348 related articles for article (PubMed ID: 33782411)
1. The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation.
Shang M; Yang H; Yang R; Chen T; Fu Y; Li Y; Fang X; Zhang K; Zhang J; Li H; Cao X; Gu J; Xiao J; Zhang Q; Liu X; Yu Q; Wang T
Nat Commun; 2021 Mar; 12(1):1940. PubMed ID: 33782411
[TBL] [Abstract][Full Text] [Related]
2. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.
Ju HQ; Lu YX; Chen DL; Zuo ZX; Liu ZX; Wu QN; Mo HY; Wang ZX; Wang DS; Pu HY; Zeng ZL; Li B; Xie D; Huang P; Hung MC; Chiao PJ; Xu RH
J Natl Cancer Inst; 2019 Jun; 111(6):584-596. PubMed ID: 30534944
[TBL] [Abstract][Full Text] [Related]
3. Down-regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle-related genes.
Yu C; Yang L; Cai M; Zhou F; Xiao S; Li Y; Wan T; Cheng D; Wang L; Zhao C; Huang X
J Cell Mol Med; 2020 Jan; 24(2):1568-1577. PubMed ID: 31778025
[TBL] [Abstract][Full Text] [Related]
4. MTHFD2 promotes tumorigenesis and metastasis in lung adenocarcinoma by regulating AKT/GSK-3β/β-catenin signalling.
Shi Y; Xu Y; Yao J; Yan C; Su H; Zhang X; Chen E; Ying K
J Cell Mol Med; 2021 Jul; 25(14):7013-7027. PubMed ID: 34121323
[TBL] [Abstract][Full Text] [Related]
5. Non-metabolic function of MTHFD2 activates CDK2 in bladder cancer.
Liu X; Liu S; Piao C; Zhang Z; Zhang X; Jiang Y; Kong C
Cancer Sci; 2021 Dec; 112(12):4909-4919. PubMed ID: 34632667
[TBL] [Abstract][Full Text] [Related]
6. MTHFD2 Overexpression Predicts Poor Prognosis in Renal Cell Carcinoma and is Associated with Cell Proliferation and Vimentin-Modulated Migration and Invasion.
Lin H; Huang B; Wang H; Liu X; Hong Y; Qiu S; Zheng J
Cell Physiol Biochem; 2018; 51(2):991-1000. PubMed ID: 30466107
[TBL] [Abstract][Full Text] [Related]
7. MicroRNA-33a-5p suppresses colorectal cancer cell growth by inhibiting MTHFD2.
Yan Y; Zhang D; Lei T; Zhao C; Han J; Cui J; Wang Y
Clin Exp Pharmacol Physiol; 2019 Oct; 46(10):928-936. PubMed ID: 31209892
[TBL] [Abstract][Full Text] [Related]
8. p53 deficiency induces MTHFD2 transcription to promote cell proliferation and restrain DNA damage.
Li G; Wu J; Li L; Jiang P
Proc Natl Acad Sci U S A; 2021 Jul; 118(28):. PubMed ID: 34244426
[TBL] [Abstract][Full Text] [Related]
9. ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis.
Gao Y; Feng L; Zhang L; Geng J; Zhang E
Dis Markers; 2022; 2022():7527996. PubMed ID: 36051358
[TBL] [Abstract][Full Text] [Related]
10. Up-regulation of MTHFD2 is associated with clinicopathological characteristics and poor survival in ovarian cancer, possibly by regulating MOB1A signaling.
Cui X; Su H; Yang J; Wu X; Huo K; Jing X; Zhang S
J Ovarian Res; 2022 Feb; 15(1):23. PubMed ID: 35135596
[TBL] [Abstract][Full Text] [Related]
11. A novel oral inhibitor for one-carbon metabolism and checkpoint kinase 1 inhibitor as a rational combination treatment for breast cancer.
Lee J; Chen X; Wang Y; Nishimura T; Li M; Ishikawa S; Daikoku T; Kawai J; Tojo A; Gotoh N
Biochem Biophys Res Commun; 2021 Dec; 584():7-14. PubMed ID: 34753066
[TBL] [Abstract][Full Text] [Related]
12. Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2.
