119 related articles for article (PubMed ID: 33798733)
1. The development of novel glucocorticoid receptor antagonists: From rational chemical design to therapeutic efficacy in metabolic disease models.
Kroon J; Viho EMG; Gentenaar M; Koorneef LL; van Kooten C; Rensen PCN; Kooijman S; Hunt H; Meijer OC
Pharmacol Res; 2021 Jun; 168():105588. PubMed ID: 33798733
[TBL] [Abstract][Full Text] [Related]
2. Selective Glucocorticoid Receptor Antagonist CORT125281 Activates Brown Adipose Tissue and Alters Lipid Distribution in Male Mice.
Kroon J; Koorneef LL; van den Heuvel JK; Verzijl CRC; van de Velde NM; Mol IM; Sips HCM; Hunt H; Rensen PCN; Meijer OC
Endocrinology; 2018 Jan; 159(1):535-546. PubMed ID: 28938459
[TBL] [Abstract][Full Text] [Related]
3. The selective glucocorticoid receptor antagonist CORT125281 has tissue-specific activity.
Koorneef LL; Kroon J; Viho EMG; Wahl LF; Heckmans KML; van Dorst MMAR; Hoekstra M; Houtman R; Hunt H; Meijer OC
J Endocrinol; 2020 Jul; 246(1):79-92. PubMed ID: 32369774
[TBL] [Abstract][Full Text] [Related]
4. A novel combined glucocorticoid-mineralocorticoid receptor selective modulator markedly prevents weight gain and fat mass expansion in mice fed a high-fat diet.
Mammi C; Marzolla V; Armani A; Feraco A; Antelmi A; Maslak E; Chlopicki S; Cinti F; Hunt H; Fabbri A; Caprio M
Int J Obes (Lond); 2016 Jun; 40(6):964-72. PubMed ID: 26830012
[TBL] [Abstract][Full Text] [Related]
5. Identification of a selective glucocorticoid receptor modulator that prevents both diet-induced obesity and inflammation.
van den Heuvel JK; Boon MR; van Hengel I; Peschier-van der Put E; van Beek L; van Harmelen V; van Dijk KW; Pereira AM; Hunt H; Belanoff JK; Rensen PC; Meijer OC
Br J Pharmacol; 2016 Jun; 173(11):1793-804. PubMed ID: 26990179
[TBL] [Abstract][Full Text] [Related]
6. Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis.
Campbell JE; Fediuc S; Hawke TJ; Riddell MC
Metabolism; 2009 May; 58(5):651-60. PubMed ID: 19375588
[TBL] [Abstract][Full Text] [Related]
7. Dexamethasone-associated metabolic effects in male mice are partially caused by depletion of endogenous corticosterone.
Koorneef LL; van der Meulen M; Kooijman S; Sánchez-López E; Scheerstra JF; Voorhoeve MC; Ramesh ANN; Rensen PCN; Giera M; Kroon J; Meijer OC
Front Endocrinol (Lausanne); 2022; 13():960279. PubMed ID: 36034417
[TBL] [Abstract][Full Text] [Related]
8. Differential effects of the new glucocorticoid receptor antagonist ORG 34517 and RU486 (mifepristone) on glucocorticoid receptor nuclear translocation in the AtT20 cell line.
Peeters BW; Ruigt GS; Craighead M; Kitchener P
Ann N Y Acad Sci; 2008 Dec; 1148():536-41. PubMed ID: 19120154
[TBL] [Abstract][Full Text] [Related]
9. Androgens modulate glucocorticoid receptor activity in adipose tissue and liver.
Spaanderman DCE; Nixon M; Buurstede JC; Sips HC; Schilperoort M; Kuipers EN; Backer EA; Kooijman S; Rensen PCN; Homer NZM; Walker BR; Meijer OC; Kroon J
J Endocrinol; 2018 Oct; ():. PubMed ID: 30400038
[TBL] [Abstract][Full Text] [Related]
10. FKBP5 mRNA Expression Is a Biomarker for GR Antagonism.
Bali U; Phillips T; Hunt H; Unitt J
J Clin Endocrinol Metab; 2016 Nov; 101(11):4305-4312. PubMed ID: 27459525
[TBL] [Abstract][Full Text] [Related]
11. Increased glycogen synthase kinase-3β and hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to glucocorticoid-induced mouse visceral adiposity.
