251 related articles for article (PubMed ID: 33807988)
1. Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates-A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics.
Taroncher-Oldenburg G; Müller C; Obermann W; Ziebuhr J; Hartmann RK; Grünweller A
Microorganisms; 2021 Mar; 9(3):. PubMed ID: 33807988
[TBL] [Abstract][Full Text] [Related]
2. Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity.
Obermann W; Friedrich A; Madhugiri R; Klemm P; Mengel JP; Hain T; Pleschka S; Wendel HG; Hartmann RK; Schiffmann S; Ziebuhr J; Müller C; Grünweller A
Viruses; 2022 Mar; 14(3):. PubMed ID: 35336926
[TBL] [Abstract][Full Text] [Related]
3. Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.
Müller C; Obermann W; Schulte FW; Lange-Grünweller K; Oestereich L; Elgner F; Glitscher M; Hildt E; Singh K; Wendel HG; Hartmann RK; Ziebuhr J; Grünweller A
Antiviral Res; 2020 Mar; 175():104706. PubMed ID: 31931103
[TBL] [Abstract][Full Text] [Related]
4. Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor.
Iwasaki S; Floor SN; Ingolia NT
Nature; 2016 Jun; 534(7608):558-61. PubMed ID: 27309803
[TBL] [Abstract][Full Text] [Related]
5. Comparing the Effects of Rocaglates on Energy Metabolism and Immune Modulation on Cells of the Human Immune System.
Schiffmann S; Henke M; Seifert M; Ulshöfer T; Roser LA; Magari F; Wendel HG; Grünweller A; Parnham MJ
Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982945
[TBL] [Abstract][Full Text] [Related]
6. Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.
Müller C; Schulte FW; Lange-Grünweller K; Obermann W; Madhugiri R; Pleschka S; Ziebuhr J; Hartmann RK; Grünweller A
Antiviral Res; 2018 Feb; 150():123-129. PubMed ID: 29258862
[TBL] [Abstract][Full Text] [Related]
7. The natural compound silvestrol is a potent inhibitor of Ebola virus replication.
Biedenkopf N; Lange-Grünweller K; Schulte FW; Weißer A; Müller C; Becker D; Becker S; Hartmann RK; Grünweller A
Antiviral Res; 2017 Jan; 137():76-81. PubMed ID: 27864075
[TBL] [Abstract][Full Text] [Related]
8. Comparative phytochemistry of flavaglines (= rocaglamides), a group of highly bioactive flavolignans from
Greger H
Phytochem Rev; 2022; 21(3):725-764. PubMed ID: 34104125
[TBL] [Abstract][Full Text] [Related]
9. Exploring the targeting spectrum of rocaglates among eIF4A homologs.
Naineni SK; Cencic R; Robert F; Brown LE; Haque M; Scott-Talib J; Sénéchal P; Schmeing TM; Porco JA; Pelletier J
RNA; 2023 Jun; 29(6):826-835. PubMed ID: 36882295
[TBL] [Abstract][Full Text] [Related]
10. Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.
Obermann W; Azri MFD; Konopka L; Schmidt N; Magari F; Sherman J; Silva LMR; Hermosilla C; Ludewig AH; Houhou H; Haeberlein S; Luo MY; Häcker I; Schetelig MF; Grevelding CG; Schroeder FC; Lau GSK; Taubert A; Rodriguez A; Heine A; Yeo TC; Grünweller A; Taroncher-Oldenburg G
Sci Rep; 2023 Jun; 13(1):9297. PubMed ID: 37291191
[TBL] [Abstract][Full Text] [Related]
11. Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.
Chu J; Zhang W; Cencic R; Devine WG; Beglov D; Henkel T; Brown LE; Vajda S; Porco JA; Pelletier J
Cell Chem Biol; 2019 Nov; 26(11):1586-1593.e3. PubMed ID: 31519508
[TBL] [Abstract][Full Text] [Related]
12. eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G.
Sen ND; Zhou F; Harris MS; Ingolia NT; Hinnebusch AG
Proc Natl Acad Sci U S A; 2016 Sep; 113(38):10464-72. PubMed ID: 27601676
[TBL] [Abstract][Full Text] [Related]
13. Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo.
Gulay S; Gupta N; Lorsch JR; Hinnebusch AG
Elife; 2020 May; 9():. PubMed ID: 32469309
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of Zika Virus Replication by Silvestrol.
Elgner F; Sabino C; Basic M; Ploen D; Grünweller A; Hildt E
Viruses; 2018 Mar; 10(4):. PubMed ID: 29584632
[TBL] [Abstract][Full Text] [Related]
15. Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication.
Slaine PD; Kleer M; Smith NK; Khaperskyy DA; McCormick C
Viruses; 2017 Dec; 9(12):. PubMed ID: 29258238
[TBL] [Abstract][Full Text] [Related]
16. A parasitic fungus employs mutated eIF4A to survive on rocaglate-synthesizing
Chen M; Kumakura N; Saito H; Muller R; Nishimoto M; Mito M; Gan P; Ingolia NT; Shirasu K; Ito T; Shichino Y; Iwasaki S
Elife; 2023 Feb; 12():. PubMed ID: 36852480
[TBL] [Abstract][Full Text] [Related]
17. Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F.
Chu J; Zhang W; Cencic R; O'Connor PBF; Robert F; Devine WG; Selznick A; Henkel T; Merrick WC; Brown LE; Baranov PV; Porco JA; Pelletier J
Cell Rep; 2020 Feb; 30(8):2481-2488.e5. PubMed ID: 32101697
[TBL] [Abstract][Full Text] [Related]
18. Eukaryotic initiation factor 4A (eIF4A) during viral infections.
Montero H; Pérez-Gil G; Sampieri CL
Virus Genes; 2019 Jun; 55(3):267-273. PubMed ID: 30796742
[TBL] [Abstract][Full Text] [Related]
19. Translation Inhibition by Rocaglates Is Independent of eIF4E Phosphorylation Status.
Chu J; Cencic R; Wang W; Porco JA; Pelletier J
Mol Cancer Ther; 2016 Jan; 15(1):136-41. PubMed ID: 26586722
[TBL] [Abstract][Full Text] [Related]
20. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Nguyen TM; Kabotyanski EB; Dou Y; Reineke LC; Zhang P; Zhang XH; Malovannaya A; Jung SY; Mo Q; Roarty KP; Chen Y; Zhang B; Neilson JR; Lloyd RE; Perou CM; Ellis MJ; Rosen JM
Cancer Res; 2018 Aug; 78(15):4229-4240. PubMed ID: 29844125
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]