328 related articles for article (PubMed ID: 33809771)
1. Novel Donepezil-Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer's Disease.
Queda F; Calò S; Gwizdala K; Magalhães JD; Cardoso SM; Chaves S; Piemontese L; Santos MA
Molecules; 2021 Mar; 26(6):. PubMed ID: 33809771
[TBL] [Abstract][Full Text] [Related]
2. Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
Chaves S; Resta S; Rinaldo F; Costa M; Josselin R; Gwizdala K; Piemontese L; Capriati V; Pereira-Santos AR; Cardoso SM; Santos MA
Molecules; 2020 Feb; 25(4):. PubMed ID: 32098407
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Dias Viegas FP; de Freitas Silva M; Divino da Rocha M; Castelli MR; Riquiel MM; Machado RP; Vaz SM; Simões de Lima LM; Mancini KC; Marques de Oliveira PC; Morais ÉP; Gontijo VS; da Silva FMR; D'Alincourt da Fonseca Peçanha D; Castro NG; Neves GA; Giusti-Paiva A; Vilela FC; Orlandi L; Camps I; Veloso MP; Leomil Coelho LF; Ionta M; Ferreira-Silva GÁ; Pereira RM; Dardenne LE; Guedes IA; de Oliveira Carneiro Junior W; Quaglio Bellozi PM; Pinheiro de Oliveira AC; Ferreira FF; Pruccoli L; Tarozzi A; Viegas C
Eur J Med Chem; 2018 Mar; 147():48-65. PubMed ID: 29421570
[TBL] [Abstract][Full Text] [Related]
4. Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease.
Mezeiova E; Chalupova K; Nepovimova E; Gorecki L; Prchal L; Malinak D; Kuca K; Soukup O; Korabecny J
Curr Alzheimer Res; 2019; 16(9):772-800. PubMed ID: 30819078
[TBL] [Abstract][Full Text] [Related]
5. Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer's drug candidates.
Piemontese L; Tomás D; Hiremathad A; Capriati V; Candeias E; Cardoso SM; Chaves S; Santos MA
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1212-1224. PubMed ID: 30160188
[TBL] [Abstract][Full Text] [Related]
6. Metformin and its sulphonamide derivative simultaneously potentiateanti-cholinesterase activity of donepezil and inhibit beta-amyloid aggregation.
Markowicz-Piasecka M; Huttunen KM; Sikora J
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1309-1322. PubMed ID: 30251898
[TBL] [Abstract][Full Text] [Related]
7. Donepezil-butylated hydroxytoluene (BHT) hybrids as Anti-Alzheimer's disease agents with cholinergic, antioxidant, and neuroprotective properties.
Cai P; Fang SQ; Yang HL; Yang XL; Liu QH; Kong LY; Wang XB
Eur J Med Chem; 2018 Sep; 157():161-176. PubMed ID: 30096650
[TBL] [Abstract][Full Text] [Related]
8. The development of advanced structural framework as multi-target-directed ligands for the treatment of Alzheimer's disease.
Sang Z; Wang K; Shi J; Liu W; Cheng X; Zhu G; Wang Y; Zhao Y; Qiao Z; Wu A; Tan Z
Eur J Med Chem; 2020 Apr; 192():112180. PubMed ID: 32131034
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
[TBL] [Abstract][Full Text] [Related]
10. Design, Synthesis, and Biological Evaluation of Piperazine and
Waiker DK; Verma A; Akhilesh ; A GT; Singh N; Roy A; Dilnashin H; Tiwari V; Trigun SK; Singh SP; Krishnamurthy S; Lama P; Davisson VJ; Shrivastava SK
ACS Chem Neurosci; 2023 Jun; 14(11):2217-2242. PubMed ID: 37216500
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of novel N-Benzyl piperidine derivatives as potent HDAC/AChE inhibitors for Alzheimer's disease.
Qin P; Ran Y; Xie F; Liu Y; Wei C; Luan X; Wu J
Bioorg Med Chem; 2023 Feb; 80():117178. PubMed ID: 36706609
[TBL] [Abstract][Full Text] [Related]
12. New phosphazine and phosphazide derivatives as multifunctional ligands targeting acetylcholinesterase and β-Amyloid aggregation for treatment of Alzheimer's disease.
El-Sayed NF; El-Hussieny M; Ewies EF; Fouad MA; Boulos LS
Bioorg Chem; 2020 Jan; 95():103499. PubMed ID: 31838287
[TBL] [Abstract][Full Text] [Related]
13. Novel inhibitors of AChE and Aβ aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease.
Liu Y; Uras G; Onuwaje I; Li W; Yao H; Xu S; Li X; Li X; Phillips J; Allen S; Gong Q; Zhang H; Zhu Z; Liu J; Xu J
Eur J Med Chem; 2022 May; 235():114305. PubMed ID: 35339839
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, in vitro evaluation and molecular docking of a new class of indolylpropyl benzamidopiperazines as dual AChE and SERT ligands for Alzheimer's disease.
Rodríguez-Lavado J; Gallardo-Garrido C; Mallea M; Bustos V; Osorio R; Hödar-Salazar M; Chung H; Araya-Maturana R; Lorca M; Pessoa-Mahana CD; Mella-Raipán J; Saitz C; Jaque P; Reyes-Parada M; Iturriaga-Vásquez P; Pessoa-Mahana H
Eur J Med Chem; 2020 Jul; 198():112368. PubMed ID: 32388114
[TBL] [Abstract][Full Text] [Related]
15. Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization.
Costa M; Josselin R; Silva DF; Cardoso SM; May NV; Chaves S; Santos MA
J Inorg Biochem; 2020 May; 206():111039. PubMed ID: 32171933
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel hybrids containing clioquinol-1-benzyl-1,2,3,6-tetrahydropyridine as multi-target-directed ligands (MTDLs) against Alzheimer's disease.
Li X; Li T; Zhang P; Li X; Lu L; Sun Y; Zhang B; Allen S; White L; Phillips J; Zhu Z; Yao H; Xu J
Eur J Med Chem; 2022 Dec; 244():114841. PubMed ID: 36257284
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi-targeted agents to treat Alzheimer's disease.
Meena P; Nemaysh V; Khatri M; Manral A; Luthra PM; Tiwari M
Bioorg Med Chem; 2015 Mar; 23(5):1135-48. PubMed ID: 25624107
[TBL] [Abstract][Full Text] [Related]
18. Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.
Li Q; He S; Chen Y; Feng F; Qu W; Sun H
Eur J Med Chem; 2018 Oct; 158():463-477. PubMed ID: 30243151
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.
Yan J; Hu J; Liu A; He L; Li X; Wei H
Bioorg Med Chem; 2017 Jun; 25(12):2946-2955. PubMed ID: 28454848
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]