183 related articles for article (PubMed ID: 33859800)
1. Discovery of the First Orally Available, Selective K
Griffin AM; Kahlig KM; Hatch RJ; Hughes ZA; Chapman ML; Antonio B; Marron BE; Wittmann M; Martinez-Botella G
ACS Med Chem Lett; 2021 Apr; 12(4):593-602. PubMed ID: 33859800
[TBL] [Abstract][Full Text] [Related]
2. Small-molecule inhibitors of Slack potassium channels as potential therapeutics for childhood epilepsies.
M Qunies A; A Emmitte K
Pharm Pat Anal; 2022 Mar; 11(2):45-56. PubMed ID: 35369761
[TBL] [Abstract][Full Text] [Related]
3. K
Gertler TS; Cherian S; DeKeyser JM; Kearney JA; George AL
Neurobiol Dis; 2022 Jun; 168():105713. PubMed ID: 35346832
[TBL] [Abstract][Full Text] [Related]
4. Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (K
Quraishi IH; Mercier MR; McClure H; Couture RL; Schwartz ML; Lukowski R; Ruth P; Kaczmarek LK
Sci Rep; 2020 Feb; 10(1):3213. PubMed ID: 32081855
[TBL] [Abstract][Full Text] [Related]
5. The Epilepsy of Infancy With Migrating Focal Seizures: Identification of
Mao X; Bruneau N; Gao Q; Becq H; Jia Z; Xi H; Shu L; Wang H; Szepetowski P; Aniksztejn L
Front Cell Neurosci; 2020; 14():1. PubMed ID: 32038177
[TBL] [Abstract][Full Text] [Related]
6. In silico model reveals the key role of GABA in KCNT1-epilepsy in infancy with migrating focal seizures.
Kuchenbuch M; Nabbout R; Yochum M; Sauleau P; Modolo J; Wendling F; Benquet P
Epilepsia; 2021 Mar; 62(3):683-697. PubMed ID: 33617692
[TBL] [Abstract][Full Text] [Related]
7. Targeting K
Cole BA; Clapcote SJ; Muench SP; Lippiat JD
Trends Pharmacol Sci; 2021 Aug; 42(8):700-713. PubMed ID: 34074526
[TBL] [Abstract][Full Text] [Related]
8. The Phe932Ile mutation in KCNT1 channels associated with severe epilepsy, delayed myelination and leukoencephalopathy produces a loss-of-function channel phenotype.
Evely KM; Pryce KD; Bhattacharjee A
Neuroscience; 2017 May; 351():65-70. PubMed ID: 28366665
[TBL] [Abstract][Full Text] [Related]
9. Structure-Activity Relationship Studies in a Series of Xanthine Inhibitors of SLACK Potassium Channels.
Qunies AM; Spitznagel BD; Du Y; Peprah PK; Mohamed YK; Weaver CD; Emmitte KA
Molecules; 2024 May; 29(11):. PubMed ID: 38893312
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685.
Qunies AM; Spitznagel BD; Du Y; David Weaver C; Emmitte KA
Bioorg Med Chem; 2023 Nov; 95():117487. PubMed ID: 37812884
[TBL] [Abstract][Full Text] [Related]
11. Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons.
Wu J; Quraishi IH; Zhang Y; Bromwich M; Kaczmarek LK
Cell Rep; 2024 Mar; 43(3):113904. PubMed ID: 38457342
[TBL] [Abstract][Full Text] [Related]
12. Two Patients With KCNT1-Related Epilepsy Responding to Phenobarbital and Potassium Bromide.
Datta AN; Michoulas A; Guella I; ; Demos M
J Child Neurol; 2019 Oct; 34(12):728-734. PubMed ID: 31208268
[No Abstract] [Full Text] [Related]
13. Clinical and molecular characterization of
McTague A; Nair U; Malhotra S; Meyer E; Trump N; Gazina EV; Papandreou A; Ngoh A; Ackermann S; Ambegaonkar G; Appleton R; Desurkar A; Eltze C; Kneen R; Kumar AV; Lascelles K; Montgomery T; Ramesh V; Samanta R; Scott RH; Tan J; Whitehouse W; Poduri A; Scheffer IE; Chong WKK; Cross JH; Topf M; Petrou S; Kurian MA
Neurology; 2018 Jan; 90(1):e55-e66. PubMed ID: 29196579
[TBL] [Abstract][Full Text] [Related]
14. Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy.
