These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 33795639)

  • 1. A family harboring an MLKL loss of function variant implicates impaired necroptosis in diabetes.
    Hildebrand JM; Lo B; Tomei S; Mattei V; Young SN; Fitzgibbon C; Murphy JM; Fadda A
    Cell Death Dis; 2021 Apr; 12(4):345. PubMed ID: 33795639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis.
    Meng Y; Davies KA; Fitzgibbon C; Young SN; Garnish SE; Horne CR; Luo C; Garnier JM; Liang LY; Cowan AD; Samson AL; Lessene G; Sandow JJ; Czabotar PE; Murphy JM
    Nat Commun; 2021 Nov; 12(1):6783. PubMed ID: 34811356
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKL.
    Jacobsen AV; Pierotti CL; Lowes KN; Au AE; Zhang Y; Etemadi N; Fitzgibbon C; Kersten WJA; Samson AL; van Delft MF; Huang DCS; Sabroux HJ; Lessene G; Silke J; Murphy JM
    Cell Death Dis; 2022 Apr; 13(4):291. PubMed ID: 35365636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Necroptosis induced by RIPK3 requires MLKL but not Drp1.
    Moujalled DM; Cook WD; Murphy JM; Vaux DL
    Cell Death Dis; 2014 Feb; 5(2):e1086. PubMed ID: 24577084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A cytosolic heat shock protein 90 and co-chaperone p23 complex activates RIPK3/MLKL during necroptosis of endothelial cells in acute respiratory distress syndrome.
    Yu X; Mao M; Liu X; Shen T; Li T; Yu H; Zhang J; Chen X; Zhao X; Zhu D
    J Mol Med (Berl); 2020 Apr; 98(4):569-583. PubMed ID: 32072232
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
    Garnish SE; Meng Y; Koide A; Sandow JJ; Denbaum E; Jacobsen AV; Yeung W; Samson AL; Horne CR; Fitzgibbon C; Young SN; Smith PPC; Webb AI; Petrie EJ; Hildebrand JM; Kannan N; Czabotar PE; Koide S; Murphy JM
    Nat Commun; 2021 Apr; 12(1):2211. PubMed ID: 33850121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Necroptosis inhibitors: mechanisms of action and therapeutic potential.
    Zhou Y; Cai Z; Zhai Y; Yu J; He Q; He Y; Jitkaew S; Cai Z
    Apoptosis; 2024 Feb; 29(1-2):22-44. PubMed ID: 38001341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.
    Faergeman SL; Evans H; Attfield KE; Desel C; Kuttikkatte SB; Sommerlund M; Jensen LT; Frokiaer J; Friese MA; Matthews PM; Luchtenborg C; Brügger B; Oturai AB; Dendrou CA; Fugger L
    Cell Death Dis; 2020 May; 11(5):303. PubMed ID: 32358523
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin.
    Shrestha A; Mehdizadeh Gohari I; McClane BA
    mBio; 2019 Dec; 10(6):. PubMed ID: 31848291
    [No Abstract]   [Full Text] [Related]  

  • 10. Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.
    Rodriguez DA; Weinlich R; Brown S; Guy C; Fitzgerald P; Dillon CP; Oberst A; Quarato G; Low J; Cripps JG; Chen T; Green DR
    Cell Death Differ; 2016 Jan; 23(1):76-88. PubMed ID: 26024392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.
    Tanzer MC; Tripaydonis A; Webb AI; Young SN; Varghese LN; Hall C; Alexander WS; Hildebrand JM; Silke J; Murphy JM
    Biochem J; 2015 Oct; 471(2):255-65. PubMed ID: 26283547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
    Newton K; Wickliffe KE; Dugger DL; Maltzman A; Roose-Girma M; Dohse M; Kőműves L; Webster JD; Dixit VM
    Nature; 2019 Oct; 574(7778):428-431. PubMed ID: 31511692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
    Wang Z; Feng J; Yu J; Chen G
    J Cell Sci; 2019 May; 132(10):. PubMed ID: 31028177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biological events and molecular signaling following MLKL activation during necroptosis.
    Gong YN; Guy C; Crawford JC; Green DR
    Cell Cycle; 2017 Oct; 16(19):1748-1760. PubMed ID: 28854080
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3.
    Lee SY; Kim H; Li CM; Kang J; Najafov A; Jung M; Kang S; Wang S; Yuan J; Jung YK
    Cell Death Dis; 2019 Dec; 10(12):923. PubMed ID: 31801942
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.
    Petrie EJ; Sandow JJ; Lehmann WIL; Liang LY; Coursier D; Young SN; Kersten WJA; Fitzgibbon C; Samson AL; Jacobsen AV; Lowes KN; Au AE; Jousset Sabroux H; Lalaoui N; Webb AI; Lessene G; Manning G; Lucet IS; Murphy JM
    Cell Rep; 2019 Sep; 28(13):3309-3319.e5. PubMed ID: 31553902
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A toolbox for imaging RIPK1, RIPK3, and MLKL in mouse and human cells.
    Samson AL; Fitzgibbon C; Patel KM; Hildebrand JM; Whitehead LW; Rimes JS; Jacobsen AV; Horne CR; Gavin XJ; Young SN; Rogers KL; Hawkins ED; Murphy JM
    Cell Death Differ; 2021 Jul; 28(7):2126-2144. PubMed ID: 33589776
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL.
    Najafov A; Mookhtiar AK; Luu HS; Ordureau A; Pan H; Amin PP; Li Y; Lu Q; Yuan J
    Mol Cell; 2019 Aug; 75(3):457-468.e4. PubMed ID: 31230815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis.
    Zhou T; DeRoo E; Yang H; Stranz A; Wang Q; Ginnan R; Singer HA; Liu B
    Cells; 2021 Sep; 10(9):. PubMed ID: 34572045
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Saracatinib inhibits necroptosis and ameliorates psoriatic inflammation by targeting MLKL.
    Li J; Liu X; Liu Y; Huang F; Liang J; Lin Y; Hu F; Feng J; Han Z; Chen Y; Chen X; Lin Q; Wu L; Li L
    Cell Death Dis; 2024 Feb; 15(2):122. PubMed ID: 38331847
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.