334 related articles for article (PubMed ID: 33902624)
1. Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.
Mizrachi T; Marsha O; Brusin K; Ben-David Y; Thakur GA; Vaknin-Dembinsky A; Treinin M; Brenner T
J Neuroinflammation; 2021 Apr; 18(1):99. PubMed ID: 33902624
[TBL] [Abstract][Full Text] [Related]
2. The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.
Bagdas D; Wilkerson JL; Kulkarni A; Toma W; AlSharari S; Gul Z; Lichtman AH; Papke RL; Thakur GA; Damaj MI
Br J Pharmacol; 2016 Aug; 173(16):2506-20. PubMed ID: 27243753
[TBL] [Abstract][Full Text] [Related]
3. The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.
Papke RL; Horenstein NA; Kulkarni AR; Stokes C; Corrie LW; Maeng CY; Thakur GA
J Biol Chem; 2014 Feb; 289(7):4515-31. PubMed ID: 24362025
[TBL] [Abstract][Full Text] [Related]
4. Macroscopic and Microscopic Activation of
Quadri M; Garai S; Thakur GA; Stokes C; Gulsevin A; Horenstein NA; Papke RL
Mol Pharmacol; 2019 Jan; 95(1):43-61. PubMed ID: 30348894
[TBL] [Abstract][Full Text] [Related]
5. Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states.
Papke RL; Stokes C; Damaj MI; Thakur GA; Manther K; Treinin M; Bagdas D; Kulkarni AR; Horenstein NA
Br J Pharmacol; 2018 Jun; 175(11):1838-1854. PubMed ID: 28477386
[TBL] [Abstract][Full Text] [Related]
6. Allosteric Agonism of
Gulsevin A; Papke RL; Stokes C; Garai S; Thakur GA; Quadri M; Horenstein NA
Mol Pharmacol; 2019 Jun; 95(6):606-614. PubMed ID: 30944209
[TBL] [Abstract][Full Text] [Related]
7. Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses.
Nizri E; Irony-Tur-Sinai M; Lory O; Orr-Urtreger A; Lavi E; Brenner T
J Immunol; 2009 Nov; 183(10):6681-8. PubMed ID: 19846875
[TBL] [Abstract][Full Text] [Related]
8. Anti-inflammatory effects of astroglial α7 nicotinic acetylcholine receptors are mediated by inhibition of the NF-κB pathway and activation of the Nrf2 pathway.
Patel H; McIntire J; Ryan S; Dunah A; Loring R
J Neuroinflammation; 2017 Sep; 14(1):192. PubMed ID: 28950908
[TBL] [Abstract][Full Text] [Related]
9. Spinal activation of alpha7-nicotinic acetylcholine receptor attenuates posttraumatic stress disorder-related chronic pain via suppression of glial activation.
Sun R; Zhang W; Bo J; Zhang Z; Lei Y; Huo W; Liu Y; Ma Z; Gu X
Neuroscience; 2017 Mar; 344():243-254. PubMed ID: 28039041
[TBL] [Abstract][Full Text] [Related]
10. Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.
Horenstein NA; Papke RL; Kulkarni AR; Chaturbhuj GU; Stokes C; Manther K; Thakur GA
J Biol Chem; 2016 Mar; 291(10):5049-67. PubMed ID: 26742843
[TBL] [Abstract][Full Text] [Related]
11. Alpha-7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice.
Alzarea S; Rahman S
Behav Brain Res; 2019 Jul; 366():19-28. PubMed ID: 30877025
[TBL] [Abstract][Full Text] [Related]
12. The α7 nicotinic acetylcholine receptor positive allosteric modulator prevents lipopolysaccharide-induced allodynia, hyperalgesia and TNF-α in the hippocampus in mice.
Abbas M; Alzarea S; Papke RL; Rahman S
Pharmacol Rep; 2019 Dec; 71(6):1168-1176. PubMed ID: 31655281
[TBL] [Abstract][Full Text] [Related]
13. Distinctive Roles for α7*- and α9*-Nicotinic Acetylcholine Receptors in Inflammatory and Autoimmune Responses in the Murine Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis.
Liu Q; Whiteaker P; Morley BJ; Shi FD; Lukas RJ
Front Cell Neurosci; 2017; 11():287. PubMed ID: 29018331
[TBL] [Abstract][Full Text] [Related]
14. Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of
Papke RL; Garai S; Stokes C; Horenstein NA; Zimmerman AD; Abboud KA; Thakur GA
Mol Pharmacol; 2020 Oct; 98(4):292-302. PubMed ID: 32690627
[TBL] [Abstract][Full Text] [Related]
15. Neuroinflammation Modulation via α7 Nicotinic Acetylcholine Receptor and Its Chaperone, RIC-3.
Mizrachi T; Vaknin-Dembinsky A; Brenner T; Treinin M
Molecules; 2021 Oct; 26(20):. PubMed ID: 34684720
[TBL] [Abstract][Full Text] [Related]
16. Attenuation of CNS inflammatory responses by nicotine involves α7 and non-α7 nicotinic receptors.
Hao J; Simard AR; Turner GH; Wu J; Whiteaker P; Lukas RJ; Shi FD
Exp Neurol; 2011 Jan; 227(1):110-9. PubMed ID: 20932827
[TBL] [Abstract][Full Text] [Related]
17. A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE.
Godin JR; Roy P; Quadri M; Bagdas D; Toma W; Narendrula-Kotha R; Kishta OA; Damaj MI; Horenstein NA; Papke RL; Simard AR
Brain Behav Immun; 2020 Jul; 87():286-300. PubMed ID: 31874200
[TBL] [Abstract][Full Text] [Related]
18. Dose-dependent effects of GAT107, a novel allosteric agonist-positive allosteric modulator (ago-PAM) for the α7 nicotinic cholinergic receptor: a BOLD phMRI and connectivity study on awake rats.
Brems BM; Sullivan EE; Connolly JG; Zhang J; Chang A; Ortiz R; Cantwell L; Kulkarni P; Thakur GA; Ferris CF
Front Neurosci; 2023; 17():1196786. PubMed ID: 37424993
[TBL] [Abstract][Full Text] [Related]
19. Pitavastatin ameliorates autoimmune neuroinflammation by regulating the Treg/Th17 cell balance through inhibition of mevalonate metabolism.
Prado DS; Damasceno LEA; Sonego AB; Rosa MH; Martins TV; Fonseca MDM; Cunha TM; Cunha FQ; Alves-Filho JC
Int Immunopharmacol; 2021 Feb; 91():107278. PubMed ID: 33341737
[TBL] [Abstract][Full Text] [Related]
20. Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages.
Tan Y; Chu Z; Shan H; Zhangsun D; Zhu X; Luo S
Mar Drugs; 2022 Mar; 20(3):. PubMed ID: 35323499
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]