BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 33811107)

  • 1. Pharmacokinetic and Biochemical Profiling of Sodium Dichloroacetate in Pregnant Ewes and Fetuses.
    Joseph S; Sharma A; Horne LP; Wood CE; Langaee T; James MO; Stacpoole PW; Keller-Wood M
    Drug Metab Dispos; 2020 Jun; 49(6):451-458. PubMed ID: 33811107
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sodium dichloroacetate stimulates cardiac mitochondrial metabolism and improves cardiac conduction in the ovine fetus during labor.
    Joseph S; Li M; Zhang S; Horne L; Stacpoole PW; Wohlgemuth SE; Edison AS; Wood C; Keller-Wood M
    Am J Physiol Regul Integr Comp Physiol; 2022 Jan; 322(1):R83-R98. PubMed ID: 34851727
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Model Informed Dose Optimization of Dichloroacetate for the Treatment of Congenital Lactic Acidosis in Children.
    Mangal N; James MO; Stacpoole PW; Schmidt S
    J Clin Pharmacol; 2018 Feb; 58(2):212-220. PubMed ID: 28914978
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amelioration of lactic acidosis with dichloroacetate during liver transplantation in humans.
    Shangraw RE; Winter R; Hromco J; Robinson ST; Gallaher EJ
    Anesthesiology; 1994 Nov; 81(5):1127-38. PubMed ID: 7978471
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exposure of Rats to Multiple Oral Doses of Dichloroacetate Results in Upregulation of Hepatic Glutathione Transferases and NAD(P)H Dehydrogenase [Quinone] 1.
    Squirewell EJ; Mareus R; Horne LP; Stacpoole PW; James MO
    Drug Metab Dispos; 2020 Nov; 48(11):1224-1230. PubMed ID: 32873592
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.
    James MO; Jahn SC; Zhong G; Smeltz MG; Hu Z; Stacpoole PW
    Pharmacol Ther; 2017 Feb; 170():166-180. PubMed ID: 27771434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A physiological increase in maternal cortisol alters uteroplacental metabolism in the pregnant ewe.
    Vaughan OR; Davies KL; Ward JW; de Blasio MJ; Fowden AL
    J Physiol; 2016 Nov; 594(21):6407-6418. PubMed ID: 27292274
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of Multiple Doses of Dichloroacetate on GSTZ1 Expression and Activity in Liver and Extrahepatic Tissues of Young and Adult Rats.
    Squirewell EJ; Smeltz MG; Rowland-Faux L; Horne LP; Stacpoole PW; James MO
    Drug Metab Dispos; 2020 Nov; 48(11):1217-1223. PubMed ID: 32873593
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dichloroacetate for lactic acidosis in severe malaria: a pharmacokinetic and pharmacodynamic assessment.
    Krishna S; Supanaranond W; Pukrittayakamee S; Karter D; Supputamongkol Y; Davis TM; Holloway PA; White NJ
    Metabolism; 1994 Aug; 43(8):974-81. PubMed ID: 8052155
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of restriction of placental growth on fetal and utero-placental metabolism.
    Owens JA; Falconer J; Robinson JS
    J Dev Physiol; 1987 Jun; 9(3):225-38. PubMed ID: 3611639
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial Glutathione Transferase Zeta 1 Is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver.
    Smeltz MG; Hu Z; Zhong G; Jahn SC; Rowland-Faux L; Horne LP; Stacpoole PW; James MO
    Chem Res Toxicol; 2019 Oct; 32(10):2042-2052. PubMed ID: 31524376
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of various doses of sodium dichloroacetate on hyperlactatemia in fed ischemic rats.
    Dimlich RV; Kaplan J; Timerding BL; Van Ligten PF
    Ann Emerg Med; 1989 Nov; 18(11):1162-71. PubMed ID: 2683899
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The disposition and effects of two doses of dichloroacetate in adults with severe falciparum malaria.
    Krishna S; Supanaranond W; Pukrittayakamee S; Kuile FT; Ruprah M; White NJ
    Br J Clin Pharmacol; 1996 Jan; 41(1):29-34. PubMed ID: 8824690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.
    Shroads AL; Coats BS; McDonough CW; Langaee T; Stacpoole PW
    J Clin Pharmacol; 2015 Jan; 55(1):50-5. PubMed ID: 25079374
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficacy of dichloroacetate as a lactate-lowering drug.
    Stacpoole PW; Nagaraja NV; Hutson AD
    J Clin Pharmacol; 2003 Jul; 43(7):683-91. PubMed ID: 12856382
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children.
    Stacpoole PW; Kerr DS; Barnes C; Bunch ST; Carney PR; Fennell EM; Felitsyn NM; Gilmore RL; Greer M; Henderson GN; Hutson AD; Neiberger RE; O'Brien RG; Perkins LA; Quisling RG; Shroads AL; Shuster JJ; Silverstein JH; Theriaque DW; Valenstein E
    Pediatrics; 2006 May; 117(5):1519-31. PubMed ID: 16651305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The use of dichloroacetate in the treatment of overwhelming hypoxic acidosis.
    Wahr JA; Ullrich K; Bolling SF
    J Cardiothorac Vasc Anesth; 1994 Feb; 8(1):64-9. PubMed ID: 8167289
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    Tian DD; Bennett SK; Coupland LA; Forwood K; Lwin Y; Pooryousef N; Tea I; Truong TT; Neeman T; Crispin P; D'Rozario J; Blackburn AC
    Pharmacol Res Perspect; 2019 Dec; 7(6):e00526. PubMed ID: 31624634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of dichloroacetate in the treatment of hypoxic lactic acidosis in dogs.
    Graf H; Leach W; Arieff AI
    J Clin Invest; 1985 Sep; 76(3):919-23. PubMed ID: 4044835
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Age-related differences in the effect of dichloroacetate on postischemic lactate and acid clearance measured in vivo using magnetic resonance spectroscopy and microdialysis.
    Corbett R; Laptook A; Gee J; Garcia D; Silmon S; Tollefsbol G
    J Neurochem; 1998 Sep; 71(3):1205-14. PubMed ID: 9721746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.