These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 33903987)

  • 1. Comparison of Hepatic Transporter Tissue Expression in Rodents and Interspecies Hepatic OCT1 Activity.
    Morse BL; Fallon JK; Kolur A; Hogan AT; Smith PC; Hillgren KM
    AAPS J; 2021 Apr; 23(3):58. PubMed ID: 33903987
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacokinetics of Organic Cation Transporter 1 (OCT1) Substrates in Oct1/2 Knockout Mice and Species Difference in Hepatic OCT1-Mediated Uptake.
    Morse BL; Kolur A; Hudson LR; Hogan AT; Chen LH; Brackman RM; Sawada GA; Fallon JK; Smith PC; Hillgren KM
    Drug Metab Dispos; 2020 Feb; 48(2):93-105. PubMed ID: 31771949
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Successful Prediction of Positron Emission Tomography-Imaged Metformin Hepatic Uptake Clearance in Humans Using the Quantitative Proteomics-Informed Relative Expression Factor Approach.
    Sachar M; Kumar V; Gormsen LC; Munk OL; Unadkat JD
    Drug Metab Dispos; 2020 Nov; 48(11):1210-1216. PubMed ID: 32843330
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1.
    Higgins JW; Ke AB; Zamek-Gliszczynski MJ
    Drug Metab Dispos; 2014 Nov; 42(11):1780-4. PubMed ID: 25106415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differences in Metformin and Thiamine Uptake between Human and Mouse Organic Cation Transporter 1: Structural Determinants and Potential Consequences for Intrahepatic Concentrations.
    Meyer MJ; Tuerkova A; Römer S; Wenzel C; Seitz T; Gaedcke J; Oswald S; Brockmöller J; Zdrazil B; Tzvetkov MV
    Drug Metab Dispos; 2020 Dec; 48(12):1380-1392. PubMed ID: 33037045
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein.
    Knop J; Misaka S; Singer K; Hoier E; Müller F; Glaeser H; König J; Fromm MF
    PLoS One; 2015; 10(10):e0139370. PubMed ID: 26426900
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.
    Bachmakov I; Glaeser H; Fromm MF; König J
    Diabetes; 2008 Jun; 57(6):1463-9. PubMed ID: 18314419
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Clearance and Liver Partitioning of OATP and OCT Substrates in Cynomolgus Monkeys.
    Morse BL; MacGuire JG; Marino AM; Zhao Y; Fox M; Zhang Y; Shen H; Griffith Humphreys W; Marathe P; Lai Y
    AAPS J; 2017 Nov; 19(6):1878-1889. PubMed ID: 29019117
    [TBL] [Abstract][Full Text] [Related]  

  • 9. OATP1B3 Expression and Function is Modulated by Coexpression with OCT1, OATP1B1, and NTCP.
    Zhang Y; Ruggiero M; Hagenbuch B
    Drug Metab Dispos; 2020 Aug; 48(8):622-630. PubMed ID: 32482756
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Organic Cation Transporter 1 Is Responsible for Hepatocellular Uptake of the Tyrosine Kinase Inhibitor Pazopanib.
    Ellawatty WEA; Masuo Y; Fujita KI; Yamazaki E; Ishida H; Arakawa H; Nakamichi N; Abdelwahed R; Sasaki Y; Kato Y
    Drug Metab Dispos; 2018 Jan; 46(1):33-40. PubMed ID: 29089306
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics.
    Wang L; Prasad B; Salphati L; Chu X; Gupta A; Hop CE; Evers R; Unadkat JD
    Drug Metab Dispos; 2015 Mar; 43(3):367-74. PubMed ID: 25534768
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics and hepatic uptake of eltrombopag, a novel platelet-increasing agent.
    Takeuchi K; Sugiura T; Umeda S; Matsubara K; Horikawa M; Nakamichi N; Silver DL; Ishiwata N; Kato Y
    Drug Metab Dispos; 2011 Jun; 39(6):1088-96. PubMed ID: 21422191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans.
    Liao M; Zhu Q; Zhu A; Gemski C; Ma B; Guan E; Li AP; Xiao G; Xia CQ
    Xenobiotica; 2019 Jul; 49(7):852-862. PubMed ID: 30132394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
    Li L; Song F; Tu M; Wang K; Zhao L; Wu X; Zhou H; Xia Z; Jiang H
    Int J Pharm; 2014 Apr; 465(1-2):5-10. PubMed ID: 24530383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.
    Kimura N; Masuda S; Tanihara Y; Ueo H; Okuda M; Katsura T; Inui K
    Drug Metab Pharmacokinet; 2005 Oct; 20(5):379-86. PubMed ID: 16272756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes.
    De Bruyn T; Ye ZW; Peeters A; Sahi J; Baes M; Augustijns PF; Annaert PP
    Eur J Pharm Sci; 2011 Jul; 43(4):297-307. PubMed ID: 21605667
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
    Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration.
    Tzvetkov MV; dos Santos Pereira JN; Meineke I; Saadatmand AR; Stingl JC; Brockmöller J
    Biochem Pharmacol; 2013 Sep; 86(5):666-78. PubMed ID: 23835420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhanced and Persistent Inhibition of Organic Cation Transporter 1 Activity by Preincubation of Cyclosporine A.
    Panfen E; Chen W; Zhang Y; Sinz M; Marathe P; Gan J; Shen H
    Drug Metab Dispos; 2019 Nov; 47(11):1352-1360. PubMed ID: 31427432
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Zhu P; Ye Z; Guo D; Xiong Z; Huang S; Guo J; Zhang W; Polli JE; Zhou H; Li Q; Shu Y
    Pharm Res; 2018 Oct; 35(12):243. PubMed ID: 30361780
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.