Dilena R; DiFrancesco JC; Soldovieri MV; Giacobbe A; Ambrosino P; Mosca I; Galli MA; Guez S; Fumagalli M; Miceli F; Cattaneo D; Darra F; Gennaro E; Zara F; Striano P; Castellotti B; Gellera C; Varesio C; Veggiotti P; Taglialatela M
Neurotherapeutics; 2018 Oct; 15(4):1112-1126. PubMed ID: 30112700
[TBL] [Abstract][Full Text] [Related]
15. New use for an old drug: quinidine in KCNT1-related epilepsy therapy.
Liu R; Sun L; Wang Y; Wang Q; Wu J
Neurol Sci; 2023 Apr; 44(4):1201-1206. PubMed ID: 36437393
[TBL] [Abstract][Full Text] [Related]
16. Antisense oligonucleotide therapy for KCNT1 encephalopathy.
Burbano LE; Li M; Jancovski N; Jafar-Nejad P; Richards K; Sedo A; Soriano A; Rollo B; Jia L; Gazina EV; Piltz S; Adikusuma F; Thomas PQ; Kopsidas H; Rigo F; Reid CA; Maljevic S; Petrou S
JCI Insight; 2022 Dec; 7(23):. PubMed ID: 36173683
[TBL] [Abstract][Full Text] [Related]
17. KCNT1 epilepsy with migrating focal seizures shows a temporal sequence with poor outcome, high mortality and SUDEP.
Kuchenbuch M; Barcia G; Chemaly N; Carme E; Roubertie A; Gibaud M; Van Bogaert P; de Saint Martin A; Hirsch E; Dubois F; Sarret C; Nguyen The Tich S; Laroche C; des Portes V; Billette de Villemeur T; Barthez MA; Auvin S; Bahi-Buisson N; Desguerre I; Kaminska A; Benquet P; Nabbout R
Brain; 2019 Oct; 142(10):2996-3008. PubMed ID: 31532509
[TBL] [Abstract][Full Text] [Related]
18. Mutations in KCNT1 cause a spectrum of focal epilepsies.
Møller RS; Heron SE; Larsen LH; Lim CX; Ricos MG; Bayly MA; van Kempen MJ; Klinkenberg S; Andrews I; Kelley K; Ronen GM; Callen D; McMahon JM; Yendle SC; Carvill GL; Mefford HC; Nabbout R; Poduri A; Striano P; Baglietto MG; Zara F; Smith NJ; Pridmore C; Gardella E; Nikanorova M; Dahl HA; Gellert P; Scheffer IE; Gunning B; Kragh-Olsen B; Dibbens LM
Epilepsia; 2015 Sep; 56(9):e114-20. PubMed ID: 26122718
[TBL] [Abstract][Full Text] [Related]
19. KCNT1 mutations in seizure disorders: the phenotypic spectrum and functional effects.
Lim CX; Ricos MG; Dibbens LM; Heron SE
J Med Genet; 2016 Apr; 53(4):217-25. PubMed ID: 26740507
[TBL] [Abstract][Full Text] [Related]
20. Disease-causing Slack potassium channel mutations produce opposite effects on excitability of excitatory and inhibitory neurons.
Wu J; Quraishi IH; Zhang Y; Bromwich M; Kaczmarek LK
bioRxiv; 2023 Feb; ():. PubMed ID: 36824888
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
