230 related articles for article (PubMed ID: 33770730)
1. Oridonin ameliorates noise-induced hearing loss by blocking NLRP3 - NEK7 mediated inflammasome activation.
Li M; Zhang Y; Qiu S; Zhuang W; Jiang W; Wang C; Zhang S; Zhou Z; Sun T; Ke Z; Guo W; Qiao Y; Shi X
Int Immunopharmacol; 2021 Jun; 95():107576. PubMed ID: 33770730
[TBL] [Abstract][Full Text] [Related]
2. NEK7 mediated assembly and activation of NLRP3 inflammasome downstream of potassium efflux in ventilator-induced lung injury.
Liu H; Gu C; Liu M; Liu G; Wang Y
Biochem Pharmacol; 2020 Jul; 177():113998. PubMed ID: 32353421
[TBL] [Abstract][Full Text] [Related]
3. Recent advances in the NEK7-licensed NLRP3 inflammasome activation: Mechanisms, role in diseases and related inhibitors.
Zhao N; Li CC; Di B; Xu LL
J Autoimmun; 2020 Sep; 113():102515. PubMed ID: 32703754
[TBL] [Abstract][Full Text] [Related]
4. Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation through blocking interaction between NLRP3 and NEK7.
Kim SK; Choe JY; Park KY
Biochem Biophys Res Commun; 2019 Sep; 517(2):338-345. PubMed ID: 31358323
[TBL] [Abstract][Full Text] [Related]
5. Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
He H; Jiang H; Chen Y; Ye J; Wang A; Wang C; Liu Q; Liang G; Deng X; Jiang W; Zhou R
Nat Commun; 2018 Jun; 9(1):2550. PubMed ID: 29959312
[TBL] [Abstract][Full Text] [Related]
6. Hit-to-Lead Optimization of the Natural Product Oridonin as Novel NLRP3 Inflammasome Inhibitors with Potent Anti-Inflammation Activity.
He C; Liu J; Li J; Wu H; Jiao C; Ze X; Xu S; Zhu Z; Guo W; Xu J; Yao H
J Med Chem; 2024 Jun; 67(11):9406-9430. PubMed ID: 38751194
[TBL] [Abstract][Full Text] [Related]
7. The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice.
Gao RF; Li X; Xiang HY; Yang H; Lv CY; Sun XL; Chen HZ; Gao Y; Yang JS; Luo W; Yang YQ; Tang YH
Int Immunopharmacol; 2021 Jan; 90():107133. PubMed ID: 33168408
[TBL] [Abstract][Full Text] [Related]
8. The selective Nlrp3 inflammasome inhibitor Mcc950 attenuates lung ischemia-reperfusion injury.
Xu KY; Wu CY; Tong S; Xiong P; Wang SH
Biochem Biophys Res Commun; 2018 Sep; 503(4):3031-3037. PubMed ID: 30146255
[TBL] [Abstract][Full Text] [Related]
9. Oridonin employs interleukin 1 receptor type 2 to treat noise-induced hearing loss by blocking inner ear inflammation.
Chen MB; Li MH; Wu LY; Wang R; Long X; Zhang L; Sun W; Guo WW; Pan Y; Zhang YS; Lin C; Shi X; Yang SM
Biochem Pharmacol; 2023 Apr; 210():115457. PubMed ID: 36806583
[TBL] [Abstract][Full Text] [Related]
10. Oridonin ameliorates insulin resistance partially through inhibition of inflammatory response in rats subjected to chronic unpredictable mild stress.
Liang L; Zheng Y; Xie Y; Xiao L; Wang G
Int Immunopharmacol; 2021 Feb; 91():107298. PubMed ID: 33388733
[TBL] [Abstract][Full Text] [Related]
11. NEK7: a potential therapy target for NLRP3-related diseases.
Liu G; Chen X; Wang Q; Yuan L
Biosci Trends; 2020 May; 14(2):74-82. PubMed ID: 32295992
[TBL] [Abstract][Full Text] [Related]
12. NEK7-Mediated Activation of NLRP3 Inflammasome Is Coordinated by Potassium Efflux/Syk/JNK Signaling During
Liu R; Liu Y; Liu C; Gao A; Wang L; Tang H; Wu Q; Wang X; Tian D; Qi Z; Shen Y
Front Immunol; 2021; 12():747370. PubMed ID: 34603335
[No Abstract] [Full Text] [Related]
13. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.
He Y; Zeng MY; Yang D; Motro B; Núñez G
Nature; 2016 Feb; 530(7590):354-7. PubMed ID: 26814970
[TBL] [Abstract][Full Text] [Related]
14. Oridonin alleviates kanamycin-related hearing loss by inhibiting NLRP3/caspase-1/gasdermin D-induced inflammasome activation and hair cell pyroptosis.
Wu L; Chen M; Li M; Wang Y; Li Y; Zheng L; Ke Z; Liu K; Qiao Y; Shi X
Mol Immunol; 2022 Sep; 149():66-76. PubMed ID: 35749835
[TBL] [Abstract][Full Text] [Related]
15. PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.
Yang XD; Li W; Zhang S; Wu D; Jiang X; Tan R; Niu X; Wang Q; Wu X; Liu Z; Chen LF; Qin J; Su B
EMBO J; 2020 Jan; 39(2):e102201. PubMed ID: 31762063
[TBL] [Abstract][Full Text] [Related]
16. Helenine blocks NLRP3 activation by disrupting the NEK7-NLRP3 interaction and ameliorates inflammatory diseases.
Fang ZE; Wang Y; Bian S; Qin S; Zhao H; Wen J; Liu T; Ren L; Li Q; Shi W; Zhao J; Yang H; Peng R; Wang Q; Bai Z; Xu G
Phytomedicine; 2024 Jan; 122():155159. PubMed ID: 37931457
[TBL] [Abstract][Full Text] [Related]
17. Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
Shao A; Wu H; Hong Y; Tu S; Sun X; Wu Q; Zhao Q; Zhang J; Sheng J
Mol Neurobiol; 2016 Jul; 53(5):3462-3476. PubMed ID: 26091790
[TBL] [Abstract][Full Text] [Related]
18. Estradiol inhibits NLRP3 inflammasome in fibroblast-like synoviocytes activated by lipopolysaccharide and adenosine triphosphate.
Shi J; Zhao W; Ying H; Zhang Y; Du J; Chen S; Li J; Shen B
Int J Rheum Dis; 2018 Nov; 21(11):2002-2010. PubMed ID: 29105345
[TBL] [Abstract][Full Text] [Related]
19. Assessment of NLRP3 Inflammasome Activation and NLRP3-NEK7 Complex Assembly.
Kelley N; He Y
Methods Mol Biol; 2023; 2641():17-26. PubMed ID: 37074638
[TBL] [Abstract][Full Text] [Related]
20. Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation.
Hughes MM; Hooftman A; Angiari S; Tummala P; Zaslona Z; Runtsch MC; McGettrick AF; Sutton CE; Diskin C; Rooke M; Takahashi S; Sundararaj S; Casarotto MG; Dahlstrom JE; Palsson-McDermott EM; Corr SC; Mills KHG; Preston RJS; Neamati N; Xie Y; Baell JB; Board PG; O'Neill LAJ
Cell Rep; 2019 Oct; 29(1):151-161.e5. PubMed ID: 31577945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]