BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 33790356)

  • 1. DOT1L inhibitors block abnormal self-renewal induced by cohesin loss.
    Heimbruch KE; Fisher JB; Stelloh CT; Phillips E; Reimer MH; Wargolet AJ; Meyer AE; Pulakanti K; Viny AD; Loppnow JJ; Levine RL; Pulikkan JA; Zhu N; Rao S
    Sci Rep; 2021 Mar; 11(1):7288. PubMed ID: 33790356
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9.
    Fisher JB; Peterson J; Reimer M; Stelloh C; Pulakanti K; Gerbec ZJ; Abel AM; Strouse JM; Strouse C; McNulty M; Malarkannan S; Crispino JD; Milanovich S; Rao S
    Leukemia; 2017 Mar; 31(3):712-719. PubMed ID: 27554164
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.
    Wang WT; Chen TQ; Zeng ZC; Pan Q; Huang W; Han C; Fang K; Sun LY; Yang QQ; Wang D; Luo XQ; Sun YM; Chen YQ
    J Hematol Oncol; 2020 Jun; 13(1):78. PubMed ID: 32552847
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epigenetic regulation of protein translation in KMT2A-rearranged AML.
    Lenard A; Xie HM; Pastuer T; Shank T; Libbrecht C; Kingsley M; Riedel SS; Yuan ZF; Zhu N; Neff T; Bernt KM
    Exp Hematol; 2020 May; 85():57-69. PubMed ID: 32437908
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cohesin Mutations in Myeloid Malignancies.
    Fisher JB; McNulty M; Burke MJ; Crispino JD; Rao S
    Trends Cancer; 2017 Apr; 3(4):282-293. PubMed ID: 28626802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
    Cuartero S; Weiss FD; Dharmalingam G; Guo Y; Ing-Simmons E; Masella S; Robles-Rebollo I; Xiao X; Wang YF; Barozzi I; Djeghloul D; Amano MT; Niskanen H; Petretto E; Dowell RD; Tachibana K; Kaikkonen MU; Nasmyth KA; Lenhard B; Natoli G; Fisher AG; Merkenschlager M
    Nat Immunol; 2018 Sep; 19(9):932-941. PubMed ID: 30127433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of mutations in the cohesin complex in acute myeloid leukemia.
    Mazumdar C; Majeti R
    Int J Hematol; 2017 Jan; 105(1):31-36. PubMed ID: 27796738
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
    Rau RE; Rodriguez BA; Luo M; Jeong M; Rosen A; Rogers JH; Campbell CT; Daigle SR; Deng L; Song Y; Sweet S; Chevassut T; Andreeff M; Kornblau SM; Li W; Goodell MA
    Blood; 2016 Aug; 128(7):971-81. PubMed ID: 27335278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
    Riedel SS; Haladyna JN; Bezzant M; Stevens B; Pollyea DA; Sinha AU; Armstrong SA; Wei Q; Pollock RM; Daigle SR; Jordan CT; Ernst P; Neff T; Bernt KM
    J Clin Invest; 2016 Apr; 126(4):1438-50. PubMed ID: 26927674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The methyltransferase G9a regulates HoxA9-dependent transcription in AML.
    Lehnertz B; Pabst C; Su L; Miller M; Liu F; Yi L; Zhang R; Krosl J; Yung E; Kirschner J; Rosten P; Underhill TM; Jin J; Hébert J; Sauvageau G; Humphries RK; Rossi FM
    Genes Dev; 2014 Feb; 28(4):317-27. PubMed ID: 24532712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A cohesive look at leukemogenesis: The cohesin complex and other driving mutations in AML.
    Heimbruch KE; Meyer AE; Agrawal P; Viny AD; Rao S
    Neoplasia; 2021 Mar; 23(3):337-347. PubMed ID: 33621854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.
    Liu W; Deng L; Song Y; Redell M
    PLoS One; 2014; 9(5):e98270. PubMed ID: 24858818
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer.
    Yang L; Lei Q; Li L; Yang J; Dong Z; Cui H
    Clin Epigenetics; 2019 Dec; 11(1):199. PubMed ID: 31888761
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia.
    Guo H; Chu Y; Wang L; Chen X; Chen Y; Cheng H; Zhang L; Zhou Y; Yang FC; Cheng T; Xu M; Zhang X; Zhou J; Yuan W
    Int J Cancer; 2017 Jul; 141(2):324-335. PubMed ID: 28411381
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes.
    Rivas MA; Durmaz C; Kloetgen A; Chin CR; Chen Z; Bhinder B; Koren A; Viny AD; Scharer CD; Boss JM; Elemento O; Mason CE; Melnick AM
    Front Immunol; 2021; 12():688493. PubMed ID: 34621263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis.
    Li A; Yang Y; Gao C; Lu J; Jeong HW; Liu BH; Tang P; Yao X; Neuberg D; Huang G; Tenen DG; Chai L
    J Clin Invest; 2013 Oct; 123(10):4195-207. PubMed ID: 24051379
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Leukemia-Associated Cohesin Mutants Dominantly Enforce Stem Cell Programs and Impair Human Hematopoietic Progenitor Differentiation.
    Mazumdar C; Shen Y; Xavy S; Zhao F; Reinisch A; Li R; Corces MR; Flynn RA; Buenrostro JD; Chan SM; Thomas D; Koenig JL; Hong WJ; Chang HY; Majeti R
    Cell Stem Cell; 2015 Dec; 17(6):675-688. PubMed ID: 26607380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia.
    Zhu G; Luo H; Feng Y; Guryanova OA; Xu J; Chen S; Lai Q; Sharma A; Xu B; Zhao Z; Feng R; Ni H; Claxton D; Guo Y; Mesa RA; Qiu Y; Yang FC; Li W; Nimer SD; Huang S; Xu M
    Nat Commun; 2021 Mar; 12(1):1956. PubMed ID: 33782403
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis.
    Viny AD; Ott CJ; Spitzer B; Rivas M; Meydan C; Papalexi E; Yelin D; Shank K; Reyes J; Chiu A; Romin Y; Boyko V; Thota S; Maciejewski JP; Melnick A; Bradner JE; Levine RL
    J Exp Med; 2015 Oct; 212(11):1819-32. PubMed ID: 26438361
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.