BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 33916289)

  • 1. Pathway-Directed Therapy in Multiple Myeloma.
    John L; Krauth MT; Podar K; Raab MS
    Cancers (Basel); 2021 Apr; 13(7):. PubMed ID: 33916289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer.
    Saini KS; Loi S; de Azambuja E; Metzger-Filho O; Saini ML; Ignatiadis M; Dancey JE; Piccart-Gebhart MJ
    Cancer Treat Rev; 2013 Dec; 39(8):935-46. PubMed ID: 23643661
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy.
    Li Q; Li Z; Luo T; Shi H
    Mol Biomed; 2022 Dec; 3(1):47. PubMed ID: 36539659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular signaling in multiple myeloma: association of RAS/RAF mutations and MEK/ERK pathway activation.
    Xu J; Pfarr N; Endris V; Mai EK; Md Hanafiah NH; Lehners N; Penzel R; Weichert W; Ho AD; Schirmacher P; Goldschmidt H; Andrulis M; Raab MS
    Oncogenesis; 2017 May; 6(5):e337. PubMed ID: 28504689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Emerging protein kinase inhibitors for the treatment of multiple myeloma.
    Lind J; Czernilofsky F; Vallet S; Podar K
    Expert Opin Emerg Drugs; 2019 Sep; 24(3):133-152. PubMed ID: 31327278
    [No Abstract]   [Full Text] [Related]  

  • 7. Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells.
    Suzuki R; Kikuchi S; Harada T; Mimura N; Minami J; Ohguchi H; Yoshida Y; Sagawa M; Gorgun G; Cirstea D; Cottini F; Jakubikova J; Tai YT; Chauhan D; Richardson PG; Munshi N; Ando K; Utsugi T; Hideshima T; Anderson KC
    PLoS One; 2015; 10(12):e0143847. PubMed ID: 26630652
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types.
    Britten CD
    Cancer Chemother Pharmacol; 2013 Jun; 71(6):1395-409. PubMed ID: 23443307
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sorafenib inhibits proliferation and invasion in desmoid-derived cells by targeting Ras/MEK/ERK and PI3K/Akt/mTOR pathways.
    Rosenberg L; Yoon CH; Sharma G; Bertagnolli MM; Cho NL
    Carcinogenesis; 2018 May; 39(5):681-688. PubMed ID: 29538717
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives.
    Asati V; Mahapatra DK; Bharti SK
    Eur J Med Chem; 2016 Feb; 109():314-41. PubMed ID: 26807863
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.
    Gedaly R; Angulo P; Hundley J; Daily MF; Chen C; Evers BM
    J Surg Res; 2012 Aug; 176(2):542-8. PubMed ID: 22261591
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relationships among
    Wan XB; Wang AQ; Cao J; Dong ZC; Li N; Yang S; Sun MM; Li Z; Luo SX
    World J Gastroenterol; 2019 Feb; 25(7):808-823. PubMed ID: 30809081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The comparison between dual inhibition of mTOR with MAPK and PI3K signaling pathways in KRAS mutant NSCLC cell lines.
    Dogan Turacli I; Ozkan AC; Ekmekci A
    Tumour Biol; 2015 Dec; 36(12):9339-45. PubMed ID: 26108998
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MEK inhibitors in oncology: a patent review (2015-Present).
    Mahapatra DK; Asati V; Bharti SK
    Expert Opin Ther Pat; 2017 Aug; 27(8):887-906. PubMed ID: 28594589
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual Inhibition of PI3K-AKT-mTOR- and RAF-MEK-ERK-signaling is synergistic in cholangiocarcinoma and reverses acquired resistance to MEK-inhibitors.
    Ewald F; Nörz D; Grottke A; Hofmann BT; Nashan B; Jücker M
    Invest New Drugs; 2014 Dec; 32(6):1144-54. PubMed ID: 25152244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Future targeting of the RAS/RAF/MEK/ERK signaling pathway in oncology: the example of melanoma].
    Favre G
    Bull Acad Natl Med; 2014 Feb; 198(2):321-36; discussion 337-8. PubMed ID: 26263707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting RAS-RAF-MEK-ERK signaling pathway in human cancer: Current status in clinical trials.
    Song Y; Bi Z; Liu Y; Qin F; Wei Y; Wei X
    Genes Dis; 2023 Jan; 10(1):76-88. PubMed ID: 37013062
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A phase 2 clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma.
    Giesen N; Chatterjee M; Scheid C; Poos AM; Besemer B; Miah K; Benner A; Becker N; Moehler T; Metzler I; Khandanpour C; Seidel-Glaetzer A; Trautmann-Grill K; Kortüm KM; Müller-Tidow C; Mechtersheimer G; Goeppert B; Stenzinger A; Weinhold N; Goldschmidt H; Weisel K; Raab MS
    Blood; 2023 Apr; 141(14):1685-1690. PubMed ID: 36608320
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Role of Activation of PI3K/AKT/mTOR and RAF/MEK/ERK Pathways in Aggressive Pituitary Adenomas-New Potential Therapeutic Approach-A Systematic Review.
    Derwich A; Sykutera M; Bromińska B; Rubiś B; Ruchała M; Sawicka-Gutaj N
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37446128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PI3K pathway activation mediates resistance to MEK inhibitors in KRAS mutant cancers.
    Wee S; Jagani Z; Xiang KX; Loo A; Dorsch M; Yao YM; Sellers WR; Lengauer C; Stegmeier F
    Cancer Res; 2009 May; 69(10):4286-93. PubMed ID: 19401449
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.