249 related articles for article (PubMed ID: 33844653)
1. Structure-based phylogeny identifies avoralstat as a TMPRSS2 inhibitor that prevents SARS-CoV-2 infection in mice.
Sun YJ; Velez G; Parsons DE; Li K; Ortiz ME; Sharma S; McCray PB; Bassuk AG; Mahajan VB
J Clin Invest; 2021 May; 131(10):. PubMed ID: 33844653
[TBL] [Abstract][Full Text] [Related]
2. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19.
Li K; Meyerholz DK; Bartlett JA; McCray PB
mBio; 2021 Aug; 12(4):e0097021. PubMed ID: 34340553
[TBL] [Abstract][Full Text] [Related]
3. Structural Basis of Covalent Inhibitory Mechanism of TMPRSS2-Related Serine Proteases by Camostat.
Sun G; Sui Y; Zhou Y; Ya J; Yuan C; Jiang L; Huang M
J Virol; 2021 Sep; 95(19):e0086121. PubMed ID: 34160253
[TBL] [Abstract][Full Text] [Related]
4. Efficacy of host cell serine protease inhibitor MM3122 against SARS-CoV-2 for treatment and prevention of COVID-19.
Boon ACM; Bricker TL; Fritch EJ; Leist SR; Gully K; Baric RS; Graham RL; Troan BV; Mahoney M; Janetka JW
J Virol; 2024 May; 98(5):e0190323. PubMed ID: 38593045
[TBL] [Abstract][Full Text] [Related]
5. Topical TMPRSS2 inhibition prevents SARS-CoV-2 infection in differentiated human airway cultures.
Guo W; Porter LM; Crozier TW; Coates M; Jha A; McKie M; Nathan JA; Lehner PJ; Greenwood EJ; McCaughan F
Life Sci Alliance; 2022 Apr; 5(4):. PubMed ID: 35110354
[TBL] [Abstract][Full Text] [Related]
6. Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M; Hofmann-Winkler H; Smith JC; Krüger N; Arora P; Sørensen LK; Søgaard OS; Hasselstrøm JB; Winkler M; Hempel T; Raich L; Olsson S; Danov O; Jonigk D; Yamazoe T; Yamatsuta K; Mizuno H; Ludwig S; Noé F; Kjolby M; Braun A; Sheltzer JM; Pöhlmann S
EBioMedicine; 2021 Mar; 65():103255. PubMed ID: 33676899
[TBL] [Abstract][Full Text] [Related]
7. Targeting the intestinal TMPRSS2 protease to prevent SARS-CoV-2 entry into enterocytes-prospects and challenges.
Mahmoud IS; Jarrar YB
Mol Biol Rep; 2021 May; 48(5):4667-4675. PubMed ID: 34023987
[TBL] [Abstract][Full Text] [Related]
8. Synergistic Block of SARS-CoV-2 Infection by Combined Drug Inhibition of the Host Entry Factors PIKfyve Kinase and TMPRSS2 Protease.
Kreutzberger AJB; Sanyal A; Ojha R; Pyle JD; Vapalahti O; Balistreri G; Kirchhausen T
J Virol; 2021 Oct; 95(21):e0097521. PubMed ID: 34406858
[TBL] [Abstract][Full Text] [Related]
9. Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells.
Kumar V; Dhanjal JK; Bhargava P; Kaul A; Wang J; Zhang H; Kaul SC; Wadhwa R; Sundar D
J Biomol Struct Dyn; 2022 Jan; 40(1):1-13. PubMed ID: 32469279
[TBL] [Abstract][Full Text] [Related]
10. The Transmembrane Protease TMPRSS2 as a Therapeutic Target for COVID-19 Treatment.
Wettstein L; Kirchhoff F; Münch J
Int J Mol Sci; 2022 Jan; 23(3):. PubMed ID: 35163273
[TBL] [Abstract][Full Text] [Related]
11. TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells.
Koch J; Uckeley ZM; Doldan P; Stanifer M; Boulant S; Lozach PY
EMBO J; 2021 Aug; 40(16):e107821. PubMed ID: 34159616
[TBL] [Abstract][Full Text] [Related]
12. Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection.