Yan C; Yang H; Wang Y; Dong Y; Yu F; Wu Y; Wang W; Adaku U; Lutfy K; Friedman TC; Tian S; Liu Y
Int J Obes (Lond); 2016 Aug; 40(8):1233-41. PubMed ID: 27102048
[TBL] [Abstract][Full Text] [Related]
12. Effects of combined glucocorticoid/mineralocorticoid receptor modulation (CORT118335) on energy balance, adiposity, and lipid metabolism in male rats.
Nguyen ET; Berman S; Streicher J; Estrada CM; Caldwell JL; Ghisays V; Ulrich-Lai Y; Solomon MB
Am J Physiol Endocrinol Metab; 2019 Aug; 317(2):E337-E349. PubMed ID: 31112405
[TBL] [Abstract][Full Text] [Related]
13. Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.
Mak TCS; Livingstone DEW; Nixon M; Walker BR; Andrew R
Endocrinology; 2019 Sep; 160(9):2061-2073. PubMed ID: 31199473
[TBL] [Abstract][Full Text] [Related]
14. The novel progesterone receptor antagonists RTI 3021-012 and RTI 3021-022 exhibit complex glucocorticoid receptor antagonist activities: implications for the development of dissociated antiprogestins.
Wagner BL; Pollio G; Giangrande P; Webster JC; Breslin M; Mais DE; Cook CE; Vedeckis WV; Cidlowski JA; McDonnell DP
Endocrinology; 1999 Mar; 140(3):1449-58. PubMed ID: 10067874
[TBL] [Abstract][Full Text] [Related]
15. Adipocyte glucocorticoid receptor is important in lipolysis and insulin resistance due to exogenous steroids, but not insulin resistance caused by high fat feeding.
Shen Y; Roh HC; Kumari M; Rosen ED
Mol Metab; 2017 Oct; 6(10):1150-1160. PubMed ID: 29031716
[TBL] [Abstract][Full Text] [Related]
16. The novel non-steroidal MR antagonist finerenone improves metabolic parameters in high-fat diet-fed mice and activates brown adipose tissue via AMPK-ATGL pathway.
Marzolla V; Feraco A; Gorini S; Mammi C; Marrese C; Mularoni V; Boitani C; Lombès M; Kolkhof P; Ciriolo MR; Armani A; Caprio M
FASEB J; 2020 Sep; 34(9):12450-12465. PubMed ID: 32729974
[TBL] [Abstract][Full Text] [Related]
17. Postnatal glucocorticoid excess due to pituitary glucocorticoid receptor deficiency: differential short- and long-term consequences.
Schmidt MV; Sterlemann V; Wagner K; Niederleitner B; Ganea K; Liebl C; Deussing JM; Berger S; Schütz G; Holsboer F; Müller MB
Endocrinology; 2009 Jun; 150(6):2709-16. PubMed ID: 19213843
[TBL] [Abstract][Full Text] [Related]
18. Glucocorticoid Receptor and Adipocyte Biology.
Lee RA; Harris CA; Wang JC
Nucl Receptor Res; 2018; 5():. PubMed ID: 30310815
[TBL] [Abstract][Full Text] [Related]
19. Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Nguyen Dinh Cat A; Briones AM; Callera GE; Yogi A; He Y; Montezano AC; Touyz RM
Hypertension; 2011 Sep; 58(3):479-88. PubMed ID: 21788604
[TBL] [Abstract][Full Text] [Related]
20. Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633).
Du X; Eksterowicz J; Zhou H; Rew Y; Zhu L; Yan X; Medina JC; Huang T; Chen X; Sutimantanapi D; Jahchan N; Kong W; Sun J; Zavorotinskaya T; Ye Q; Fantin VR; Sun D
J Med Chem; 2019 Jul; 62(14):6751-6764. PubMed ID: 31274313
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
