These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 33844493)

  • 1. Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters.
    Santra S; Kortagere S; Vedachalam S; Gogoi S; Antonio T; Reith MEA; Dutta AK
    ACS Chem Neurosci; 2021 Apr; 12(8):1406-1418. PubMed ID: 33844493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
    Zhang S; Fernandez F; Hazeldine S; Deschamps J; Zhen J; Reith ME; Dutta AK
    J Med Chem; 2006 Jul; 49(14):4239-47. PubMed ID: 16821783
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template.
    Santra S; Sharma H; Vedachalam S; Antonio T; Reith M; Dutta A
    Bioorg Med Chem; 2015 Feb; 23(4):821-8. PubMed ID: 25593099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.
    Zhang S; Zhen J; Reith ME; Dutta AK
    J Med Chem; 2005 Jul; 48(15):4962-71. PubMed ID: 16033275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural exploration of (3S,6S)-6-benzhydryl-N-benzyltetrahydro-2H-pyran-3-amine analogues: identification of potent triple monoamine reuptake inhibitors as potential antidepressants.
    Santra S; Gogoi S; Gopishetty B; Antonio T; Zhen J; Reith ME; Dutta AK
    ChemMedChem; 2012 Dec; 7(12):2093-100. PubMed ID: 23060293
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
    Dutta AK; Santra S; Sharma H; Voshavar C; Xu L; Mabrouk O; Antonio T; Reith ME
    PLoS One; 2014; 9(11):e113420. PubMed ID: 25427177
    [TBL] [Abstract][Full Text] [Related]  

  • 7. D-161, a novel pyran-based triple monoamine transporter blocker: behavioral pharmacological evidence for antidepressant-like action.
    Dutta AK; Ghosh B; Biswas S; Reith ME
    Eur J Pharmacol; 2008 Jul; 589(1-3):73-9. PubMed ID: 18561912
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model.
    Sharma H; Santra S; Debnath J; Antonio T; Reith M; Dutta A
    Bioorg Med Chem; 2014 Jan; 22(1):311-24. PubMed ID: 24315194
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.
    Gopishetty B; Hazeldine S; Santra S; Johnson M; Modi G; Ali S; Zhen J; Reith M; Dutta A
    J Med Chem; 2011 Apr; 54(8):2924-32. PubMed ID: 21446715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural requirements for 2,4- and 3,6-disubstituted pyran biomimetics of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine compounds to interact with monoamine transporters.
    Zhang S; Zhen J; Reith ME; Dutta AK
    Bioorg Med Chem; 2004 Dec; 12(23):6301-15. PubMed ID: 15519172
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel conformationally constrained tropane analogues by 6-endo-trig radical cyclization and stille coupling - switch of activity toward the serotonin and/or norepinephrine transporter.
    Hoepping A; Johnson KM; George C; Flippen-Anderson J; Kozikowski AP
    J Med Chem; 2000 May; 43(10):2064-71. PubMed ID: 10821718
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity.
    Miller GM; Yatin SM; De La Garza R; Goulet M; Madras BK
    Brain Res Mol Brain Res; 2001 Feb; 87(1):124-43. PubMed ID: 11223167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters.
    Kharkar PS; Batman AM; Zhen J; Beardsley PM; Reith ME; Dutta AK
    ChemMedChem; 2009 Jul; 4(7):1075-85. PubMed ID: 19449323
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine.
    Kolhatkar RB; Ghorai SK; George C; Reith ME; Dutta AK
    J Med Chem; 2003 May; 46(11):2205-15. PubMed ID: 12747792
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
    Kolhatkar R; Cook CD; Ghorai SK; Deschamps J; Beardsley PM; Reith ME; Dutta AK
    J Med Chem; 2004 Oct; 47(21):5101-13. PubMed ID: 15456254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 2-Aminoindan and its ring-substituted derivatives interact with plasma membrane monoamine transporters and α
    Halberstadt AL; Brandt SD; Walther D; Baumann MH
    Psychopharmacology (Berl); 2019 Mar; 236(3):989-999. PubMed ID: 30904940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
    Dutta AK; Fei XS; Beardsley PM; Newman JL; Reith ME
    J Med Chem; 2001 Mar; 44(6):937-48. PubMed ID: 11300876
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monoamine transporter contributions to l-DOPA effects in hemi-parkinsonian rats.
    Conti MM; Meadows SM; Melikhov-Sosin M; Lindenbach D; Hallmark J; Werner DF; Bishop C
    Neuropharmacology; 2016 Nov; 110(Pt A):125-134. PubMed ID: 27452719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents.
    Dutta AK; Gopishetty B; Gogoi S; Ali S; Zhen J; Reith M
    Eur J Pharmacol; 2011 Dec; 671(1-3):39-44. PubMed ID: 21963455
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.