BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 33860275)

  • 1. TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia.
    Yun S; Vincelette ND; Yu X; Watson GW; Fernandez MR; Yang C; Hitosugi T; Cheng CH; Freischel AR; Zhang L; Li W; Hou H; Schaub FX; Vedder AR; Cen L; McGraw KL; Moon J; Murphy DJ; Ballabio A; Kaufmann SH; Berglund AE; Cleveland JL
    Blood Cancer Discov; 2021 Mar; 2(2):162-185. PubMed ID: 33860275
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy.
    Fernandez MR; Schaub FX; Yang C; Li W; Yun S; Schaub SK; Dorsey FC; Liu M; Steeves MA; Ballabio A; Tzankov A; Chen Z; Koomen JM; Berglund AE; Cleveland JL
    Cancer Res; 2022 Apr; 82(7):1234-1250. PubMed ID: 35149590
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
    Figueroa ME; Abdel-Wahab O; Lu C; Ward PS; Patel J; Shih A; Li Y; Bhagwat N; Vasanthakumar A; Fernandez HF; Tallman MS; Sun Z; Wolniak K; Peeters JK; Liu W; Choe SE; Fantin VR; Paietta E; Löwenberg B; Licht JD; Godley LA; Delwel R; Valk PJ; Thompson CB; Levine RL; Melnick A
    Cancer Cell; 2010 Dec; 18(6):553-67. PubMed ID: 21130701
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reductive TCA cycle catalyzed by wild-type IDH2 promotes acute myeloid leukemia and is a metabolic vulnerability for potential targeted therapy.
    Zeng P; Lu W; Tian J; Qiao S; Li J; Glorieux C; Wen S; Zhang H; Li Y; Huang P
    J Hematol Oncol; 2022 Mar; 15(1):30. PubMed ID: 35313945
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication.
    Paschka P; Schlenk RF; Gaidzik VI; Habdank M; Krönke J; Bullinger L; Späth D; Kayser S; Zucknick M; Götze K; Horst HA; Germing U; Döhner H; Döhner K
    J Clin Oncol; 2010 Aug; 28(22):3636-43. PubMed ID: 20567020
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of mutant IDH1 and IDH2 inhibitors in the treatment of acute myeloid leukemia.
    Nassereddine S; Lap CJ; Haroun F; Tabbara I
    Ann Hematol; 2017 Dec; 96(12):1983-1991. PubMed ID: 29090344
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in
    Shih AH; Meydan C; Shank K; Garrett-Bakelman FE; Ward PS; Intlekofer AM; Nazir A; Stein EM; Knapp K; Glass J; Travins J; Straley K; Gliser C; Mason CE; Yen K; Thompson CB; Melnick A; Levine RL
    Cancer Discov; 2017 May; 7(5):494-505. PubMed ID: 28193779
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients.
    Atef M; Shafik NF; H A Hassan N; Allam RM; El-Meligui YM; Abdelaziz H
    Asian Pac J Cancer Prev; 2023 Sep; 24(9):3169-3182. PubMed ID: 37774069
    [TBL] [Abstract][Full Text] [Related]  

  • 9. All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL).
    Orfali N; O'Donovan TR; Cahill MR; Benjamin D; Nanus DM; McKenna SL; Gudas LJ; Mongan NP
    Eur J Haematol; 2020 Mar; 104(3):236-250. PubMed ID: 31811682
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors.
    Call SG; Duren RP; Panigrahi AK; Nguyen L; Freire PR; Grimm SL; Coarfa C; Conneely OM
    Sci Rep; 2020 Feb; 10(1):2851. PubMed ID: 32071334
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
    Chotirat S; Thongnoppakhun W; Promsuwicha O; Boonthimat C; Auewarakul CU
    J Hematol Oncol; 2012 Mar; 5():5. PubMed ID: 22397365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.
    Boutzen H; Saland E; Larrue C; de Toni F; Gales L; Castelli FA; Cathebas M; Zaghdoudi S; Stuani L; Kaoma T; Riscal R; Yang G; Hirsch P; David M; De Mas-Mansat V; Delabesse E; Vallar L; Delhommeau F; Jouanin I; Ouerfelli O; Le Cam L; Linares LK; Junot C; Portais JC; Vergez F; Récher C; Sarry JE
    J Exp Med; 2016 Apr; 213(4):483-97. PubMed ID: 26951332
    [TBL] [Abstract][Full Text] [Related]  

  • 13. All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells.
    Kim Y; Jeung HK; Cheong JW; Song J; Bae SH; Lee JI; Min YH
    Yonsei Med J; 2020 Sep; 61(9):762-773. PubMed ID: 32882760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.
    Weisberg SP; Smith-Raska MR; Esquilin JM; Zhang J; Arenzana TL; Lau CM; Churchill M; Pan H; Klinakis A; Dixon JE; Mirny LA; Mukherjee S; Reizis B
    Cell Rep; 2014 Feb; 6(3):528-40. PubMed ID: 24485662
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.
    Huang H; Jiang X; Wang J; Li Y; Song CX; Chen P; Li S; Gurbuxani S; Arnovitz S; Wang Y; Weng H; Neilly MB; He C; Li Z; Chen J
    Cancer Lett; 2016 Mar; 372(2):157-65. PubMed ID: 26791235
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia.
    Goswami S; Mani R; Nunes J; Chiang CL; Zapolnik K; Hu E; Frissora F; Mo X; Walker LA; Yan P; Bundschuh R; Beaver L; Devine R; Tsai YT; Ventura A; Xie Z; Chen M; Lapalombella R; Walker A; Mims A; Larkin K; Grieselhuber N; Bennett C; Phelps M; Hertlein E; Behbehani G; Vasu S; Byrd JC; Muthusamy N
    Blood; 2022 Mar; 139(9):1340-1358. PubMed ID: 34788382
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility.
    Hou HA; Tien HF
    Expert Rev Hematol; 2016 May; 9(5):447-69. PubMed ID: 26789100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of IDH mutations in acute myeloid leukemia.
    Montalban-Bravo G; DiNardo CD
    Future Oncol; 2018 Apr; 14(10):979-993. PubMed ID: 29543066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. l-Asparaginase-mediated downregulation of c-Myc promotes 1,25(OH)
    Song JH; Park E; Kim MS; Cho KM; Park SH; Lee A; Song J; Kim HJ; Koh JT; Kim TS
    Int J Cancer; 2017 May; 140(10):2364-2374. PubMed ID: 28224619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Additional mutations in IDH1/2-mutated patients with acute myeloid leukemia.
    Lu J; Chen M; Hua H; Qin W; Zhang R; Lu X; Chao H
    Int J Lab Hematol; 2021 Dec; 43(6):1483-1490. PubMed ID: 34270876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.