135 related articles for article (PubMed ID: 33829766)
1. Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Kholodar SA; Finer-Moore JS; Świderek K; Arafet K; Moliner V; Stroud RM; Kohen A
Biochemistry; 2021 Apr; 60(16):1243-1247. PubMed ID: 33829766
[TBL] [Abstract][Full Text] [Related]
2. Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase.
Stull FW; Bernard SM; Sapra A; Smith JL; Zuiderweg ER; Palfey BA
Biochemistry; 2016 Jun; 55(23):3261-9. PubMed ID: 27214228
[TBL] [Abstract][Full Text] [Related]
3. Structural Comparison of
Pozzi C; Ferrari S; Luciani R; Tassone G; Costi MP; Mangani S
Molecules; 2019 Mar; 24(7):. PubMed ID: 30935102
[TBL] [Abstract][Full Text] [Related]
4. Crystal structures of thymidylate synthase mutant R166Q: structural basis for the nearly complete loss of catalytic activity.
Sotelo-Mundo RR; Changchien L; Maley F; Montfort WR
J Biochem Mol Toxicol; 2006; 20(2):88-92. PubMed ID: 16615077
[TBL] [Abstract][Full Text] [Related]
5. The general base in the thymidylate synthase catalyzed proton abstraction.
Ghosh AK; Islam Z; Krueger J; Abeysinghe T; Kohen A
Phys Chem Chem Phys; 2015 Dec; 17(46):30867-75. PubMed ID: 25912171
[TBL] [Abstract][Full Text] [Related]
6. The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.
Stout TJ; Stroud RM
Structure; 1996 Jan; 4(1):67-77. PubMed ID: 8805515
[TBL] [Abstract][Full Text] [Related]
7. Binding of the anticancer drug ZD1694 to E. coli thymidylate synthase: assessing specificity and affinity.
Rutenber EE; Stroud RM
Structure; 1996 Nov; 4(11):1317-24. PubMed ID: 8939755
[TBL] [Abstract][Full Text] [Related]
8. Asparagine 229 mutants of thymidylate synthase catalyze the methylation of 3-methyl-2'-deoxyuridine 5'-monophosphate.
Costi PM; Liu L; Finer-Moore JS; Stroud RM; Santi DV
Biochemistry; 1996 Apr; 35(13):3944-9. PubMed ID: 8672425
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Almog R; Waddling CA; Maley F; Maley GF; Van Roey P
Protein Sci; 2001 May; 10(5):988-96. PubMed ID: 11316879
[TBL] [Abstract][Full Text] [Related]
10. Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Finer-Moore JS; Liu L; Schafmeister CE; Birdsall DL; Mau T; Santi DV; Stroud RM
Biochemistry; 1996 Apr; 35(16):5125-36. PubMed ID: 8611496
[TBL] [Abstract][Full Text] [Related]
11. Crystal structures of a marginally active thymidylate synthase mutant, Arg 126-->Glu.
Strop P; Changchien L; Maley F; Montfort WR
Protein Sci; 1997 Dec; 6(12):2504-11. PubMed ID: 9416600
[TBL] [Abstract][Full Text] [Related]
12. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261.
Newby Z; Lee TT; Morse RJ; Liu Y; Liu L; Venkatraman P; Santi DV; Finer-Moore JS; Stroud RM
Biochemistry; 2006 Jun; 45(24):7415-28. PubMed ID: 16768437
[TBL] [Abstract][Full Text] [Related]
13. Role of the conserved tryptophan 82 of Lactobacillus casei thymidylate synthase.
Kealey JT; Eckstein J; Santi DV
Chem Biol; 1995 Sep; 2(9):609-14. PubMed ID: 9383465
[TBL] [Abstract][Full Text] [Related]
14. Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates.
Deschamps P; Réty S; Bareille J; Leulliot N
Acta Crystallogr F Struct Biol Commun; 2017 Jun; 73(Pt 6):336-341. PubMed ID: 28580921
[TBL] [Abstract][Full Text] [Related]
15. Isolation of a covalent steady-state intermediate in glutamate 60 mutants of thymidylate synthase.
Huang W; Santi DV
J Biol Chem; 1994 Dec; 269(50):31327-9. PubMed ID: 7989294
[TBL] [Abstract][Full Text] [Related]
16. Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase.
Finer-Moore JS; Fauman EB; Morse RJ; Santi DV; Stroud RM
Protein Eng; 1996 Jan; 9(1):69-75. PubMed ID: 9053905
[TBL] [Abstract][Full Text] [Related]
17. Aspartate 221 of thymidylate synthase is involved in folate cofactor binding and in catalysis.
Chiericatti G; Santi DV
Biochemistry; 1998 Jun; 37(25):9038-42. PubMed ID: 9636048
[TBL] [Abstract][Full Text] [Related]
18. The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits.
Anderson AC; O'Neil RH; DeLano WL; Stroud RM
Biochemistry; 1999 Oct; 38(42):13829-36. PubMed ID: 10529228
[TBL] [Abstract][Full Text] [Related]
19. Widespread Perturbation of Function, Structure, and Dynamics by a Conservative Single-Atom Substitution in Thymidylate Synthase.
Sapienza PJ; Lee AL
Biochemistry; 2016 Oct; 55(40):5702-5713. PubMed ID: 27649373
[TBL] [Abstract][Full Text] [Related]
20. A novel dCMP methylase by engineering thymidylate synthase.
Agarwalla S; LaPorte S; Liu L; Finer-Moore J; Stroud RM; Santi DV
Biochemistry; 1997 Dec; 36(50):15909-17. PubMed ID: 9398324
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
