216 related articles for article (PubMed ID: 33865867)
1. Degradation of Alzheimer's Amyloid-β by a Catalytically Inactive Insulin-Degrading Enzyme.
Sahoo BR; Panda PK; Liang W; Tang WJ; Ahuja R; Ramamoorthy A
J Mol Biol; 2021 Jun; 433(13):166993. PubMed ID: 33865867
[TBL] [Abstract][Full Text] [Related]
2. Toward Allosterically Increased Catalytic Activity of Insulin-Degrading Enzyme against Amyloid Peptides.
Kurochkin IV; Guarnera E; Wong JH; Eisenhaber F; Berezovsky IN
Biochemistry; 2017 Jan; 56(1):228-239. PubMed ID: 27982586
[TBL] [Abstract][Full Text] [Related]
3. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme.
Vekrellis K; Ye Z; Qiu WQ; Walsh D; Hartley D; Chesneau V; Rosner MR; Selkoe DJ
J Neurosci; 2000 Mar; 20(5):1657-65. PubMed ID: 10684867
[TBL] [Abstract][Full Text] [Related]
4. Modulation of the Activity of the Insulin-Degrading Enzyme by Aβ Peptides.
Kemeh MM; Lazo ND
ACS Chem Neurosci; 2023 Aug; 14(16):2935-2943. PubMed ID: 37498802
[TBL] [Abstract][Full Text] [Related]
5. Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin.
Betts V; Leissring MA; Dolios G; Wang R; Selkoe DJ; Walsh DM
Neurobiol Dis; 2008 Sep; 31(3):442-50. PubMed ID: 18602473
[TBL] [Abstract][Full Text] [Related]
6. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.
Guo Q; Manolopoulou M; Bian Y; Schilling AB; Tang WJ
J Mol Biol; 2010 Jan; 395(2):430-43. PubMed ID: 19896952
[TBL] [Abstract][Full Text] [Related]
7. The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis.
Llovera RE; de Tullio M; Alonso LG; Leissring MA; Kaufman SB; Roher AE; de Prat Gay G; Morelli L; Castaño EM
J Biol Chem; 2008 Jun; 283(25):17039-48. PubMed ID: 18411275
[TBL] [Abstract][Full Text] [Related]
8. Copper(I) and copper(II) inhibit Aβ peptides proteolysis by insulin-degrading enzyme differently: implications for metallostasis alteration in Alzheimer's disease.
Grasso G; Pietropaolo A; Spoto G; Pappalardo G; Tundo GR; Ciaccio C; Coletta M; Rizzarelli E
Chemistry; 2011 Feb; 17(9):2752-62. PubMed ID: 21274957
[TBL] [Abstract][Full Text] [Related]
9. Elucidation of interactions of Alzheimer amyloid beta peptides (Abeta40 and Abeta42) with insulin degrading enzyme: a molecular dynamics study.
Bora RP; Prabhakar R
Biochemistry; 2010 May; 49(18):3947-56. PubMed ID: 20380468
[TBL] [Abstract][Full Text] [Related]
10. Medium-Chain Length Fatty Acids Enhance Aβ Degradation by Affecting Insulin-Degrading Enzyme.
Mett J; Lauer AA; Janitschke D; Griebsch LV; Theiss EL; Grimm HS; Koivisto H; Tanila H; Hartmann T; Grimm MOW
Cells; 2021 Oct; 10(11):. PubMed ID: 34831163
[TBL] [Abstract][Full Text] [Related]
11. Insulin-degrading enzyme in brain microvessels: proteolysis of amyloid {beta} vasculotropic variants and reduced activity in cerebral amyloid angiopathy.
Morelli L; Llovera RE; Mathov I; Lue LF; Frangione B; Ghiso J; Castaño EM
J Biol Chem; 2004 Dec; 279(53):56004-13. PubMed ID: 15489232
[TBL] [Abstract][Full Text] [Related]
12. Purified recombinant insulin-degrading enzyme degrades amyloid beta-protein but does not promote its oligomerization.
Chesneau V; Vekrellis K; Rosner MR; Selkoe DJ
Biochem J; 2000 Oct; 351 Pt 2(Pt 2):509-16. PubMed ID: 11023838
[TBL] [Abstract][Full Text] [Related]
13. Quantitative NMR Study of Insulin-Degrading Enzyme Using Amyloid-β and HIV-1 p6 Elucidates Its Chaperone Activity.
Ramaraju B; Nelson SL; Zheng W; Ghirlando R; Deshmukh L
Biochemistry; 2021 Aug; 60(33):2519-2523. PubMed ID: 34342986
[TBL] [Abstract][Full Text] [Related]
14. Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states.
Hubin E; Cioffi F; Rozenski J; van Nuland NA; Broersen K
Biochim Biophys Acta; 2016 Jun; 1860(6):1281-90. PubMed ID: 26968463
[TBL] [Abstract][Full Text] [Related]
15. Insulysin: an allosteric enzyme as a target for Alzheimer's disease.
Song ES; Hersh LB
J Mol Neurosci; 2005; 25(3):201-6. PubMed ID: 15800373
[TBL] [Abstract][Full Text] [Related]
16. Somatostatin: a novel substrate and a modulator of insulin-degrading enzyme activity.
Ciaccio C; Tundo GR; Grasso G; Spoto G; Marasco D; Ruvo M; Gioia M; Rizzarelli E; Coletta M
J Mol Biol; 2009 Feb; 385(5):1556-67. PubMed ID: 19073193
[TBL] [Abstract][Full Text] [Related]
17. Multiple allosteric sites are involved in the modulation of insulin-degrading-enzyme activity by somatostatin.
Tundo GR; Di Muzio E; Ciaccio C; Sbardella D; Di Pierro D; Polticelli F; Coletta M; Marini S
FEBS J; 2016 Oct; 283(20):3755-3770. PubMed ID: 27579517
[TBL] [Abstract][Full Text] [Related]
18. Reduced amyloid-β degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models.
Stargardt A; Gillis J; Kamphuis W; Wiemhoefer A; Kooijman L; Raspe M; Benckhuijsen W; Drijfhout JW; Hol EM; Reits E
Aging Cell; 2013 Jun; 12(3):499-507. PubMed ID: 23534431
[TBL] [Abstract][Full Text] [Related]
19. BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).
Kilger E; Buehler A; Woelfing H; Kumar S; Kaeser SA; Nagarathinam A; Walter J; Jucker M; Coomaraswamy J
J Biol Chem; 2011 Oct; 286(43):37446-57. PubMed ID: 21873424
[TBL] [Abstract][Full Text] [Related]
20. Design of Peptide Substrate for Sensitively and Specifically Detecting Two Aβ-Degrading Enzymes: Neprilysin and Angiotensin-Converting Enzyme.
Chen PT; Chen CL; Lin LT; Lo CH; Hu CJ; Chen RP; Wang SS
PLoS One; 2016; 11(4):e0153360. PubMed ID: 27096746
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
