These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 33804659)

  • 21. Design, crystal structure determination, molecular dynamic simulation and MMGBSA calculations of novel p38-alpha MAPK inhibitors for combating Alzheimer's disease.
    Iqbal S; Potharaju R; Naveen S; Lokanath NK; Mohanakrishnan AK; Gunasekaran K
    J Biomol Struct Dyn; 2022 Aug; 40(13):6114-6127. PubMed ID: 33522434
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors.
    Laufer SA; Domeyer DM; Scior TR; Albrecht W; Hauser DR
    J Med Chem; 2005 Feb; 48(3):710-22. PubMed ID: 15689155
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.
    Laufer SA; Hauser DR; Domeyer DM; Kinkel K; Liedtke AJ
    J Med Chem; 2008 Jul; 51(14):4122-49. PubMed ID: 18578517
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Design, synthesis, and biological evaluation of phenylamino-substituted 6,11-dihydro-dibenzo[b,e]oxepin-11-ones and dibenzo[a,d]cycloheptan-5-ones: novel p38 MAP kinase inhibitors.
    Laufer SA; Ahrens GM; Karcher SC; Hering JS; Niess R
    J Med Chem; 2006 Dec; 49(26):7912-5. PubMed ID: 17181176
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis, p38α MAP kinase inhibition, anti-inflammatory activity, and molecular docking studies of 1,2,4-triazole-based benzothiazole-2-amines.
    Tariq S; Alam O; Amir M
    Arch Pharm (Weinheim); 2018 Apr; 351(3-4):e1700304. PubMed ID: 29611883
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis, evaluation and docking of novel pyrazolo pyrimidines as potent p38α MAP kinase inhibitors with improved anti-inflammatory, ulcerogenic and TNF-α inhibitory properties.
    Somakala K; Tariq S; Amir M
    Bioorg Chem; 2019 Jun; 87():550-559. PubMed ID: 30928877
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Virtual screening based on pharmacophore model followed by docking simulation studies in search of potential inhibitors for p38 map kinase.
    Shahlaei M; Doosti E
    Biomed Pharmacother; 2016 May; 80():352-372. PubMed ID: 27133076
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of an allosteric and Smad3-selective inhibitor of p38αMAPK using a substrate-based approach.
    Nagao H; Kitagawa D; Nakajima F; Sawa M; Kinoshita T
    Bioorg Med Chem Lett; 2021 Jul; 43():128056. PubMed ID: 33892104
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Syntheses and structure-activity relationships for some triazolyl p38α MAPK inhibitors.
    Seerden JP; Leusink-Ionescu G; Leguijt R; Saccavini C; Gelens E; Dros B; Woudenberg-Vrenken T; Molema G; Kamps JA; Kellogg RM
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1352-7. PubMed ID: 24508134
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery and optimization of p38 inhibitors via computer-assisted drug design.
    Goldberg DR; Hao MH; Qian KC; Swinamer AD; Gao DA; Xiong Z; Sarko C; Berry A; Lord J; Magolda RL; Fadra T; Kroe RR; Kukulka A; Madwed JB; Martin L; Pargellis C; Skow D; Song JJ; Tan Z; Torcellini CA; Zimmitti CS; Yee NK; Moss N
    J Med Chem; 2007 Aug; 50(17):4016-26. PubMed ID: 17658737
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.
    Simard JR; Getlik M; Grütter C; Pawar V; Wulfert S; Rabiller M; Rauh D
    J Am Chem Soc; 2009 Sep; 131(37):13286-96. PubMed ID: 19572644
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design, synthesis and SAR of phenylamino-substituted 5,11-dihydro-dibenzo[a,d]cyclohepten-10-ones and 11H-dibenzo[b,f]oxepin-10-ones as p38 MAP kinase inhibitors.
    Dorn A; Schattel V; Laufer S
    Bioorg Med Chem Lett; 2010 May; 20(10):3074-7. PubMed ID: 20418099
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors.
    Hauser DR; Scior T; Domeyer DM; Kammerer B; Laufer SA
    J Med Chem; 2007 May; 50(9):2060-6. PubMed ID: 17411025
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[4,5-b]pyridin-2-one-Based p38 MAP Kinase Inhibitors: Part 1.
    Kaieda A; Takahashi M; Fukuda H; Okamoto R; Morimoto S; Gotoh M; Miyazaki T; Hori Y; Unno S; Kawamoto T; Tanaka T; Itono S; Takagi T; Sugimoto H; Okada K; Snell G; Bertsch R; Nguyen J; Sang BC; Miwatashi S
    ChemMedChem; 2019 May; 14(10):1022-1030. PubMed ID: 30945818
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis, and structure-activity relationships of aminopyridine N-oxides, a novel scaffold for the potent and selective inhibition of p38 mitogen activated protein kinase.
    Lumeras W; Caturla F; Vidal L; Esteve C; Balagué C; Orellana A; Domínguez M; Roca R; Huerta JM; Godessart N; Vidal B
    J Med Chem; 2009 Sep; 52(17):5531-45. PubMed ID: 19678708
    [TBL] [Abstract][Full Text] [Related]  

  • 36. 1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies.
    Tariq S; Kamboj P; Alam O; Amir M
    Bioorg Chem; 2018 Dec; 81():630-641. PubMed ID: 30253336
    [TBL] [Abstract][Full Text] [Related]  

  • 37. From five- to six-membered rings: 3,4-diarylquinolinone as lead for novel p38MAP kinase inhibitors.
    Peifer C; Kinkel K; Abadleh M; Schollmeyer D; Laufer S
    J Med Chem; 2007 Mar; 50(6):1213-21. PubMed ID: 17323937
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Antitumor effects of berberine against EGFR, ERK1/2, P38 and AKT in MDA-MB231 and MCF-7 breast cancer cells using molecular modelling and in vitro study.
    Jabbarzadeh Kaboli P; Leong MP; Ismail P; Ling KH
    Pharmacol Rep; 2019 Feb; 71(1):13-23. PubMed ID: 30343043
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of p38α MAP kinase inhibitors by pharmacophore based virtual screening.
    Gangwal RP; Das NR; Thanki K; Damre MV; Dhoke GV; Sharma SS; Jain S; Sangamwar AT
    J Mol Graph Model; 2014 Apr; 49():18-24. PubMed ID: 24473068
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Aza-analogue dibenzepinone scaffolds as p38 mitogen-activated protein kinase inhibitors: design, synthesis, and biological data of inhibitors with improved physicochemical properties.
    Karcher SC; Laufer SA
    J Med Chem; 2009 Mar; 52(6):1778-82. PubMed ID: 19253982
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.