These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 33775637)

  • 1. The structural basis of Akt PH domain interaction with calmodulin.
    Weako J; Jang H; Keskin O; Nussinov R; Gursoy A
    Biophys J; 2021 May; 120(10):1994-2008. PubMed ID: 33775637
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt.
    Agamasu C; Ghanam RH; Xu F; Sun Y; Chen Y; Saad JS
    J Biol Chem; 2017 Jan; 292(1):251-263. PubMed ID: 27872186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt.
    Agamasu C; Ghanam RH; Saad JS
    J Biol Chem; 2015 Nov; 290(45):27403-27413. PubMed ID: 26391397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Calmodulin and IQGAP1 activation of PI3Kα and Akt in KRAS, HRAS and NRAS-driven cancers.
    Nussinov R; Zhang M; Tsai CJ; Jang H
    Biochim Biophys Acta Mol Basis Dis; 2018 Jun; 1864(6 Pt B):2304-2314. PubMed ID: 29097261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphorylated Calmodulin Promotes PI3K Activation by Binding to the SH
    Zhang M; Jang H; Gaponenko V; Nussinov R
    Biophys J; 2017 Nov; 113(9):1956-1967. PubMed ID: 29117520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Flexible-body motions of calmodulin and the farnesylated hypervariable region yield a high-affinity interaction enabling K-Ras4B membrane extraction.
    Jang H; Banerjee A; Chavan T; Gaponenko V; Nussinov R
    J Biol Chem; 2017 Jul; 292(30):12544-12559. PubMed ID: 28623230
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ca(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.
    Dong B; Valencia CA; Liu R
    J Biol Chem; 2007 Aug; 282(34):25131-40. PubMed ID: 17580302
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PH domain-mediated autoinhibition and oncogenic activation of Akt.
    Bae H; Viennet T; Park E; Chu N; Salguero A; Eck MJ; Arthanari H; Cole PA
    Elife; 2022 Aug; 11():. PubMed ID: 35968932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin.
    Jang H; Banerjee A; Marcus K; Makowski L; Mattos C; Gaponenko V; Nussinov R
    Structure; 2019 Nov; 27(11):1647-1659.e4. PubMed ID: 31495533
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation.
    Tibes R; Kornblau SM; Qiu Y; Mousses SM; Robbins C; Moses T; Carpten JD
    Br J Haematol; 2008 Feb; 140(3):344-7. PubMed ID: 18053070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.
    Li X; Dai J; Ni D; He X; Zhang H; Zhang J; Fu Q; Liu Y; Lu S
    Int J Biol Macromol; 2020 Feb; 144():643-655. PubMed ID: 31816384
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calmodulin and PI3K Signaling in
    Nussinov R; Wang G; Tsai CJ; Jang H; Lu S; Banerjee A; Zhang J; Gaponenko V
    Trends Cancer; 2017 Mar; 3(3):214-224. PubMed ID: 28462395
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α.
    Zhang M; Li Z; Wang G; Jang H; Sacks DB; Zhang J; Gaponenko V; Nussinov R
    J Phys Chem B; 2018 Dec; 122(49):11137-11146. PubMed ID: 30047727
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational Insights into the Interactions between Calmodulin and the c/nSH2 Domains of p85α Regulatory Subunit of PI3Kα: Implication for PI3Kα Activation by Calmodulin.
    Ni D; Liu D; Zhang J; Lu S
    Int J Mol Sci; 2018 Jan; 19(1):. PubMed ID: 29300353
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structural basis for Ras activation of PI3Kα lipid kinase.
    Zhang M; Jang H; Nussinov R
    Phys Chem Chem Phys; 2019 Jun; 21(22):12021-12028. PubMed ID: 31135801
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
    Rodríguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
    Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module.
    Ziemba BP; Swisher GH; Masson G; Burke JE; Williams RL; Falke JJ
    Biochemistry; 2016 Nov; 55(46):6395-6405. PubMed ID: 27933776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of AKT Activity by Inhibition of the Pleckstrin Homology Domain-PtdIns(3,4,5)P
    Kang Y; Jang G; Ahn S; Lee Y; Shim SY; Yoon Y
    J Microbiol Biotechnol; 2018 Aug; 28(8):1401-1411. PubMed ID: 30301316
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chlormequat chloride induced activation of calmodulin mediated PI3K/AKT signaling pathway led to impaired sperm quality in pubertal mice.
    Wang X; Kang C; Guo W; Yuan L; Zhang H; Zhang Q; Xiao Q; Hao W
    Food Chem Toxicol; 2024 Mar; 185():114475. PubMed ID: 38286265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras.
    Akagi T; Murata K; Shishido T; Hanafusa H
    Mol Cell Biol; 2002 Oct; 22(20):7015-23. PubMed ID: 12242282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.