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2. Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: implications for clinical use and genetic discovery efforts in human disease. Ebbert MTW; Farrugia SL; Sens JP; Jansen-West K; Gendron TF; Prudencio M; McLaughlin IJ; Bowman B; Seetin M; DeJesus-Hernandez M; Jackson J; Brown PH; Dickson DW; van Blitterswijk M; Rademakers R; Petrucelli L; Fryer JD Mol Neurodegener; 2018 Aug; 13(1):46. PubMed ID: 30126445 [TBL] [Abstract][Full Text] [Related]
3. Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72. van Blitterswijk M; Gendron TF; Baker MC; DeJesus-Hernandez M; Finch NA; Brown PH; Daughrity LM; Murray ME; Heckman MG; Jiang J; Lagier-Tourenne C; Edbauer D; Cleveland DW; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Petrucelli L; Boeve BF; Graff-Radford NR; Boylan KB; Dickson DW; Rademakers R Acta Neuropathol; 2015 Dec; 130(6):863-76. PubMed ID: 26437865 [TBL] [Abstract][Full Text] [Related]
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6. Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers. Jackson JL; Finch NA; Baker MC; Kachergus JM; DeJesus-Hernandez M; Pereira K; Christopher E; Prudencio M; Heckman MG; Thompson EA; Dickson DW; Shah J; Oskarsson B; Petrucelli L; Rademakers R; van Blitterswijk M Mol Neurodegener; 2020 Jan; 15(1):7. PubMed ID: 32000838 [TBL] [Abstract][Full Text] [Related]
7. Validation of a Long-Read PCR Assay for Sensitive Detection and Sizing of C9orf72 Hexanucleotide Repeat Expansions. Suh E; Grando K; Van Deerlin VM J Mol Diagn; 2018 Nov; 20(6):871-882. PubMed ID: 30138726 [TBL] [Abstract][Full Text] [Related]
8. Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome. Vourc'h P; Wurmser F; Brulard C; Mouzat K; Kassem S; Dangoumau A; Laumonnier F; Blasco H; Corcia P; Andres CR Neurobiol Aging; 2021 Jan; 97():148.e1-148.e7. PubMed ID: 32843153 [TBL] [Abstract][Full Text] [Related]
9. Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion. Waite AJ; Bäumer D; East S; Neal J; Morris HR; Ansorge O; Blake DJ Neurobiol Aging; 2014 Jul; 35(7):1779.e5-1779.e13. PubMed ID: 24559645 [TBL] [Abstract][Full Text] [Related]
10. The association between repeat number in C9orf72 and phenotypic variability in Turkish patients with frontotemporal lobar degeneration. Erzurumluoglu E; Cilingir O; Ozbabalik Adapinar BD; Bilgic B; Kocagil S; Ozen H; Durak Aras B; Yenilmez C; Artan S Neurobiol Aging; 2019 Apr; 76():216.e1-216.e7. PubMed ID: 30685122 [TBL] [Abstract][Full Text] [Related]
11. Molecular Mechanisms of Neurodegeneration Related to Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737 [TBL] [Abstract][Full Text] [Related]
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13. Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72. Chiò A; Borghero G; Restagno G; Mora G; Drepper C; Traynor BJ; Sendtner M; Brunetti M; Ossola I; Calvo A; Pugliatti M; Sotgiu MA; Murru MR; Marrosu MG; Marrosu F; Marinou K; Mandrioli J; Sola P; Caponnetto C; Mancardi G; Mandich P; La Bella V; Spataro R; Conte A; Monsurrò MR; Tedeschi G; Pisano F; Bartolomei I; Salvi F; Lauria Pinter G; Simone I; Logroscino G; Gambardella A; Quattrone A; Lunetta C; Volanti P; Zollino M; Penco S; Battistini S; ; Renton AE; Majounie E; Abramzon Y; Conforti FL; Giannini F; Corbo M; Sabatelli M Brain; 2012 Mar; 135(Pt 3):784-93. PubMed ID: 22366794 [TBL] [Abstract][Full Text] [Related]
14. Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients. Jääskeläinen O; Solje E; Hall A; Katisko K; Korhonen V; Tiainen M; Kangas AJ; Helisalmi S; Pikkarainen M; Koivisto A; Hartikainen P; Hiltunen M; Ala-Korpela M; Soininen H; Soininen P; Haapasalo A; Remes AM; Herukka SK J Alzheimers Dis; 2019; 72(1):127-137. PubMed ID: 31561355 [TBL] [Abstract][Full Text] [Related]
15. In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers. DeJesus-Hernandez M; Finch NA; Wang X; Gendron TF; Bieniek KF; Heckman MG; Vasilevich A; Murray ME; Rousseau L; Weesner R; Lucido A; Parsons M; Chew J; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Boeve BF; Graff-Radford NR; de Boer J; Asmann YW; Petrucelli L; Boylan KB; Dickson DW; van Blitterswijk M; Rademakers R Acta Neuropathol; 2017 Aug; 134(2):255-269. PubMed ID: 28508101 [TBL] [Abstract][Full Text] [Related]
16. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions. Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876 [TBL] [Abstract][Full Text] [Related]
17. Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Mordes DA; Prudencio M; Goodman LD; Klim JR; Moccia R; Limone F; Pietilainen O; Chowdhary K; Dickson DW; Rademakers R; Bonini NM; Petrucelli L; Eggan K Acta Neuropathol Commun; 2018 Jul; 6(1):55. PubMed ID: 29973287 [TBL] [Abstract][Full Text] [Related]
18. Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72. Davidson YS; Barker H; Robinson AC; Thompson JC; Harris J; Troakes C; Smith B; Al-Saraj S; Shaw C; Rollinson S; Masuda-Suzukake M; Hasegawa M; Pickering-Brown S; Snowden JS; Mann DM Acta Neuropathol Commun; 2014 Jun; 2():70. PubMed ID: 24950788 [TBL] [Abstract][Full Text] [Related]
19. Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions. Cooper-Knock J; Walsh MJ; Higginbottom A; Robin Highley J; Dickman MJ; Edbauer D; Ince PG; Wharton SB; Wilson SA; Kirby J; Hautbergue GM; Shaw PJ Brain; 2014 Jul; 137(Pt 7):2040-51. PubMed ID: 24866055 [TBL] [Abstract][Full Text] [Related]
20. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis. Farg MA; Konopka A; Soo KY; Ito D; Atkin JD Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]