These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
159 related articles for article (PubMed ID: 33879017)
1. Deep-learning based repurposing of FDA-approved drugs against Joshi T; Pundir H; Chandra S J Biomol Struct Dyn; 2022 Nov; 40(18):8420-8436. PubMed ID: 33879017 [No Abstract] [Full Text] [Related]
2. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Paulsen JL; Bendel SD; Anderson AC Chem Biol Drug Des; 2011 Oct; 78(4):505-12. PubMed ID: 21726415 [TBL] [Abstract][Full Text] [Related]
3. Repurposing of FDA approved drugs against Joshi T; Sharma P; Joshi T; Mathpal S; Pande V; Chandra S J Biomol Struct Dyn; 2022 May; 40(8):3731-3744. PubMed ID: 33251976 [TBL] [Abstract][Full Text] [Related]
4. Target-based drug repurposing against Candida albicans-A computational modeling, docking, and molecular dynamic simulations study. Verma R; Pradhan D; Nayek A; Singh H; Jain AK; Khan LA J Cell Biochem; 2022 Feb; 123(2):289-305. PubMed ID: 34672012 [TBL] [Abstract][Full Text] [Related]
5. Dihydrofolate Reductase Is a Valid Target for Antifungal Development in the Human Pathogen DeJarnette C; Luna-Tapia A; Estredge LR; Palmer GE mSphere; 2020 Jun; 5(3):. PubMed ID: 32581079 [TBL] [Abstract][Full Text] [Related]
6. Repurposing benzbromarone as antifolate to develop novel antifungal therapy for Candida albicans. Mujwar S; Tripathi A J Mol Model; 2022 Jun; 28(7):193. PubMed ID: 35716240 [TBL] [Abstract][Full Text] [Related]
7. Repurposing FDA-approved drugs to target malaria through inhibition of dihydrofolate reductase in the folate biosynthesis pathway: A prospective approach. Verma K; Chaturvedi R; Lahariya AK; Verma AK; Schneider KA; Anvikar AR; Bharti PK J Cell Biochem; 2024 Mar; 125(3):e30533. PubMed ID: 38345373 [TBL] [Abstract][Full Text] [Related]
9. Halogenated derivatives of methotrexate as human dihydrofolate reductase inhibitors in cancer chemotherapy. Uddin N; Ahmed S; Khan AM; Mazharol Hoque M; Halim MA J Biomol Struct Dyn; 2020 Feb; 38(3):901-917. PubMed ID: 30938661 [TBL] [Abstract][Full Text] [Related]
11. Applications of Receptor- and Ligand-based Models in Inverse Docking Experiments: Recognition of Dihydrofolate Reductase Using 7,8-Dialkyl- 1,3-Diaminopyrrolo[3,2-f]Quinazolines. Kumar SP; Jasrai YT; Pandya HA Curr Comput Aided Drug Des; 2016; 12(1):15-28. PubMed ID: 26725591 [TBL] [Abstract][Full Text] [Related]
12. Selectivity analysis of 5-(arylthio)-2,4-diaminoquinazolines as inhibitors of Candida albicans dihydrofolate reductase by molecular dynamics simulations. Gokhale VM; Kulkarni VM J Comput Aided Mol Des; 2000 Jul; 14(5):495-506. PubMed ID: 10896321 [TBL] [Abstract][Full Text] [Related]
13. Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans. Kim K; Zilbermintz L; Martchenko M Ann Clin Microbiol Antimicrob; 2015 Jun; 14():32. PubMed ID: 26054754 [TBL] [Abstract][Full Text] [Related]
14. In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug Resistant Human Dihydrofolate Reductase for Cancer Therapeutics. Rana RM; Rampogu S; Abid NB; Zeb A; Parate S; Lee G; Yoon S; Kim Y; Kim D; Lee KW Molecules; 2020 Jul; 25(15):. PubMed ID: 32752079 [TBL] [Abstract][Full Text] [Related]
15. Virtual screening and drug repositioning as strategies for the discovery of new antifungal inhibitors of oxidosqualene cyclase. Rabelo VW; Viegas DJ; Tucci EMN; Romeiro NC; Abreu PA J Steroid Biochem Mol Biol; 2019 Jan; 185():189-199. PubMed ID: 30193921 [TBL] [Abstract][Full Text] [Related]
16. In Silico Drug Repurposing Approach: Investigation of Ngidi NTP; Machaba KE; Mhlongo NN Molecules; 2022 Jan; 27(3):. PubMed ID: 35163931 [No Abstract] [Full Text] [Related]
17. Insights on the anticandidal activity of non-antifungal drugs. Moraes DC; Ferreira-Pereira A J Mycol Med; 2019 Sep; 29(3):253-259. PubMed ID: 31399349 [TBL] [Abstract][Full Text] [Related]
18. Anti-Fungal Potential of Structurally Diverse FDA-Approved Therapeutics Targeting Secreted Aspartyl Proteinase (SAP) of Candida albicans: an In Silico Drug Repurposing Approach. Dhanasekaran S; Selvadoss PP; Manoharan SS Appl Biochem Biotechnol; 2023 Mar; 195(3):1983-1998. PubMed ID: 36401722 [TBL] [Abstract][Full Text] [Related]
19. In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans. Paulsen JL; Liu J; Bolstad DB; Smith AE; Priestley ND; Wright DL; Anderson AC Bioorg Med Chem; 2009 Jul; 17(14):4866-72. PubMed ID: 19560363 [TBL] [Abstract][Full Text] [Related]
20. Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata. G-Dayanandan N; Paulsen JL; Viswanathan K; Keshipeddy S; Lombardo MN; Zhou W; Lamb KM; Sochia AE; Alverson JB; Priestley ND; Wright DL; Anderson AC J Med Chem; 2014 Mar; 57(6):2643-56. PubMed ID: 24568657 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]