-1 expression in human chondrocytes by promoter methylation.
    Alsabri SG; Guedi GG; Najar M; Merimi M; Lavoie F; Grabs D; Fernandes J; Pelletier JP; Martel-Pelletier J; Benderdour M; Fahmi H
    Inflamm Res; 2023 Dec; 72(12):2145-2153. PubMed ID: 37874359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The epigenetic effect of glucosamine and a nuclear factor-kappa B (NF-kB) inhibitor on primary human chondrocytes--implications for osteoarthritis.
    Imagawa K; de Andrés MC; Hashimoto K; Pitt D; Itoi E; Goldring MB; Roach HI; Oreffo RO
    Biochem Biophys Res Commun; 2011 Feb; 405(3):362-7. PubMed ID: 21219853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis.
    Zhao L; Wang Q; Zhang C; Huang C
    Clin Rheumatol; 2017 Oct; 36(10):2335-2342. PubMed ID: 28470428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation.
    Imagawa K; de Andrés MC; Hashimoto K; Itoi E; Otero M; Roach HI; Goldring MB; Oreffo RO
    Arthritis Rheumatol; 2014 Nov; 66(11):3040-51. PubMed ID: 25048791
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide synthase is responsible for gene induction in human articular chondrocytes.
    de Andrés MC; Imagawa K; Hashimoto K; Gonzalez A; Roach HI; Goldring MB; Oreffo RO
    Arthritis Rheum; 2013 Mar; 65(3):732-42. PubMed ID: 23239081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci.
    Rice SJ; Tselepi M; Sorial AK; Aubourg G; Shepherd C; Almarza D; Skelton AJ; Pangou I; Deehan D; Reynard LN; Loughlin J
    Arthritis Rheumatol; 2019 Aug; 71(8):1285-1296. PubMed ID: 30730609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and analysis of methylation quantitative trait loci (mQTLs) mapping to novel osteoarthritis genetic risk signals.
    Rice SJ; Cheung K; Reynard LN; Loughlin J
    Osteoarthritis Cartilage; 2019 Oct; 27(10):1545-1556. PubMed ID: 31173883
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.