BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 33806835)

  • 1. Single-Cell Transcriptomics Supports a Role of
    Hoffmann A; Spengler D
    Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33806835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.
    Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM
    Mol Autism; 2017; 8():11. PubMed ID: 28321286
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CHD8 haploinsufficiency links autism to transient alterations in excitatory and inhibitory trajectories.
    Villa CE; Cheroni C; Dotter CP; López-Tóbon A; Oliveira B; Sacco R; Yahya AÇ; Morandell J; Gabriele M; Tavakoli MR; Lyudchik J; Sommer C; Gabitto M; Danzl JG; Testa G; Novarino G
    Cell Rep; 2022 Apr; 39(1):110615. PubMed ID: 35385734
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
    Modafferi S; Zhong X; Kleensang A; Murata Y; Fagiani F; Pamies D; Hogberg HT; Calabrese V; Lachman H; Hartung T; Smirnova L
    Environ Health Perspect; 2021 Jul; 129(7):77001. PubMed ID: 34259569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Autism-associated CHD8 keeps proliferation of human neural progenitors in check by lengthening the G1 phase of the cell cycle.
    Coakley-Youngs E; Ranatunga M; Richardson S; Getti G; Shorter S; Fivaz M
    Biol Open; 2022 Sep; 11(9):. PubMed ID: 36222238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.
    Sugathan A; Biagioli M; Golzio C; Erdin S; Blumenthal I; Manavalan P; Ragavendran A; Brand H; Lucente D; Miles J; Sheridan SD; Stortchevoi A; Kellis M; Haggarty SJ; Katsanis N; Gusella JF; Talkowski ME
    Proc Natl Acad Sci U S A; 2014 Oct; 111(42):E4468-77. PubMed ID: 25294932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants.
    Siu MT; Butcher DT; Turinsky AL; Cytrynbaum C; Stavropoulos DJ; Walker S; Caluseriu O; Carter M; Lou Y; Nicolson R; Georgiades S; Szatmari P; Anagnostou E; Scherer SW; Choufani S; Brudno M; Weksberg R
    Clin Epigenetics; 2019 Jul; 11(1):103. PubMed ID: 31311581
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.
    Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE
    Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.
    Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP
    Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes.
    Wilkinson B; Grepo N; Thompson BL; Kim J; Wang K; Evgrafov OV; Lu W; Knowles JA; Campbell DB
    Transl Psychiatry; 2015 May; 5(5):e568. PubMed ID: 25989142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons.
    Xu Q; Liu YY; Wang X; Tan GH; Li HP; Hulbert SW; Li CY; Hu CC; Xiong ZQ; Xu X; Jiang YH
    Mol Autism; 2018; 9():65. PubMed ID: 30574290
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons.
    Kawamura A; Nishiyama M
    Commun Biol; 2023 Jun; 6(1):593. PubMed ID: 37268684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1.
    Haddad Derafshi B; Danko T; Chanda S; Batista PJ; Litzenburger U; Lee QY; Ng YH; Sebin A; Chang HY; Südhof TC; Wernig M
    Sci Rep; 2022 Dec; 12(1):22425. PubMed ID: 36575212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHD8 intragenic deletion associated with autism spectrum disorder.
    Stolerman ES; Smith B; Chaubey A; Jones JR
    Eur J Med Genet; 2016 Apr; 59(4):189-94. PubMed ID: 26921529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review.
    Merner N; Forgeot d'Arc B; Bell SC; Maussion G; Peng H; Gauthier J; Crapper L; Hamdan FF; Michaud JL; Mottron L; Rouleau GA; Ernst C
    Am J Med Genet A; 2016 May; 170A(5):1225-35. PubMed ID: 26789910
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CHD8 haploinsufficiency results in autistic-like phenotypes in mice.
    Katayama Y; Nishiyama M; Shoji H; Ohkawa Y; Kawamura A; Sato T; Suyama M; Takumi T; Miyakawa T; Nakayama KI
    Nature; 2016 Sep; 537(7622):675-679. PubMed ID: 27602517
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Progress in autism: de novo mutation and CHD8 functions].
    Xiong XX; He M; Chen XQ
    Sheng Li Ke Xue Jin Zhan; 2014 Jun; 45(3):185-9. PubMed ID: 25219269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation.
    Sood S; Weber CM; Hodges HC; Krokhotin A; Shalizi A; Crabtree GR
    Proc Natl Acad Sci U S A; 2020 Sep; 117(36):22331-22340. PubMed ID: 32839322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.
    Platt RJ; Zhou Y; Slaymaker IM; Shetty AS; Weisbach NR; Kim JA; Sharma J; Desai M; Sood S; Kempton HR; Crabtree GR; Feng G; Zhang F
    Cell Rep; 2017 Apr; 19(2):335-350. PubMed ID: 28402856
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concurrent Developmental Regression and Neurocognitive Decline in a Child With De Novo CHD8 Gene Mutation.
    Paik KE; Mooneyham GC
    Pediatr Neurol; 2024 May; 154():1-3. PubMed ID: 38428335
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.