BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 33791883)

  • 1. Age-Related Changes in Pediatric Physiology: Quantitative Analysis of Organ Weights and Blood Flows : Age-Related Changes in Pediatric Physiology.
    Chang HP; Kim SJ; Wu D; Shah K; Shah DK
    AAPS J; 2021 Mar; 23(3):50. PubMed ID: 33791883
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development and evaluation of a generic physiologically based pharmacokinetic model for children.
    Edginton AN; Schmitt W; Willmann S
    Clin Pharmacokinet; 2006; 45(10):1013-34. PubMed ID: 16984214
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.
    Willmann S; Höhn K; Edginton A; Sevestre M; Solodenko J; Weiss W; Lippert J; Schmitt W
    J Pharmacokinet Pharmacodyn; 2007 Jun; 34(3):401-31. PubMed ID: 17431751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling: theophylline and midazolam as model drugs.
    Björkman S
    Br J Clin Pharmacol; 2005 Jun; 59(6):691-704. PubMed ID: 15948934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals.
    Schlender JF; Meyer M; Thelen K; Krauss M; Willmann S; Eissing T; Jaehde U
    Clin Pharmacokinet; 2016 Dec; 55(12):1573-1589. PubMed ID: 27351180
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Model qualification of the PK-Sim® pediatric module for pediatric exposure assessment of CYP450 metabolized compounds.
    Yun YE; Edginton AN
    J Toxicol Environ Health A; 2019; 82(14):789-814. PubMed ID: 31405354
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model.
    Rashid M; Sarfraz M; Arafat M; Hussain A; Abbas N; Sadiq MW; Rasool MF; Bukhari NI
    BMC Pharmacol Toxicol; 2020 Jul; 21(1):56. PubMed ID: 32727574
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows-A Physiologically Based Pharmacokinetic Approach.
    Rasool MF; Khalil F; Läer S
    Drug Metab Dispos; 2016 Jul; 44(7):1103-15. PubMed ID: 27068272
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Organ weights and blood flows of sheep and pig for physiological pharmacokinetic modelling.
    Upton RN
    J Pharmacol Toxicol Methods; 2008; 58(3):198-205. PubMed ID: 18775498
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PBPK and its Virtual Populations: the Impact of Physiology on Pediatric Pharmacokinetic Predictions of Tramadol.
    T'jollyn H; Vermeulen A; Van Bocxlaer J
    AAPS J; 2018 Nov; 21(1):8. PubMed ID: 30498862
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population.
    Maglalang PD; Sinha J; Zimmerman K; McCann S; Edginton A; Hornik CP; Hornik CD; Muller WJ; Al-Uzri A; Meyer M; Chen JY; Anand R; Perrin EM; Gonzalez D;
    Clin Pharmacokinet; 2024 Jun; 63(6):885-899. PubMed ID: 38814425
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A physiologically based pharmacokinetic drug-disease model to predict carvedilol exposure in adult and paediatric heart failure patients by incorporating pathophysiological changes in hepatic and renal blood flows.
    Rasool MF; Khalil F; Läer S
    Clin Pharmacokinet; 2015 Sep; 54(9):943-62. PubMed ID: 25773479
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of age-related changes in body weight and organ weights from birth to adolescence in humans.
    Haddad S; Restieri C; Krishnan K
    J Toxicol Environ Health A; 2001 Nov; 64(6):453-64. PubMed ID: 11732696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Changes in individual drug-independent system parameters during virtual paediatric pharmacokinetic trials: introducing time-varying physiology into a paediatric PBPK model.
    Abduljalil K; Jamei M; Rostami-Hodjegan A; Johnson TN
    AAPS J; 2014 May; 16(3):568-76. PubMed ID: 24700271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Repository Describing the Anatomical, Physiological, and Biological Changes in an Obese Population to Inform Physiologically Based Pharmacokinetic Models.
    Berton M; Bettonte S; Stader F; Battegay M; Marzolini C
    Clin Pharmacokinet; 2022 Sep; 61(9):1251-1270. PubMed ID: 35699913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A physiologically based pharmacokinetic computer model for human pregnancy.
    Luecke RH; Wosilait WD; Pearce BA; Young JF
    Teratology; 1994 Feb; 49(2):90-103. PubMed ID: 8016750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Generic physiologically based kinetic modelling for farm animals: Part I. Data collection of physiological parameters in swine, cattle and sheep.
    Lautz LS; Dorne JLCM; Oldenkamp R; Hendriks AJ; Ragas AMJ
    Toxicol Lett; 2020 Feb; 319():95-101. PubMed ID: 31678400
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling.
    Abduljalil K; Furness P; Johnson TN; Rostami-Hodjegan A; Soltani H
    Clin Pharmacokinet; 2012 Jun; 51(6):365-96. PubMed ID: 22515555
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A workflow example of PBPK modeling to support pediatric research and development: case study with lorazepam.
    Maharaj AR; Barrett JS; Edginton AN
    AAPS J; 2013 Apr; 15(2):455-64. PubMed ID: 23344790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Physiologically based pharmacokinetic models in the prediction of oral drug exposure over the entire pediatric age range-sotalol as a model drug.
    Khalil F; Läer S
    AAPS J; 2014 Mar; 16(2):226-39. PubMed ID: 24399240
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.