BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 33886552)

  • 1. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.
    Arveseth CD; Happ JT; Hedeen DS; Zhu JF; Capener JL; Klatt Shaw D; Deshpande I; Liang J; Xu J; Stubben SL; Nelson IB; Walker MF; Kawakami K; Inoue A; Krogan NJ; Grunwald DJ; Hüttenhain R; Manglik A; Myers BR
    PLoS Biol; 2021 Apr; 19(4):e3001191. PubMed ID: 33886552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.
    Happ JT; Arveseth CD; Bruystens J; Bertinetti D; Nelson IB; Olivieri C; Zhang J; Hedeen DS; Zhu JF; Capener JL; Bröckel JW; Vu L; King CC; Ruiz-Perez VL; Ge X; Veglia G; Herberg FW; Taylor SS; Myers BR
    Nat Struct Mol Biol; 2022 Oct; 29(10):990-999. PubMed ID: 36202993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase.
    Li S; Li S; Han Y; Tong C; Wang B; Chen Y; Jiang J
    PLoS Biol; 2016 Jun; 14(6):e1002481. PubMed ID: 27280464
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened.
    Zhao Z; Lee RT; Pusapati GV; Iyu A; Rohatgi R; Ingham PW
    EMBO Rep; 2016 May; 17(5):739-52. PubMed ID: 27113758
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dose-dependent transduction of Hedgehog relies on phosphorylation-based feedback between the G-protein-coupled receptor Smoothened and the kinase Fused.
    Sanial M; Bécam I; Hofmann L; Behague J; Argüelles C; Gourhand V; Bruzzone L; Holmgren RA; Plessis A
    Development; 2017 May; 144(10):1841-1850. PubMed ID: 28360132
    [TBL] [Abstract][Full Text] [Related]  

  • 6. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling.
    Ogden SK; Fei DL; Schilling NS; Ahmed YF; Hwa J; Robbins DJ
    Nature; 2008 Dec; 456(7224):967-70. PubMed ID: 18987629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The contributions of protein kinase A and smoothened phosphorylation to hedgehog signal transduction in Drosophila melanogaster.
    Zhou Q; Apionishev S; Kalderon D
    Genetics; 2006 Aug; 173(4):2049-62. PubMed ID: 16783001
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
    Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
    PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
    [TBL] [Abstract][Full Text] [Related]  

  • 9. G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
    Pusapati GV; Kong JH; Patel BB; Gouti M; Sagner A; Sircar R; Luchetti G; Ingham PW; Briscoe J; Rohatgi R
    Sci Signal; 2018 Feb; 11(516):. PubMed ID: 29438014
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of Smoothened in the Hedgehog pathway unexpectedly increases Gα
    Praktiknjo SD; Saad F; Maier D; Ip P; Hipfner DR
    J Biol Chem; 2018 Aug; 293(35):13496-13508. PubMed ID: 30018136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway.
    Ma G; Li S; Han Y; Li S; Yue T; Wang B; Jiang J
    Dev Cell; 2016 Nov; 39(4):438-451. PubMed ID: 27746045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequential phosphorylation of smoothened transduces graded hedgehog signaling.
    Su Y; Ospina JK; Zhang J; Michelson AP; Schoen AM; Zhu AJ
    Sci Signal; 2011 Jul; 4(180):ra43. PubMed ID: 21730325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade.
    Walker MF; Zhang J; Steiner W; Ku PI; Zhu JF; Michaelson Z; Yen YC; Lee A; Long AB; Casey MJ; Poddar A; Nelson IB; Arveseth CD; Nagel F; Clough R; LaPotin S; Kwan KM; Schulz S; Stewart RA; Tesmer JJG; Caspary T; Subramanian R; Ge X; Myers BR
    bioRxiv; 2024 Apr; ():. PubMed ID: 37214942
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction.
    Gorojankina T
    Cell Mol Life Sci; 2016 Apr; 73(7):1317-32. PubMed ID: 26762301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels.
    Singh J; Wen X; Scales SJ
    J Biol Chem; 2015 Dec; 290(49):29663-75. PubMed ID: 26451044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
    Lee H; Ko HW
    Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Drosophila G-protein-coupled receptor kinase 2 regulates cAMP-dependent Hedgehog signaling.
    Cheng S; Maier D; Hipfner DR
    Development; 2012 Jan; 139(1):85-94. PubMed ID: 22096079
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smoothened-dependent and -independent pathways in mammalian noncanonical Hedgehog signaling.
    Faria AVS; Akyala AI; Parikh K; Brüggemann LW; Spek CA; Cao W; Bruno MJ; Bijlsma MF; Fuhler GM; Peppelenbosch MP
    J Biol Chem; 2019 Jun; 294(25):9787-9798. PubMed ID: 30992365
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
    Chong YC; Mann RK; Zhao C; Kato M; Beachy PA
    Genes Dev; 2015 Feb; 29(3):262-76. PubMed ID: 25644602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.