These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway. Rigby MJ; Ding Y; Farrugia MA; Feig M; Cortese GP; Mitchell H; Burger C; Puglielli L J Neurochem; 2020 Aug; 154(4):404-423. PubMed ID: 31945187 [TBL] [Abstract][Full Text] [Related]
3. Nε-lysine acetylation in the endoplasmic reticulum - a novel cellular mechanism that regulates proteostasis and autophagy. Farrugia MA; Puglielli L J Cell Sci; 2018 Nov; 131(22):. PubMed ID: 30446507 [TBL] [Abstract][Full Text] [Related]
4. Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Peng Y; Kim MJ; Hullinger R; O'Riordan KJ; Burger C; Pehar M; Puglielli L Brain; 2016 Mar; 139(Pt 3):937-52. PubMed ID: 26787453 [TBL] [Abstract][Full Text] [Related]
5. Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype. Peng Y; Shapiro SL; Banduseela VC; Dieterich IA; Hewitt KJ; Bresnick EH; Kong G; Zhang J; Schueler KL; Keller MP; Attie AD; Hacker TA; Sullivan R; Kielar-Grevstad E; Arriola Apelo SI; Lamming DW; Anderson RM; Puglielli L Aging Cell; 2018 Oct; 17(5):e12820. PubMed ID: 30051577 [TBL] [Abstract][Full Text] [Related]
6. Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway. Dieterich IA; Cui Y; Braun MM; Lawton AJ; Robinson NH; Peotter JL; Yu Q; Casler JC; Glick BS; Audhya A; Denu JM; Li L; Puglielli L Sci Rep; 2021 Jan; 11(1):2013. PubMed ID: 33479349 [TBL] [Abstract][Full Text] [Related]
7. ATase inhibition rescues age-associated proteotoxicity of the secretory pathway. Murie M; Peng Y; Rigby MJ; Dieterich IA; Farrugia MA; Endresen A; Bhattacharyya A; Puglielli L Commun Biol; 2022 Feb; 5(1):173. PubMed ID: 35217767 [TBL] [Abstract][Full Text] [Related]
9. AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability. Jonas MC; Pehar M; Puglielli L J Cell Sci; 2010 Oct; 123(Pt 19):3378-88. PubMed ID: 20826464 [TBL] [Abstract][Full Text] [Related]
10. The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides. Ding Y; Dellisanti CD; Ko MH; Czajkowski C; Puglielli L J Biol Chem; 2014 Nov; 289(46):32044-32055. PubMed ID: 25301944 [TBL] [Abstract][Full Text] [Related]
11. Post-translational regulation of CD133 by ATase1/ATase2-mediated lysine acetylation. Mak AB; Pehar M; Nixon AM; Williams RA; Uetrecht AC; Puglielli L; Moffat J J Mol Biol; 2014 May; 426(11):2175-82. PubMed ID: 24556617 [TBL] [Abstract][Full Text] [Related]
12. Nϵ-lysine acetylation in the lumen of the endoplasmic reticulum: A way to regulate autophagy and maintain protein homeostasis in the secretory pathway. Peng Y; Puglielli L Autophagy; 2016 Jun; 12(6):1051-2. PubMed ID: 27124586 [TBL] [Abstract][Full Text] [Related]
13. Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation. Ding Y; Ko MH; Pehar M; Kotch F; Peters NR; Luo Y; Salamat SM; Puglielli L J Biol Chem; 2012 Mar; 287(11):8424-33. PubMed ID: 22267734 [TBL] [Abstract][Full Text] [Related]
14. N-acetylation of secreted proteins in Apicomplexa is widespread and is independent of the ER acetyl-CoA transporter AT1. Nyonda MA; Boyer JB; Belmudes L; Krishnan A; Pino P; Couté Y; Brochet M; Meinnel T; Soldati-Favre D; Giglione C J Cell Sci; 2022 Aug; 135(15):. PubMed ID: 35621049 [TBL] [Abstract][Full Text] [Related]
15. Intracellular Citrate/acetyl-CoA flux and endoplasmic reticulum acetylation: Connectivity is the answer. Fernandez-Fuente G; Rigby MJ; Puglielli L Mol Metab; 2023 Jan; 67():101653. PubMed ID: 36513219 [TBL] [Abstract][Full Text] [Related]
16. PanM, an acetyl-coenzyme A sensor required for maturation of L-aspartate decarboxylase (PanD). Stuecker TN; Tucker AC; Escalante-Semerena JC mBio; 2012; 3(4):. PubMed ID: 22782525 [TBL] [Abstract][Full Text] [Related]
17. ATL3, a cargo receptor for reticulophagy. Chen Q; Teng J; Chen J Autophagy; 2019 Aug; 15(8):1465-1466. PubMed ID: 31032711 [TBL] [Abstract][Full Text] [Related]
18. Developmentally regulated selective autophagy determines ER inheritance by gametes. Otto GM; Brar GA Autophagy; 2022 Jul; 18(7):1732-1733. PubMed ID: 35220897 [TBL] [Abstract][Full Text] [Related]
19. Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer. Peng Y; Li M; Clarkson BD; Pehar M; Lao PJ; Hillmer AT; Barnhart TE; Christian BT; Mitchell HA; Bendlin BB; Sandor M; Puglielli L J Neurosci; 2014 May; 34(20):6772-89. PubMed ID: 24828632 [TBL] [Abstract][Full Text] [Related]
20. Spatial selectivity of ATase inhibition in mouse models of Charcot-Marie-Tooth disease. Fernandez-Fuente G; Farrugia MA; Peng Y; Schneider A; Svaren J; Puglielli L Brain Commun; 2024; 6(4):fcae232. PubMed ID: 39035418 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]