Padmanabhan P; Desikan R; Dixit NM
PLoS Comput Biol; 2020 Dec; 16(12):e1008461. PubMed ID: 33290397
[TBL] [Abstract][Full Text] [Related]
13. Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion.
Kaur U; Chakrabarti SS; Ojha B; Pathak BK; Singh A; Saso L; Chakrabarti S
Curr Drug Targets; 2021; 22(2):192-201. PubMed ID: 32972339
[TBL] [Abstract][Full Text] [Related]
14. The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner.
Yamamoto M; Kiso M; Sakai-Tagawa Y; Iwatsuki-Horimoto K; Imai M; Takeda M; Kinoshita N; Ohmagari N; Gohda J; Semba K; Matsuda Z; Kawaguchi Y; Kawaoka Y; Inoue JI
Viruses; 2020 Jun; 12(6):. PubMed ID: 32532094
[TBL] [Abstract][Full Text] [Related]
15. TMPRSS2 and furin are both essential for proteolytic activation of SARS-CoV-2 in human airway cells.
Bestle D; Heindl MR; Limburg H; Van Lam van T; Pilgram O; Moulton H; Stein DA; Hardes K; Eickmann M; Dolnik O; Rohde C; Klenk HD; Garten W; Steinmetzer T; Böttcher-Friebertshäuser E
Life Sci Alliance; 2020 Sep; 3(9):. PubMed ID: 32703818
[TBL] [Abstract][Full Text] [Related]
16. TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.
Qu B; Miskey C; Gömer A; Kleinert RDV; Ibanez SC; Eberle R; Ebenig A; Postmus D; Nocke MK; Herrmann M; Itotia TK; Herrmann ST; Heinen N; Höck S; Hastert FD; von Rhein C; Schürmann C; Li X; van Zandbergen G; Widera M; Ciesek S; Schnierle BS; Tarr AW; Steinmann E; Goffinet C; Pfaender S; Locker JK; Mühlebach MD; Todt D; Brown RJP
Proc Natl Acad Sci U S A; 2024 Jun; 121(23):e2407437121. PubMed ID: 38814864
[TBL] [Abstract][Full Text] [Related]
17. BC-11 is a covalent TMPRSS2 fragment inhibitor that impedes SARS-CoV-2 host cell entry.
Moumbock AFA; Tran HTT; Lamy E; Günther S
Arch Pharm (Weinheim); 2023 Jan; 356(1):e2200371. PubMed ID: 36316225
[TBL] [Abstract][Full Text] [Related]
18. Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.
Senapati S; Banerjee P; Bhagavatula S; Kushwaha PP; Kumar S
J Genet; 2021; 100(1):. PubMed ID: 33707363
[TBL] [Abstract][Full Text] [Related]
19. Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Wettstein L; Weil T; Conzelmann C; Müller JA; Groß R; Hirschenberger M; Seidel A; Klute S; Zech F; Prelli Bozzo C; Preising N; Fois G; Lochbaum R; Knaff PM; Mailänder V; Ständker L; Thal DR; Schumann C; Stenger S; Kleger A; Lochnit G; Mayer B; Ruiz-Blanco YB; Hoffmann M; Sparrer KMJ; Pöhlmann S; Sanchez-Garcia E; Kirchhoff F; Frick M; Münch J
Nat Commun; 2021 Mar; 12(1):1726. PubMed ID: 33741941
[TBL] [Abstract][Full Text] [Related]
20. A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry.
Chen Y; Lear TB; Evankovich JW; Larsen MB; Lin B; Alfaras I; Kennerdell JR; Salminen L; Camarco DP; Lockwood KC; Tuncer F; Liu J; Myerburg MM; McDyer JF; Liu Y; Finkel T; Chen BB
Nat Commun; 2021 Jun; 12(1):3907. PubMed ID: 34162861
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]