149 related articles for article (PubMed ID: 33901806)
1. Chemoenzymatic synthesis of 2,6-disubstituted tetrahydropyrans with high σ
Kopp N; Civenni G; Marson D; Laurini E; Pricl S; Catapano CV; Humpf HU; Almansa C; Nieto FR; Schepmann D; Wünsch B
Eur J Med Chem; 2021 Jul; 219():113443. PubMed ID: 33901806
[TBL] [Abstract][Full Text] [Related]
2. Medicinal Chemistry of σ
Weber F; Wünsch B
Handb Exp Pharmacol; 2017; 244():51-79. PubMed ID: 28620761
[TBL] [Abstract][Full Text] [Related]
3. Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure σ ligands with 2-benzopyran structure.
Knappmann I; Lehmkuhl K; Köhler J; Schepmann D; Giera M; Bracher F; Wünsch B
Bioorg Med Chem; 2017 Jul; 25(13):3384-3395. PubMed ID: 28501431
[TBL] [Abstract][Full Text] [Related]
4. Identification, pharmacological evaluation and binding mode analysis of novel chromene and chromane based σ1 receptor ligands.
Laurini E; Harel D; Marson D; Schepmann D; Schmidt TJ; Pricl S; Wünsch B
Eur J Med Chem; 2014 Aug; 83():526-33. PubMed ID: 24996139
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of conformationally restricted 1,3-dioxanes to analyze the bioactive conformation of 1,3-dioxane-based σ
Asare-Nkansah S; Schepmann D; Wünsch B
Bioorg Med Chem; 2017 Apr; 25(8):2472-2481. PubMed ID: 28320613
[TBL] [Abstract][Full Text] [Related]
6. Rigidity versus Flexibility: Is This an Issue in σ1 Receptor Ligand Affinity and Activity?
Weber F; Brune S; Börgel F; Lange C; Korpis K; Bednarski PJ; Laurini E; Fermeglia M; Pricl S; Schepmann D; Wünsch B
J Med Chem; 2016 Jun; 59(11):5505-19. PubMed ID: 27156565
[TBL] [Abstract][Full Text] [Related]
7. Computer-assisted design, synthesis, binding and cytotoxicity assessments of new 1-(4-(aryl(methyl)amino)butyl)-heterocyclic sigma 1 ligands.
Zampieri D; Vio L; Fermeglia M; Pricl S; Wünsch B; Schepmann D; Romano M; Mamolo MG; Laurini E
Eur J Med Chem; 2016 Oct; 121():712-726. PubMed ID: 27366902
[TBL] [Abstract][Full Text] [Related]
8. Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.
Xu R; Lord SA; Peterson RM; Fergason-Cantrell EA; Lever JR; Lever SZ
Bioorg Med Chem; 2015 Jan; 23(1):222-30. PubMed ID: 25468036
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and receptor binding studies of some new arylcarboxamide derivatives as sigma-1 ligands.
Zampieri D; Laurini E; Vio L; Golob S; Fermeglia M; Pricl S; Mamolo MG
Bioorg Med Chem Lett; 2014 Feb; 24(4):1021-5. PubMed ID: 24486131
[TBL] [Abstract][Full Text] [Related]
10. Novel Potent N-Methyl-d-aspartate (NMDA) Receptor Antagonists or σ1 Receptor Ligands Based on Properly Substituted 1,4-Dioxane Ring.
Bonifazi A; Del Bello F; Mammoli V; Piergentili A; Petrelli R; Cimarelli C; Pellei M; Schepmann D; Wünsch B; Barocelli E; Bertoni S; Flammini L; Amantini C; Nabissi M; Santoni G; Vistoli G; Quaglia W
J Med Chem; 2015 Nov; 58(21):8601-15. PubMed ID: 26430967
[TBL] [Abstract][Full Text] [Related]
11. Thiazole-Based σ
Kokornaczyk AK; Schepmann D; Yamaguchi J; Itami K; Laurini E; Fermeglia M; Pricl S; Wünsch B
ChemMedChem; 2017 Jul; 12(13):1070-1080. PubMed ID: 28544475
[TBL] [Abstract][Full Text] [Related]
12. Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel σ
Fanter L; Müller C; Schepmann D; Bracher F; Wünsch B
Bioorg Med Chem; 2017 Sep; 25(17):4778-4799. PubMed ID: 28764962
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and quantitative structure-activity relationships of N-(1-benzylpiperidin-4-yl)phenylacetamides and related analogues as potent and selective sigma1 receptor ligands.
Huang Y; Hammond PS; Whirrett BR; Kuhner RJ; Wu L; Childers SR; Mach RH
J Med Chem; 1998 Jun; 41(13):2361-70. PubMed ID: 9632369
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, pharmacological evaluation, and σ1 receptor interaction analysis of hydroxyethyl substituted piperazines.
Weber F; Brune S; Korpis K; Bednarski PJ; Laurini E; Dal Col V; Pricl S; Schepmann D; Wünsch B
J Med Chem; 2014 Apr; 57(7):2884-94. PubMed ID: 24617836
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of 4-(aminoalkyl) substituted 1,3-dioxanes as potent NMDA and σ receptor antagonists.
Utech T; Köhler J; Wünsch B
Eur J Med Chem; 2011 Jun; 46(6):2157-69. PubMed ID: 21444132
[TBL] [Abstract][Full Text] [Related]
16. Pharmacophore models and development of spirocyclic ligands for σ1 receptors.
Wunsch B
Curr Pharm Des; 2012; 18(7):930-7. PubMed ID: 22288413
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of (+)- and (-)-cis-2-[(1-adamantylamino)-methyl]-1-phenylcyclopropane derivatives as high affinity probes for sigma1 and sigma2 binding sites.
Marrazzo A; Prezzavento O; Pappalardo MS; Bousquet E; Iadanza M; Pike VW; Ronsisvalle G
Farmaco; 2002 Jan; 57(1):45-53. PubMed ID: 11902645
[TBL] [Abstract][Full Text] [Related]
18. 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives: novel, potent and selective sigma1 receptor ligands.
Ucar H; Cacciaguerra S; Spampinato S; Van derpoorten K; Isa M; Kanyonyo M; Poupaert JH
Eur J Pharmacol; 1997 Sep; 335(2-3):267-73. PubMed ID: 9369382
[TBL] [Abstract][Full Text] [Related]
19. Enantiomerically pure 1,3-dioxanes as highly selective NMDA and σ₁ receptor ligands.
Köhler J; Bergander K; Fabian J; Schepmann D; Wünsch B
J Med Chem; 2012 Oct; 55(20):8953-7. PubMed ID: 23013229
[TBL] [Abstract][Full Text] [Related]
20. Reevaluation of fenpropimorph as a σ receptor ligand: Structure-affinity relationship studies at human σ
Sguazzini E; Schmidt HR; Iyer KA; Kruse AC; Dukat M
Bioorg Med Chem Lett; 2017 Jul; 27(13):2912-2919. PubMed ID: 28495085
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]