These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
25. Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells. Peng Q; Alqahtani S; Nasrullah MZA; Shen J Eur J Pharmacol; 2021 Jan; 891():173706. PubMed ID: 33152337 [TBL] [Abstract][Full Text] [Related]
26. Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359. Crüsemann M; Reher R; Schamari I; Brachmann AO; Ohbayashi T; Kuschak M; Malfacini D; Seidinger A; Pinto-Carbó M; Richarz R; Reuter T; Kehraus S; Hallab A; Attwood M; Schiöth HB; Mergaert P; Kikuchi Y; Schäberle TF; Kostenis E; Wenzel D; Müller CE; Piel J; Carlier A; Eberl L; König GM Angew Chem Int Ed Engl; 2018 Jan; 57(3):836-840. PubMed ID: 29194875 [TBL] [Abstract][Full Text] [Related]
27. Applying Molecular Networking for the Detection of Natural Sources and Analogues of the Selective Gq Protein Inhibitor FR900359. Reher R; Kuschak M; Heycke N; Annala S; Kehraus S; Dai HF; Müller CE; Kostenis E; König GM; Crüsemann M J Nat Prod; 2018 Jul; 81(7):1628-1635. PubMed ID: 29943987 [TBL] [Abstract][Full Text] [Related]
28. The chromodepsins - chemistry, biology and biosynthesis of a selective Gq inhibitor natural product family. Hermes C; König GM; Crüsemann M Nat Prod Rep; 2021 Dec; 38(12):2276-2292. PubMed ID: 33998635 [TBL] [Abstract][Full Text] [Related]
30. Promoter-Driven Overexpression in Chromobacterium vaccinii Facilitates Access to FR900359 and Yields Novel Low Abundance Analogs. Pistorius D; Buntin K; Weber E; Richard E; Bouquet C; Wollbrett S; Regenass H; Peón V; Böhm M; Kessler R; Gempeler T; Haberkorn A; Wimmer L; Lanshoeft C; Davis J; Hainzl D; D'Alessio JA; Manchado E; Petersen F Chemistry; 2022 Feb; 28(8):e202103888. PubMed ID: 34878202 [TBL] [Abstract][Full Text] [Related]
31. Condensation domain editing of the FR900359 assembly line yields a novel analog amenable to late-stage functionalization. Pistorius D; Richard E; Buntin K; Dresen K; Wollbrett S; Weber E; Haberkorn A; Manchado E; Petersen F Chembiochem; 2024 Jul; ():e202400491. PubMed ID: 39076125 [TBL] [Abstract][Full Text] [Related]
32. Building Chemical Probes Based on the Natural Products YM-254890 and FR900359: Advances toward Scalability. Medcalf MR; Krueger RL; Medcalf ZT; Rosston PA; Zhu Y; Kaltenbronn KM; Blumer KJ; Moeller KD Synthesis (Stuttg); 2023 Jan; 55(1):90-106. PubMed ID: 36644007 [TBL] [Abstract][Full Text] [Related]
33. The Bacterial G Hanke W; Alenfelder J; Liu J; Gutbrod P; Kehraus S; Crüsemann M; Dörmann P; Kostenis E; Scholz M; König GM J Chem Ecol; 2023 Oct; 49(9-10):549-569. PubMed ID: 37453001 [TBL] [Abstract][Full Text] [Related]
34. Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule. Nishimura A; Kitano K; Takasaki J; Taniguchi M; Mizuno N; Tago K; Hakoshima T; Itoh H Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13666-71. PubMed ID: 20639466 [TBL] [Abstract][Full Text] [Related]
35. Structural response of G protein binding to the cyclodepsipeptide inhibitor FR900359 probed by NMR spectroscopy. Bonifer C; Hanke W; Mühle J; Löhr F; Becker-Baldus J; Nagel J; Schertler GFX; Müller CE; König GM; Hilger D; Glaubitz C Chem Sci; 2024 Aug; 15(32):12939-12956. PubMed ID: 39148790 [TBL] [Abstract][Full Text] [Related]
36. A Building Block Approach for the Total Synthesis of YM-385781. Zhu Y; Liu S; Zigmond J; Kaltenbronn KM; Blumer KJ; Moeller KD European J Org Chem; 2023 May; 26(20):. PubMed ID: 38188369 [TBL] [Abstract][Full Text] [Related]
37. Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice. Kawasaki T; Taniguchi M; Moritani Y; Uemura T; Shigenaga T; Takamatsu H; Hayashi K; Takasaki J; Saito T; Nagai K Thromb Haemost; 2005 Jul; 94(1):184-92. PubMed ID: 16113802 [TBL] [Abstract][Full Text] [Related]
39. Examination of signalling pathways involved in muscarinic responses in bovine ciliary muscle using YM-254890, an inhibitor of the Gq/11 protein. Yasui F; Miyazu M; Yoshida A; Naruse K; Takai A Br J Pharmacol; 2008 Jun; 154(4):890-900. PubMed ID: 18536740 [TBL] [Abstract][Full Text] [Related]