These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 3390218)

  • 1. Methylenedioxy-benzopyran analogs of podophyllotoxin, a new synthetic class of antimitotic agents that inhibit tubulin polymerization.
    Batra JK; Kang GJ; Jurd L; Hamel E
    Biochem Pharmacol; 1988 Jul; 37(13):2595-602. PubMed ID: 3390218
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Morpholino derivatives of benzyl-benzodioxole, a study of structural requirements for drug interactions at the colchicine/podophyllotoxin binding site of tubulin.
    Batra JK; Jurd L; Hamel E
    Biochem Pharmacol; 1986 Nov; 35(22):4013-8. PubMed ID: 3778522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-function studies with derivatives of 6-benzyl-1,3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis.
    Batra JK; Jurd L; Hamel E
    Mol Pharmacol; 1985 Jan; 27(1):94-102. PubMed ID: 3965931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Lin CM; Singh SB; Chu PS; Dempcy RO; Schmidt JM; Pettit GR; Hamel E
    Mol Pharmacol; 1988 Aug; 34(2):200-8. PubMed ID: 3412321
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Derivatives of 5,6-diphenylpyridazin-3-one: synthetic antimitotic agents which interact with plant and mammalian tubulin at a new drug-binding site.
    Batra JK; Powers LJ; Hess FD; Hamel E
    Cancer Res; 1986 Apr; 46(4 Pt 2):1889-93. PubMed ID: 3948171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cornigerine, a potent antimitotic Colchicum alkaloid of unusual structure. Interactions with tubulin.
    Hamel E; Ho HH; Kang GJ; Lin CM
    Biochem Pharmacol; 1988 Jun; 37(12):2445-9. PubMed ID: 3390207
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antimitotic and antitubulin activity of the tumor inhibitor steganacin.
    Wang RW; Rebhum LI; Kupchan SM
    Cancer Res; 1977 Sep; 37(9):3071-9. PubMed ID: 560248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Lin CM; Ho HH; Pettit GR; Hamel E
    Biochemistry; 1989 Aug; 28(17):6984-91. PubMed ID: 2819042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polymerization of tubulin in the presence of colchicine or podophyllotoxin. Formation of a ribbon structure induced by guanylyl-5'-methylene diphosphonate.
    Sandoval IV; Weber K
    J Mol Biol; 1979 Oct; 134(1):159-72. PubMed ID: 537060
    [No Abstract]   [Full Text] [Related]  

  • 10. Effects of inhibitors of tubulin polymerization on GTP hydrolysis.
    Lin CM; Hamel E
    J Biol Chem; 1981 Sep; 256(17):9242-5. PubMed ID: 6114958
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Correlation of tubulin-binding and antitumor activities of podophyllotoxin analogs.
    Kelleher JK
    Cancer Treat Rep; 1978 Oct; 62(10):1443-7. PubMed ID: 101303
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tricyclic pyrone analogs: a new synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, microtubule assembly, the viability of leukemic cells in vitro and the growth of solid tumors in vivo.
    Perchellet EM; Ladesich JB; Magill MJ; Chen Y; Hua DH; Perchellet JP
    Anticancer Drugs; 1999 Jun; 10(5):489-504. PubMed ID: 10477169
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the interaction of the marine cyanobacterial natural product curacin A with the colchicine site of tubulin and initial structure-activity studies with analogues.
    Blokhin AV; Yoo HD; Geralds RS; Nagle DG; Gerwick WH; Hamel E
    Mol Pharmacol; 1995 Sep; 48(3):523-31. PubMed ID: 7565634
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
    Paull KD; Lin CM; Malspeis L; Hamel E
    Cancer Res; 1992 Jul; 52(14):3892-900. PubMed ID: 1617665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of 2-diazo-3,3,3-trifluopropanoyl derivatives of colchicine and podophyllotoxin as photoaffinity labels: reactivity, photochemistry, and tubulin binding.
    Hahn KM; Hastie SB; Sundberg RJ
    Photochem Photobiol; 1992 Jan; 55(1):17-27. PubMed ID: 1603847
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol.
    Pengsuparp T; Kingston DG; Neidigh KA; Cordell GA; Pezzuto JM
    Chem Biol Interact; 1996 Aug; 101(2):103-14. PubMed ID: 8760392
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of binding of the new antimitotic drug MDL 27048 to the colchicine site of tubulin: equilibrium studies.
    Peyrot V; Leynadier D; Sarrazin M; Briand C; Menendez M; Laynez J; Andreu JM
    Biochemistry; 1992 Nov; 31(45):11125-32. PubMed ID: 1445852
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Podophyllotoxin analogs. 1. Synthesis and biological evaluation of certain trans-2-aryl-trans-6-hydroxymethyl-3-cyclohexenecarboxylic acid gamma-lactones as antimitotic agents.
    Smissman EE; Murray RJ; McChesney JD; Houston LL; Pazdernik TL
    J Med Chem; 1976 Jan; 19(1):148-53. PubMed ID: 812990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin decay.
    Prasad V; Chaudhuri AR; Curcio M; Tomita I; Mizuhashi F; Murata K; Ludueña RF
    J Protein Chem; 1998 Oct; 17(7):663-8. PubMed ID: 9853681
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R; Cichacz ZA; Herald CL; Pettit GR; Hamel E
    Mol Pharmacol; 1993 Oct; 44(4):757-66. PubMed ID: 8232226
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.