BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

306 related articles for article (PubMed ID: 33852844)

  • 1. Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
    Migazzi A; Scaramuzzino C; Anderson EN; Tripathy D; Hernández IH; Grant RA; Roccuzzo M; Tosatto L; Virlogeux A; Zuccato C; Caricasole A; Ratovitski T; Ross CA; Pandey UB; Lucas JJ; Saudou F; Pennuto M; Basso M
    Cell Rep; 2021 Apr; 35(2):108980. PubMed ID: 33852844
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of huntingtin with PRMTs and its subsequent arginine methylation affects HTT solubility, phase transition behavior and neuronal toxicity.
    Ratovitski T; Jiang M; O'Meally RN; Rauniyar P; Chighladze E; Faragó A; Kamath SV; Jin J; Shevelkin AV; Cole RN; Ross CA
    Hum Mol Genet; 2022 May; 31(10):1651-1672. PubMed ID: 34888656
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
    Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
    Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease.
    White JA; Krzystek TJ; Hoffmar-Glennon H; Thant C; Zimmerman K; Iacobucci G; Vail J; Thurston L; Rahman S; Gunawardena S
    Acta Neuropathol Commun; 2020 Jul; 8(1):97. PubMed ID: 32611447
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
    Wong YC; Holzbaur EL
    J Neurosci; 2014 Jan; 34(4):1293-305. PubMed ID: 24453320
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.
    Zala D; Colin E; Rangone H; Liot G; Humbert S; Saudou F
    Hum Mol Genet; 2008 Dec; 17(24):3837-46. PubMed ID: 18772195
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant Huntingtin alters retrograde transport of TrkB receptors in striatal dendrites.
    Liot G; Zala D; Pla P; Mottet G; Piel M; Saudou F
    J Neurosci; 2013 Apr; 33(15):6298-309. PubMed ID: 23575829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons.
    Sinadinos C; Burbidge-King T; Soh D; Thompson LM; Marsh JL; Wyttenbach A; Mudher AK
    Neurobiol Dis; 2009 May; 34(2):389-95. PubMed ID: 19268537
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.
    Trushina E; Dyer RB; Badger JD; Ure D; Eide L; Tran DD; Vrieze BT; Legendre-Guillemin V; McPherson PS; Mandavilli BS; Van Houten B; Zeitlin S; McNiven M; Aebersold R; Hayden M; Parisi JE; Seeberg E; Dragatsis I; Doyle K; Bender A; Chacko C; McMurray CT
    Mol Cell Biol; 2004 Sep; 24(18):8195-209. PubMed ID: 15340079
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
    Shirendeb UP; Calkins MJ; Manczak M; Anekonda V; Dufour B; McBride JL; Mao P; Reddy PH
    Hum Mol Genet; 2012 Jan; 21(2):406-20. PubMed ID: 21997870
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
    Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
    Elife; 2021 Apr; 10():. PubMed ID: 33871358
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of Twist1 in mutant huntingtin-induced transcriptional alterations and neurotoxicity.
    Pan Y; Zhu Y; Yang W; Tycksen E; Liu S; Palucki J; Zhu L; Sasaki Y; Sharma MK; Kim AH; Zhang B; Yano H
    J Biol Chem; 2018 Jul; 293(30):11850-11866. PubMed ID: 29891550
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Huntingtin's function in axonal transport is conserved in Drosophila melanogaster.
    Zala D; Hinckelmann MV; Saudou F
    PLoS One; 2013; 8(3):e60162. PubMed ID: 23555909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease.
    Reddy PH; Shirendeb UP
    Biochim Biophys Acta; 2012 Feb; 1822(2):101-10. PubMed ID: 22080977
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity.
    Krench M; Littleton JT
    Fly (Austin); 2013; 7(4):229-36. PubMed ID: 24022020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rab8 Promotes Mutant HTT Aggregation, Reduces Neurodegeneration, and Ameliorates Behavioural Alterations in a Drosophila Model of Huntington's Disease.
    Delfino L; Mason RP; Kyriacou CP; Giorgini F; Rosato E
    J Huntingtons Dis; 2020; 9(3):253-263. PubMed ID: 33044189
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
    Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.
    Graham RK; Deng Y; Carroll J; Vaid K; Cowan C; Pouladi MA; Metzler M; Bissada N; Wang L; Faull RL; Gray M; Yang XW; Raymond LA; Hayden MR
    J Neurosci; 2010 Nov; 30(45):15019-29. PubMed ID: 21068307
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice.
    Apostol BL; Simmons DA; Zuccato C; Illes K; Pallos J; Casale M; Conforti P; Ramos C; Roarke M; Kathuria S; Cattaneo E; Marsh JL; Thompson LM
    Mol Cell Neurosci; 2008 Sep; 39(1):8-20. PubMed ID: 18602275
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.