These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
281 related articles for article (PubMed ID: 33859386)
1. Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning. Mason DM; Friedensohn S; Weber CR; Jordi C; Wagner B; Meng SM; Ehling RA; Bonati L; Dahinden J; Gainza P; Correia BE; Reddy ST Nat Biomed Eng; 2021 Jun; 5(6):600-612. PubMed ID: 33859386 [TBL] [Abstract][Full Text] [Related]
2. High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis. Mason DM; Weber CR; Parola C; Meng SM; Greiff V; Kelton WJ; Reddy ST Nucleic Acids Res; 2018 Aug; 46(14):7436-7449. PubMed ID: 29931269 [TBL] [Abstract][Full Text] [Related]
3. Conformational changes in a Vernier zone region: Implications for antibody dual specificity. Arslan M; Karadag D; Kalyoncu S Proteins; 2020 Nov; 88(11):1447-1457. PubMed ID: 32526069 [TBL] [Abstract][Full Text] [Related]
4. Biochemistry, structure, and cellular internalization of a four nanobody-bearing Fc dimer. Chabrol E; Fagnen C; Landron S; Marcheteau E; Stojko J; Guenin SP; Antoine M; Fould B; Ferry G; Boutin JA; Vénien-Bryan C Protein Sci; 2021 Sep; 30(9):1946-1957. PubMed ID: 34117809 [TBL] [Abstract][Full Text] [Related]
5. High affinity antigen recognition of the dual specific variants of herceptin is entropy-driven in spite of structural plasticity. Bostrom J; Haber L; Koenig P; Kelley RF; Fuh G PLoS One; 2011 Apr; 6(4):e17887. PubMed ID: 21526167 [TBL] [Abstract][Full Text] [Related]
6. AttABseq: an attention-based deep learning prediction method for antigen-antibody binding affinity changes based on protein sequences. Jin R; Ye Q; Wang J; Cao Z; Jiang D; Wang T; Kang Y; Xu W; Hsieh CY; Hou T Brief Bioinform; 2024 May; 25(4):. PubMed ID: 38960407 [TBL] [Abstract][Full Text] [Related]
7. Application of proteometric approach for identification of functional mutant sites to improve the binding affinity of anticancer biologic trastuzumab with its antigen human epidermal growth factor receptor 2. Balakrishnan N; Gurunathan B; Surapaneni KM J Mol Recognit; 2020 Feb; 33(2):e2818. PubMed ID: 31693267 [TBL] [Abstract][Full Text] [Related]
8. Identification of critical chemical modifications by size exclusion chromatography of stressed antibody-target complexes with competitive binding. Shi RL; Xiao G; Dillon TM; McAuley A; Ricci MS; Bondarenko PV MAbs; 2021; 13(1):1887612. PubMed ID: 33616001 [TBL] [Abstract][Full Text] [Related]
9. Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment. Sulea T; Rohani N; Baardsnes J; Corbeil CR; Deprez C; Cepero-Donates Y; Robert A; Schrag JD; Parat M; Duchesne M; Jaramillo ML; Purisima EO; Zwaagstra JC MAbs; 2020; 12(1):1682866. PubMed ID: 31777319 [TBL] [Abstract][Full Text] [Related]
10. The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding. Su CT; Ling WL; Lua WH; Poh JJ; Gan SK Sci Rep; 2017 Jun; 7(1):3766. PubMed ID: 28630463 [TBL] [Abstract][Full Text] [Related]
11. Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates. Zwaagstra JC; Sulea T; Baardsnes J; Radinovic S; Cepero-Donates Y; Robert A; O'Connor-McCourt MD; Tikhomirov IA; Jaramillo ML PLoS One; 2019; 14(12):e0226593. PubMed ID: 31891584 [TBL] [Abstract][Full Text] [Related]
12. Monoclonal antibody therapeutics with up to five specificities: functional enhancement through fusion of target-specific peptides. LaFleur DW; Abramyan D; Kanakaraj P; Smith RG; Shah RR; Wang G; Yao XT; Kankanala S; Boyd E; Zaritskaya L; Nam V; Puffer BA; Buasen P; Kaithamana S; Burnette AF; Krishnamurthy R; Patel D; Roschke VV; Kiener PA; Hilbert DM; Barbas CF MAbs; 2013; 5(2):208-18. PubMed ID: 23575268 [TBL] [Abstract][Full Text] [Related]
13. Generation and testing of engineered multimeric Fabs of trastuzumab. Selis F; Sandomenico A; Cantile M; Sanna R; Calvanese L; Falcigno L; Dell'Omo P; Esperti A; De Falco S; Focà A; Caporale A; Iaccarino E; Truppo E; Scaramuzza S; Tonon G; Ruvo M Int J Biol Macromol; 2020 Dec; 164():4516-4531. PubMed ID: 32941911 [TBL] [Abstract][Full Text] [Related]
14. Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities. Jian JW; Chen HS; Chiu YK; Peng HP; Tung CP; Chen IC; Yu CM; Tsou YL; Kuo WY; Hsu HJ; Yang AS MAbs; 2019; 11(2):373-387. PubMed ID: 30526270 [TBL] [Abstract][Full Text] [Related]
15. Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site. Bostrom J; Yu SF; Kan D; Appleton BA; Lee CV; Billeci K; Man W; Peale F; Ross S; Wiesmann C; Fuh G Science; 2009 Mar; 323(5921):1610-4. PubMed ID: 19299620 [TBL] [Abstract][Full Text] [Related]
16. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues. Wu H; Nie Y; Huse WD; Watkins JD J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035 [TBL] [Abstract][Full Text] [Related]
17. Redirecting adenoviruses to tumour cells using therapeutic antibodies: Generation of a versatile human bispecific adaptor. Vasiljevic S; Beale EV; Bonomelli C; Easthope IS; Pritchard LK; Seabright GE; Caputo AT; Scanlan CN; Dalziel M; Crispin M Mol Immunol; 2015 Dec; 68(2 Pt A):234-43. PubMed ID: 26391350 [TBL] [Abstract][Full Text] [Related]
18. Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody. Gerstner RB; Carter P; Lowman HB J Mol Biol; 2002 Aug; 321(5):851-62. PubMed ID: 12206766 [TBL] [Abstract][Full Text] [Related]
19. Assessment of flexible backbone protein design methods for sequence library prediction in the therapeutic antibody Herceptin-HER2 interface. Babor M; Mandell DJ; Kortemme T Protein Sci; 2011 Jun; 20(6):1082-9. PubMed ID: 21465611 [TBL] [Abstract][Full Text] [Related]
20. Effect of VH-VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding. Ling WL; Lua WH; Poh JJ; Yeo JY; Lane DP; Gan SK Front Immunol; 2018; 9():469. PubMed ID: 29593727 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]