153 related articles for article (PubMed ID: 33860180)
1. Tropane-Based Ibogaine Analog Rescues Folding-Deficient Serotonin and Dopamine Transporters.
Bhat S; Guthrie DA; Kasture A; El-Kasaby A; Cao J; Bonifazi A; Ku T; Giancola JB; Hummel T; Freissmuth M; Newman AH
ACS Pharmacol Transl Sci; 2021 Apr; 4(2):503-516. PubMed ID: 33860180
[TBL] [Abstract][Full Text] [Related]
2. Pharmacochaperoning in a
Asjad HMM; Kasture A; El-Kasaby A; Sackel M; Hummel T; Freissmuth M; Sucic S
J Biol Chem; 2017 Nov; 292(47):19250-19265. PubMed ID: 28972153
[TBL] [Abstract][Full Text] [Related]
3. Functional Rescue of a Misfolded
Kasture A; El-Kasaby A; Szöllősi D; Asjad HMM; Grimm A; Stockner T; Hummel T; Freissmuth M; Sucic S
J Biol Chem; 2016 Sep; 291(40):20876-20890. PubMed ID: 27481941
[TBL] [Abstract][Full Text] [Related]
4. When transporters fail to be transported: how to rescue folding-deficient SLC6 transporters.
Sucic S; Kasture A; Mazhar Asjad HM; Kern C; El-Kasaby A; Freissmuth M
J Neurol Neuromedicine; 2016 Dec; 1(9):34-40. PubMed ID: 28405636
[TBL] [Abstract][Full Text] [Related]
5. SLC6 Transporter Folding Diseases and Pharmacochaperoning.
Freissmuth M; Stockner T; Sucic S
Handb Exp Pharmacol; 2018; 245():249-270. PubMed ID: 29086036
[TBL] [Abstract][Full Text] [Related]
6. Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.
Beerepoot P; Lam VM; Salahpour A
J Biol Chem; 2016 Oct; 291(42):22053-22062. PubMed ID: 27555326
[TBL] [Abstract][Full Text] [Related]
7. Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.
El-Kasaby A; Just H; Malle E; Stolt-Bergner PC; Sitte HH; Freissmuth M; Kudlacek O
J Biol Chem; 2010 Dec; 285(50):39201-10. PubMed ID: 20889976
[TBL] [Abstract][Full Text] [Related]
8. How to rescue misfolded SERT, DAT and NET: targeting conformational intermediates with atypical inhibitors and partial releasers.
Bhat S; Newman AH; Freissmuth M
Biochem Soc Trans; 2019 Jun; 47(3):861-874. PubMed ID: 31064865
[TBL] [Abstract][Full Text] [Related]
9. Rescue by 4-phenylbutyrate of several misfolded creatine transporter-1 variants linked to the creatine transporter deficiency syndrome.
El-Kasaby A; Kasture A; Koban F; Hotka M; Asjad HMM; Kubista H; Freissmuth M; Sucic S
Neuropharmacology; 2019 Dec; 161():107572. PubMed ID: 30885608
[TBL] [Abstract][Full Text] [Related]
10. Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters.
Asjad HMM; Nasrollahi-Shirazi S; Sucic S; Freissmuth M; Nanoff C
Int J Mol Sci; 2017 Nov; 18(11):. PubMed ID: 29135937
[TBL] [Abstract][Full Text] [Related]
11. Structure-Activity Relationships of Dopamine Transporter Pharmacological Chaperones.
Sutton C; Williams EQ; Homsi H; Beerepoot P; Nazari R; Han D; Ramsey AJ; Mash DC; Olson DE; Blough B; Salahpour A
Front Cell Neurosci; 2022; 16():832536. PubMed ID: 35614973
[TBL] [Abstract][Full Text] [Related]
12. Irreversible binding of a novel phenylisothiocyanate tropane analog to monoamine transporters in rat brain.
Murthy V; Davies HM; Hedley SJ; Childers SR
Biochem Pharmacol; 2007 Jul; 74(2):336-44. PubMed ID: 17540345
[TBL] [Abstract][Full Text] [Related]
13. In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats.
Baumann MH; Rothman RB; Pablo JP; Mash DC
J Pharmacol Exp Ther; 2001 May; 297(2):531-9. PubMed ID: 11303040
[TBL] [Abstract][Full Text] [Related]
14. Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.
Bhat S; Hasenhuetl PS; Kasture A; El-Kasaby A; Baumann MH; Blough BE; Sucic S; Sandtner W; Freissmuth M
J Biol Chem; 2017 Oct; 292(40):16773-16786. PubMed ID: 28842491
[TBL] [Abstract][Full Text] [Related]
15. Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits.
Bhat S; El-Kasaby A; Freissmuth M; Sucic S
Pharmacol Ther; 2021 Jun; 222():107785. PubMed ID: 33310157
[TBL] [Abstract][Full Text] [Related]
16. The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome.
Farr CV; El-Kasaby A; Freissmuth M; Sucic S
Front Synaptic Neurosci; 2020; 12():588954. PubMed ID: 33192443
[TBL] [Abstract][Full Text] [Related]
17. Quantitative autoradiography of ligands for dopamine receptors and transporters in brain of Göttingen minipig: comparison with results in vivo.
Minuzzi L; Olsen AK; Bender D; Arnfred S; Grant R; Danielsen EH; Cumming P
Synapse; 2006 Mar; 59(4):211-9. PubMed ID: 16385509
[TBL] [Abstract][Full Text] [Related]
18. Interrogating the Molecular Basis for Substrate Recognition in Serotonin and Dopamine Transporters with High-Affinity Substrate-Based Bivalent Ligands.
Andersen J; Ladefoged LK; Kristensen TN; Munro L; Grouleff J; Stuhr-Hansen N; Kristensen AS; Schiøtt B; Strømgaard K
ACS Chem Neurosci; 2016 Oct; 7(10):1406-1417. PubMed ID: 27425420
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
Zou MF; Cao J; Kopajtic T; Desai RI; Katz JL; Newman AH
J Med Chem; 2006 Oct; 49(21):6391-9. PubMed ID: 17034144
[TBL] [Abstract][Full Text] [Related]
20. Folding correction of ABC-transporter ABCB1 by pharmacological chaperones: a mechanistic concept.
Spork M; Sohail MI; Schmid D; Ecker GF; Freissmuth M; Chiba P; Stockner T
Pharmacol Res Perspect; 2017 Jun; 5(3):e00325. PubMed ID: 28603639
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]