BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 33872193)

  • 1. SPRED proteins and their roles in signal transduction, development, and malignancy.
    Lorenzo C; McCormick F
    Genes Dev; 2020 Nov; 34(21-22):1410-1421. PubMed ID: 33872193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
    Yan W; Markegard E; Dharmaiah S; Urisman A; Drew M; Esposito D; Scheffzek K; Nissley DV; McCormick F; Simanshu DK
    Cell Rep; 2020 Jul; 32(3):107909. PubMed ID: 32697994
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pathogenic Mutations Associated with Legius Syndrome Modify the Spred1 Surface and Are Involved in Direct Binding to the Ras Inactivator Neurofibromin.
    Führer S; Tollinger M; Dunzendorfer-Matt T
    J Mol Biol; 2019 Sep; 431(19):3889-3899. PubMed ID: 31401120
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1.
    Hirata Y; Brems H; Suzuki M; Kanamori M; Okada M; Morita R; Llano-Rivas I; Ose T; Messiaen L; Legius E; Yoshimura A
    J Biol Chem; 2016 Feb; 291(7):3124-34. PubMed ID: 26635368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling.
    Lopez J; Bonsor DA; Sale MJ; Urisman A; Mehalko JL; Cabanski-Dunning M; Castel P; Simanshu DK; McCormick F
    J Biol Chem; 2023 Jun; 299(6):104789. PubMed ID: 37149146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Progress in experimental research on SPRED protein family.
    Gong J; Yan Z; Liu Q
    J Int Med Res; 2020 Aug; 48(8):300060520929170. PubMed ID: 32851895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The neurofibromin recruitment factor Spred1 binds to the GAP related domain without affecting Ras inactivation.
    Dunzendorfer-Matt T; Mercado EL; Maly K; McCormick F; Scheffzek K
    Proc Natl Acad Sci U S A; 2016 Jul; 113(27):7497-502. PubMed ID: 27313208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.
    Stowe IB; Mercado EL; Stowe TR; Bell EL; Oses-Prieto JA; Hernández H; Burlingame AL; McCormick F
    Genes Dev; 2012 Jul; 26(13):1421-6. PubMed ID: 22751498
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct requirements for the Sprouty domain for functional activity of Spred proteins.
    King JA; Straffon AF; D'Abaco GM; Poon CL; I ST; Smith CM; Buchert M; Corcoran NM; Hall NE; Callus BA; Sarcevic B; Martin D; Lock P; Hovens CM
    Biochem J; 2005 Jun; 388(Pt 2):445-54. PubMed ID: 15683364
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SPRED1, a RAS MAPK pathway inhibitor that causes Legius syndrome, is a tumour suppressor downregulated in paediatric acute myeloblastic leukaemia.
    Pasmant E; Gilbert-Dussardier B; Petit A; de Laval B; Luscan A; Gruber A; Lapillonne H; Deswarte C; Goussard P; Laurendeau I; Uzan B; Pflumio F; Brizard F; Vabres P; Naguibvena I; Fasola S; Millot F; Porteu F; Vidaud D; Landman-Parker J; Ballerini P
    Oncogene; 2015 Jan; 34(5):631-8. PubMed ID: 24469042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Legius syndrome, an Update. Molecular pathology of mutations in SPRED1.
    Brems H; Legius E
    Keio J Med; 2013; 62(4):107-12. PubMed ID: 24334617
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions.
    Li D; Jackson RA; Yusoff P; Guy GR
    J Biol Chem; 2010 Nov; 285(46):35374-85. PubMed ID: 20736167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MEK inhibition ameliorates social behavior phenotypes in a Spred1 knockout mouse model for RASopathy disorders.
    Borrie SC; Plasschaert E; Callaerts-Vegh Z; Yoshimura A; D'Hooge R; Elgersma Y; Kushner SA; Legius E; Brems H
    Mol Autism; 2021 Jul; 12(1):53. PubMed ID: 34311771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain-containing protein (SPRED1), a tyrosine-protein phosphatase non-receptor type 11 (SHP2) substrate in the Ras/extracellular signal-regulated kinase (ERK) pathway.
    Quintanar-Audelo M; Yusoff P; Sinniah S; Chandramouli S; Guy GR
    J Biol Chem; 2011 Jul; 286(26):23102-12. PubMed ID: 21531714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SPRED proteins provide a NF-ty link to Ras suppression.
    McClatchey AI; Cichowski K
    Genes Dev; 2012 Jul; 26(14):1515-9. PubMed ID: 22802525
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sprouty gain of function disrupts lens cellular processes and growth by restricting RTK signaling.
    Shin EH; Zhao G; Wang Q; Lovicu FJ
    Dev Biol; 2015 Oct; 406(2):129-46. PubMed ID: 26375880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spred is a Sprouty-related suppressor of Ras signalling.
    Wakioka T; Sasaki A; Kato R; Shouda T; Matsumoto A; Miyoshi K; Tsuneoka M; Komiya S; Baron R; Yoshimura A
    Nature; 2001 Aug; 412(6847):647-51. PubMed ID: 11493923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Sprouty/Spred family as tumor suppressors: Coming of age.
    Kawazoe T; Taniguchi K
    Cancer Sci; 2019 May; 110(5):1525-1535. PubMed ID: 30874331
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.
    Brems H; Chmara M; Sahbatou M; Denayer E; Taniguchi K; Kato R; Somers R; Messiaen L; De Schepper S; Fryns JP; Cools J; Marynen P; Thomas G; Yoshimura A; Legius E
    Nat Genet; 2007 Sep; 39(9):1120-6. PubMed ID: 17704776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling.
    Siljamäki E; Abankwa D
    Mol Cell Biol; 2016 Oct; 36(20):2612-25. PubMed ID: 27503857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.