Nishimura T; Nakata A; Chen X; Nishi K; Meguro-Horike M; Sasaki S; Kita K; Horike SI; Saitoh K; Kato K; Igarashi K; Murayama T; Kohno S; Takahashi C; Mukaida N; Yano S; Soga T; Tojo A; Gotoh N
Oncogene; 2019 Apr; 38(14):2464-2481. PubMed ID: 30532069
[TBL] [Abstract][Full Text] [Related]
13. miR-92a Inhibits Proliferation and Induces Apoptosis by Regulating Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) Expression in Acute Myeloid Leukemia.
Gu Y; Si J; Xiao X; Tian Y; Yang S
Oncol Res; 2017 Aug; 25(7):1069-1079. PubMed ID: 28059050
[TBL] [Abstract][Full Text] [Related]
14. High Expression of Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2) in Esophageal Squamous Cell Carcinoma and its Clinical Prognostic Significance.
He H; Li PC; Jia W; Hu B; Ji CS
Med Sci Monit; 2020 Feb; 26():e920259. PubMed ID: 32088725
[TBL] [Abstract][Full Text] [Related]
15. Folate enzyme MTHFD2 links one-carbon metabolism to unfolded protein response in glioblastoma.
Zhu Z; Kiang KM; Li N; Liu J; Zhang P; Jin L; He X; Zhang S; Leung GK
Cancer Lett; 2022 Nov; 549():215903. PubMed ID: 36089117
[TBL] [Abstract][Full Text] [Related]
16. Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Bonagas N; Gustafsson NMS; Henriksson M; Marttila P; Gustafsson R; Wiita E; Borhade S; Green AC; Vallin KSA; Sarno A; Svensson R; Göktürk C; Pham T; Jemth AS; Loseva O; Cookson V; Kiweler N; Sandberg L; Rasti A; Unterlass JE; Haraldsson M; Andersson Y; Scaletti ER; Bengtsson C; Paulin CBJ; Sanjiv K; Abdurakhmanov E; Pudelko L; Kunz B; Desroses M; Iliev P; Färnegårdh K; Krämer A; Garg N; Michel M; Häggblad S; Jarvius M; Kalderén C; Jensen AB; Almlöf I; Karsten S; Zhang SM; Häggblad M; Eriksson A; Liu J; Glinghammar B; Nekhotiaeva N; Klingegård F; Koolmeister T; Martens U; Llona-Minguez S; Moulson R; Nordström H; Parrow V; Dahllund L; Sjöberg B; Vargas IL; Vo DD; Wannberg J; Knapp S; Krokan HE; Arvidsson PI; Scobie M; Meiser J; Stenmark P; Berglund UW; Homan EJ; Helleday T
Nat Cancer; 2022 Feb; 3(2):156-172. PubMed ID: 35228749
[TBL] [Abstract][Full Text] [Related]
17. Xanthine Derivatives Reveal an Allosteric Binding Site in Methylenetetrahydrofolate Dehydrogenase 2 (MTHFD2).
Lee LC; Peng YH; Chang HH; Hsu T; Lu CT; Huang CH; Hsueh CC; Kung FC; Kuo CC; Jiaang WT; Wu SY
J Med Chem; 2021 Aug; 64(15):11288-11301. PubMed ID: 34337952
[TBL] [Abstract][Full Text] [Related]
18. Neddylation inhibition upregulates PD-L1 expression and enhances the efficacy of immune checkpoint blockade in glioblastoma.
Zhou S; Zhao X; Yang Z; Yang R; Chen C; Zhao K; Wang W; Ma Y; Zhang Q; Wang X
Int J Cancer; 2019 Aug; 145(3):763-774. PubMed ID: 31044422
[TBL] [Abstract][Full Text] [Related]
19. Cisplatin inhibits SIRT3-deacetylation MTHFD2 to disturb cellular redox balance in colorectal cancer cell.
Wan X; Wang C; Huang Z; Zhou D; Xiang S; Qi Q; Chen X; Arbely E; Liu CY; Du P; Yu W
Cell Death Dis; 2020 Aug; 11(8):649. PubMed ID: 32811824
[TBL] [Abstract][Full Text] [Related]
20. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer.
Nilsson R; Jain M; Madhusudhan N; Sheppard NG; Strittmatter L; Kampf C; Huang J; Asplund A; Mootha VK
Nat Commun; 2014; 5():3128. PubMed ID: 24451681
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
