BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 33887226)

  • 1. Dual arginine recognition of LRRK2 phosphorylated Rab GTPases.
    Waschbüsch D; Purlyte E; Khan AR
    Biophys J; 2021 May; 120(9):1846-1855. PubMed ID: 33887226
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2.
    Waschbüsch D; Purlyte E; Pal P; McGrath E; Alessi DR; Khan AR
    Structure; 2020 Apr; 28(4):406-417.e6. PubMed ID: 32017888
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LRRK2 phosphorylation of Rab GTPases in Parkinson's disease.
    Pfeffer SR
    FEBS Lett; 2023 Mar; 597(6):811-818. PubMed ID: 36114007
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner
    McGrath E; Waschbüsch D; Baker BM; Khan AR
    Small GTPases; 2021 Mar; 12(2):133-146. PubMed ID: 31552791
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade.
    Dhekne HS; Yanatori I; Vides EG; Sobu Y; Diez F; Tonelli F; Pfeffer SR
    Life Sci Alliance; 2021 May; 4(5):. PubMed ID: 33727250
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration.
    Jeong GR; Jang EH; Bae JR; Jun S; Kang HC; Park CH; Shin JH; Yamamoto Y; Tanaka-Yamamoto K; Dawson VL; Dawson TM; Hur EM; Lee BD
    Mol Neurodegener; 2018 Feb; 13(1):8. PubMed ID: 29439717
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of phospho-specific Rab protein antibodies to monitor
    Lis P; Burel S; Steger M; Mann M; Brown F; Diez F; Tonelli F; Holton JL; Ho PW; Ho SL; Chou MY; Polinski NK; Martinez TN; Davies P; Alessi DR
    Biochem J; 2018 Jan; 475(1):1-22. PubMed ID: 29127256
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
    Steger M; Diez F; Dhekne HS; Lis P; Nirujogi RS; Karayel O; Tonelli F; Martinez TN; Lorentzen E; Pfeffer SR; Alessi DR; Mann M
    Elife; 2017 Nov; 6():. PubMed ID: 29125462
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms.
    Malik AU; Karapetsas A; Nirujogi RS; Mathea S; Chatterjee D; Pal P; Lis P; Taylor M; Purlyte E; Gourlay R; Dorward M; Weidlich S; Toth R; Polinski NK; Knapp S; Tonelli F; Alessi DR
    Biochem J; 2021 Feb; 478(3):553-578. PubMed ID: 33459343
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LRRK2 and Rab GTPases.
    Pfeffer SR
    Biochem Soc Trans; 2018 Dec; 46(6):1707-1712. PubMed ID: 30467121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of Rab GTPases in the regulation of membrane trafficking.
    Waschbüsch D; Khan AR
    Traffic; 2020 Nov; 21(11):712-719. PubMed ID: 32969543
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for the specificity of PPM1H phosphatase for Rab GTPases.
    Waschbüsch D; Berndsen K; Lis P; Knebel A; Lam YP; Alessi DR; Khan AR
    EMBO Rep; 2021 Nov; 22(11):e52675. PubMed ID: 34580980
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
    Steger M; Tonelli F; Ito G; Davies P; Trost M; Vetter M; Wachter S; Lorentzen E; Duddy G; Wilson S; Baptista MA; Fiske BK; Fell MJ; Morrow JA; Reith AD; Alessi DR; Mann M
    Elife; 2016 Jan; 5():. PubMed ID: 26824392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. X Caps the Phosphate for Phospho-Rab GTPase Recognition in Ciliogenesis and Parkinson's Disease.
    Struck MW; Pazour GJ; Lambright DG
    Structure; 2020 Apr; 28(4):385-387. PubMed ID: 32268075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation.
    Fasiczka R; Naaldijk Y; Brahmia B; Hilfiker S
    Biochem Soc Trans; 2023 Apr; 51(2):587-595. PubMed ID: 36929701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2-mediated phosphorylation at Threonine72.
    Vieweg S; Mulholland K; Bräuning B; Kachariya N; Lai YC; Toth R; Singh PK; Volpi I; Sattler M; Groll M; Itzen A; Muqit MMK
    Biochem J; 2020 May; 477(9):1651-1668. PubMed ID: 32227113
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of a multiplexed targeted mass spectrometry assay for LRRK2-phosphorylated Rabs and Ser910/Ser935 biomarker sites.
    Nirujogi RS; Tonelli F; Taylor M; Lis P; Zimprich A; Sammler E; Alessi DR
    Biochem J; 2021 Jan; 478(2):299-326. PubMed ID: 33367571
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation.
    Vides EG; Adhikari A; Chiang CY; Lis P; Purlyte E; Limouse C; Shumate JL; Spínola-Lasso E; Dhekne HS; Alessi DR; Pfeffer SR
    Elife; 2022 Sep; 11():. PubMed ID: 36149401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Role of LRRK2 in Intracellular Organelle Dynamics.
    Boecker CA
    J Mol Biol; 2023 Jun; 435(12):167998. PubMed ID: 36764357
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.
    Berndsen K; Lis P; Yeshaw WM; Wawro PS; Nirujogi RS; Wightman M; Macartney T; Dorward M; Knebel A; Tonelli F; Pfeffer SR; Alessi DR
    Elife; 2019 Oct; 8():. PubMed ID: 31663853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.