BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 33843112)

  • 1. Insights into modular polyketide synthase loops aided by repetitive sequences.
    Hirsch M; Kumru K; Desai RR; Fitzgerald BJ; Miyazawa T; Ray KA; Saif N; Spears S; Keatinge-Clay AT
    Proteins; 2021 Sep; 89(9):1099-1110. PubMed ID: 33843112
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for selectivity in a highly reducing type II polyketide synthase.
    Du D; Katsuyama Y; Horiuchi M; Fushinobu S; Chen A; Davis TD; Burkart MD; Ohnishi Y
    Nat Chem Biol; 2020 Jul; 16(7):776-782. PubMed ID: 32367018
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.
    Bruegger J; Haushalter RW; Vagstad AL; Shakya G; Mih N; Townsend CA; Burkart MD; Tsai SC
    Chem Biol; 2013 Sep; 20(9):1135-46. PubMed ID: 23993461
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Type I polyketide synthases that require discrete acyltransferases.
    Cheng YQ; Coughlin JM; Lim SK; Shen B
    Methods Enzymol; 2009; 459():165-86. PubMed ID: 19362640
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polyketide Synthase Modules Redefined.
    Keatinge-Clay AT
    Angew Chem Int Ed Engl; 2017 Apr; 56(17):4658-4660. PubMed ID: 28322495
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
    Tang L; Yoon YJ; Choi CY; Hutchinson CR
    Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.
    Chen AY; Schnarr NA; Kim CY; Cane DE; Khosla C
    J Am Chem Soc; 2006 Mar; 128(9):3067-74. PubMed ID: 16506788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis.
    Vuksanovic N; Zhu X; Serrano DA; Siitonen V; Metsä-Ketelä M; Melançon CE; Silvaggi NR
    Acta Crystallogr F Struct Biol Commun; 2020 Aug; 76(Pt 8):372-383. PubMed ID: 32744249
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression and characterization of polyketide synthase module involved in the late step of cephabacin biosynthesis from Lysobacter lactamgenus.
    Lee JS; Vladimirova MG; Demirev AV; Kim BG; Lim SK; Nam DH
    J Microbiol Biotechnol; 2008 Mar; 18(3):427-33. PubMed ID: 18388458
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis.
    Carpenter SM; Williams GJ
    ACS Chem Biol; 2018 Dec; 13(12):3361-3373. PubMed ID: 30484625
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for a protein-protein interaction motif on an acyl carrier protein domain from a modular polyketide synthase.
    Weissman KJ; Hong H; Popovic B; Meersman F
    Chem Biol; 2006 Jun; 13(6):625-36. PubMed ID: 16793520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rational engineering acyltransferase domain of modular polyketide synthase for expanding substrate specificity.
    Zhang W; Zhou L; Li C; Deng Z; Qu X
    Methods Enzymol; 2019; 622():271-292. PubMed ID: 31155056
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli.
    Cummings M; Peters AD; Whitehead GFS; Menon BRK; Micklefield J; Webb SJ; Takano E
    PLoS Biol; 2019 Jul; 17(7):e3000347. PubMed ID: 31318855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase.
    Kapur S; Chen AY; Cane DE; Khosla C
    Proc Natl Acad Sci U S A; 2010 Dec; 107(51):22066-71. PubMed ID: 21127271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G; Anand S; Mohanty D
    J Biomol Struct Dyn; 2013; 31(1):17-29. PubMed ID: 22803697
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY; Alekseyev VY; Chen AY; Tang Y; Cane DE; Khosla C
    Biochemistry; 2004 Nov; 43(44):13892-8. PubMed ID: 15518537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chimeric 6-methylsalicylic acid synthase with domains of acyl carrier protein and methyltransferase from Pseudallescheria boydii shows novel biosynthetic activity.
    Liao JL; Pang KL; Sun GH; Pai TW; Hsu PH; Lin JS; Sun KH; Hsieh CC; Tang SJ
    Microb Biotechnol; 2019 Sep; 12(5):920-931. PubMed ID: 31199579
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
    Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
    J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins.
    Jenner M; Afonso JP; Kohlhaas C; Karbaum P; Frank S; Piel J; Oldham NJ
    Chem Commun (Camb); 2016 Apr; 52(30):5262-5. PubMed ID: 27003309
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.