BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 33764774)

  • 1. Targeting Lysosomal Degradation Pathways: New Strategies and Techniques for Drug Discovery.
    Pei J; Wang G; Feng L; Zhang J; Jiang T; Sun Q; Ouyang L
    J Med Chem; 2021 Apr; 64(7):3493-3507. PubMed ID: 33764774
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LYST affects lysosome size and quantity, but not trafficking or degradation through autophagy or endocytosis.
    Holland P; Torgersen ML; Sandvig K; Simonsen A
    Traffic; 2014 Dec; 15(12):1390-405. PubMed ID: 25216107
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs.
    An S; Fu L
    EBioMedicine; 2018 Oct; 36():553-562. PubMed ID: 30224312
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Emerging protein degradation strategies: expanding the scope to extracellular and membrane proteins.
    Lin J; Jin J; Shen Y; Zhang L; Gong G; Bian H; Chen H; Nagle DG; Wu Y; Zhang W; Luan X
    Theranostics; 2021; 11(17):8337-8349. PubMed ID: 34373745
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeted protein degradation in drug development: Recent advances and future challenges.
    Song J; Hu M; Zhou J; Xie S; Li T; Li Y
    Eur J Med Chem; 2023 Dec; 261():115839. PubMed ID: 37778240
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Novel Lysosome Targeting Chimera for Targeted Protein Degradation via Split-and-Mix Strategy.
    Wang J; Wang Y; Yang F; Luo Q; Hou Z; Xing Y; Lu F; Li Z; Yin F
    ACS Chem Biol; 2024 May; 19(5):1161-1168. PubMed ID: 38662199
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Emerging targeted protein degradation tools for innovative drug discovery: From classical PROTACs to the novel and beyond.
    Zhong Y; Chi F; Wu H; Liu Y; Xie Z; Huang W; Shi W; Qian H
    Eur J Med Chem; 2022 Mar; 231():114142. PubMed ID: 35092900
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysosome-targeting chimaeras for degradation of extracellular proteins.
    Banik SM; Pedram K; Wisnovsky S; Ahn G; Riley NM; Bertozzi CR
    Nature; 2020 Aug; 584(7820):291-297. PubMed ID: 32728216
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteolysis targeting chimeras (PROTACs) for epigenetics research.
    Vogelmann A; Robaa D; Sippl W; Jung M
    Curr Opin Chem Biol; 2020 Aug; 57():8-16. PubMed ID: 32146413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Measuring the Overall Rate of Protein Breakdown in Cells and the Contributions of the Ubiquitin-Proteasome and Autophagy-Lysosomal Pathways.
    Sha Z; Zhao J; Goldberg AL
    Methods Mol Biol; 2018; 1844():261-276. PubMed ID: 30242715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cadmium-induced cytotoxicity in mouse liver cells is associated with the disruption of autophagic flux via inhibiting the fusion of autophagosomes and lysosomes.
    Zou H; Wang T; Yuan J; Sun J; Yuan Y; Gu J; Liu X; Bian J; Liu Z
    Toxicol Lett; 2020 Mar; 321():32-43. PubMed ID: 31862506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and pharmaceutical applications of proteolysis-targeting chimeric molecules.
    Liang Y; Nandakumar KS; Cheng K
    Biochem Pharmacol; 2020 Dec; 182():114211. PubMed ID: 32866456
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted Protein Degradation via Lysosomes.
    Paudel RR; Lu D; Roy Chowdhury S; Monroy EY; Wang J
    Biochemistry; 2023 Feb; 62(3):564-579. PubMed ID: 36130224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras.
    Ahn G; Riley NM; Kamber RA; Wisnovsky S; Moncayo von Hase S; Bassik MC; Banik SM; Bertozzi CR
    Science; 2023 Oct; 382(6668):eadf6249. PubMed ID: 37856615
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosome and related protein degradation technologies.
    Zheng H; Li G; Min J; Xu X; Huang W
    Drug Discov Today; 2023 Nov; 28(11):103767. PubMed ID: 37708931
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recent advances in epigenetic proteolysis targeting chimeras (Epi-PROTACs).
    Tomaselli D; Mautone N; Mai A; Rotili D
    Eur J Med Chem; 2020 Dec; 207():112750. PubMed ID: 32871345
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multifaceted targeted protein degradation systems for different cellular compartments.
    Zorca CE; Fallahi A; Luo S; Eldeeb MA
    Bioessays; 2022 Jun; 44(6):e2200008. PubMed ID: 35417040
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PROTACs- a game-changing technology.
    Konstantinidou M; Li J; Zhang B; Wang Z; Shaabani S; Ter Brake F; Essa K; Dömling A
    Expert Opin Drug Discov; 2019 Dec; 14(12):1255-1268. PubMed ID: 31538491
    [No Abstract]   [Full Text] [Related]  

  • 19. PROTACs: New method to degrade transcription regulating proteins.
    Hu B; Zhou Y; Sun D; Yang Y; Liu Y; Li X; Li H; Chen L
    Eur J Med Chem; 2020 Dec; 207():112698. PubMed ID: 32858471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs.
    Alabi SB; Crews CM
    J Biol Chem; 2021; 296():100647. PubMed ID: 33839157
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.