These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 33882930)

  • 1. Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity.
    Wang H; Liang J; Yue Q; Li L; Shi Y; Chen G; Li YZ; Bian X; Zhang Y; Zhao G; Ding X
    Microb Cell Fact; 2021 Apr; 20(1):86. PubMed ID: 33882930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
    Tang L; Yoon YJ; Choi CY; Hutchinson CR
    Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase.
    Petković H; Sandmann A; Challis IR; Hecht HJ; Silakowski B; Low L; Beeston N; Kuscer E; Garcia-Bernardo J; Leadlay PF; Kendrew SG; Wilkinson B; Müller R
    Org Biomol Chem; 2008 Feb; 6(3):500-6. PubMed ID: 18219420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY; Alekseyev VY; Chen AY; Tang Y; Cane DE; Khosla C
    Biochemistry; 2004 Nov; 43(44):13892-8. PubMed ID: 15518537
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase.
    Sabatini M; Comba S; Altabe S; Recio-Balsells AI; Labadie GR; Takano E; Gramajo H; Arabolaza A
    FEBS J; 2018 Dec; 285(23):4494-4511. PubMed ID: 30300504
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enzymatic assembly of epothilones: the EpoC subunit and reconstitution of the EpoA-ACP/B/C polyketide and nonribosomal peptide interfaces.
    O'Connor SE; Chen H; Walsh CT
    Biochemistry; 2002 Apr; 41(17):5685-94. PubMed ID: 11969430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms of molecular recognition in the pikromycin polyketide synthase.
    Chen S; Xue Y; Sherman DH; Reynolds KA
    Chem Biol; 2000 Dec; 7(12):907-18. PubMed ID: 11137814
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase.
    Jiralerspong S; Rangaswamy V; Bender CL; Parry RJ
    Gene; 2001 May; 270(1-2):191-200. PubMed ID: 11404016
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation of new epothilones by genetic engineering of a polyketide synthase in Myxococcus xanthus.
    Tang L; Chung L; Carney JR; Starks CM; Licari P; Katz L
    J Antibiot (Tokyo); 2005 Mar; 58(3):178-84. PubMed ID: 15895525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A polylinker approach to reductive loop swaps in modular polyketide synthases.
    Kellenberger L; Galloway IS; Sauter G; Böhm G; Hanefeld U; Cortés J; Staunton J; Leadlay PF
    Chembiochem; 2008 Nov; 9(16):2740-9. PubMed ID: 18937219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study.
    Anand S; Mohanty D
    BMC Struct Biol; 2012 May; 12():10. PubMed ID: 22639887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production.
    Yuzawa S; Deng K; Wang G; Baidoo EE; Northen TR; Adams PD; Katz L; Keasling JD
    ACS Synth Biol; 2017 Jan; 6(1):139-147. PubMed ID: 27548700
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic analysis of acyl transferase domain exchange in polyketide synthase modules.
    Hans M; Hornung A; Dziarnowski A; Cane DE; Khosla C
    J Am Chem Soc; 2003 May; 125(18):5366-74. PubMed ID: 12720450
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases.
    Ostrowski MP; Cane DE; Khosla C
    J Antibiot (Tokyo); 2016 Jul; 69(7):507-10. PubMed ID: 27118242
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural rearrangements of a polyketide synthase module during its catalytic cycle.
    Whicher JR; Dutta S; Hansen DA; Hale WA; Chemler JA; Dosey AM; Narayan AR; Håkansson K; Sherman DH; Smith JL; Skiniotis G
    Nature; 2014 Jun; 510(7506):560-4. PubMed ID: 24965656
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases.
    Zhang L; Ji J; Yuan M; Feng Y; Wang L; Deng Z; Bai L; Zheng J
    ACS Chem Biol; 2018 Apr; 13(4):871-875. PubMed ID: 29437374
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
    Lohman JR; Ma M; Osipiuk J; Nocek B; Kim Y; Chang C; Cuff M; Mack J; Bigelow L; Li H; Endres M; Babnigg G; Joachimiak A; Phillips GN; Shen B
    Proc Natl Acad Sci U S A; 2015 Oct; 112(41):12693-8. PubMed ID: 26420866
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Extender unit and acyl carrier protein specificity of ketosynthase domains of the 6-deoxyerythronolide B synthase.
    Chen AY; Schnarr NA; Kim CY; Cane DE; Khosla C
    J Am Chem Soc; 2006 Mar; 128(9):3067-74. PubMed ID: 16506788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chain initiation on the soraphen-producing modular polyketide synthase from Sorangium cellulosum.
    Wilkinson CJ; Frost EJ; Staunton J; Leadlay PF
    Chem Biol; 2001 Dec; 8(12):1197-208. PubMed ID: 11755398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.