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3. Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5,8-dideazafolic acid. Lorico A; Toffoli G; Boiocchi M; Erba E; Broggini M; Rappa G; D'Incalci M Cancer Res; 1988 Apr; 48(8):2036-41. PubMed ID: 3349474 [TBL] [Abstract][Full Text] [Related]
4. N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate. Takemura Y; Ohnuma T Mt Sinai J Med; 1992 Oct; 59(5):419-24. PubMed ID: 1435841 [TBL] [Abstract][Full Text] [Related]
5. Activity of the thymidylate synthase inhibitor 2-desamino-N10-propargyl-5,8-dideazafolic acid and related compounds in murine (L1210) and human (W1L2) systems in vitro and in L1210 in vivo. Jackman AL; Taylor GA; O'Connor BM; Bishop JA; Moran RG; Calvert AH Cancer Res; 1990 Sep; 50(17):5212-8. PubMed ID: 2386929 [TBL] [Abstract][Full Text] [Related]
6. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors. Jansen G; Schornagel JH; Westerhof GR; Rijksen G; Newell DR; Jackman AL Cancer Res; 1990 Dec; 50(23):7544-8. PubMed ID: 2253202 [TBL] [Abstract][Full Text] [Related]
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10. Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole. Curtin NJ; Harris AL; Aherne GW Cancer Res; 1991 May; 51(9):2346-52. PubMed ID: 2015598 [TBL] [Abstract][Full Text] [Related]
11. Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase. Cheng YC; Dutschman GE; Starnes MC; Fisher MH; Nanavathi NT; Nair MG Cancer Res; 1985 Feb; 45(2):598-600. PubMed ID: 3917852 [TBL] [Abstract][Full Text] [Related]
13. Substituted-2-desamino-2-methyl-quinazolinones. A series of novel antitumour agents. Boyle FT; Matusiak ZS; Hughes LR; Slater AM; Stephens TC; Smith MN; Brown M; Kimbell R; Jackman AL Adv Exp Med Biol; 1993; 338():585-8. PubMed ID: 8304185 [No Abstract] [Full Text] [Related]
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20. ICI D1694, a quinazoline antifolate thymidylate synthase inhibitor that is a potent inhibitor of L1210 tumor cell growth in vitro and in vivo: a new agent for clinical study. Jackman AL; Taylor GA; Gibson W; Kimbell R; Brown M; Calvert AH; Judson IR; Hughes LR Cancer Res; 1991 Oct; 51(20):5579-86. PubMed ID: 1913676 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]