BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 33918210)

  • 1. Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration.
    Ebeling MC; Geng Z; Kapphahn RJ; Roehrich H; Montezuma SR; Dutton JR; Ferrington DA
    Cells; 2021 Apr; 10(4):. PubMed ID: 33918210
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway.
    Armento A; Schmidt TL; Sonntag I; Merle DA; Jarboui MA; Kilger E; Clark SJ; Ueffing M
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445430
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration.
    Lim RR; Shirali S; Rowlan J; Engel AL; Nazario M; Gonzalez K; Tong A; Neitz J; Neitz M; Chao JR
    Invest Ophthalmol Vis Sci; 2024 Apr; 65(4):43. PubMed ID: 38683564
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased retinal mtDNA damage in the CFH variant associated with age-related macular degeneration.
    Ferrington DA; Kapphahn RJ; Leary MM; Atilano SR; Terluk MR; Karunadharma P; Chen GK; Ratnapriya R; Swaroop A; Montezuma SR; Kenney MC
    Exp Eye Res; 2016 Apr; 145():269-277. PubMed ID: 26854823
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human complement factor H Y402H polymorphism causes an age-related macular degeneration phenotype and lipoprotein dysregulation in mice.
    Landowski M; Kelly U; Klingeborn M; Groelle M; Ding JD; Grigsby D; Bowes Rickman C
    Proc Natl Acad Sci U S A; 2019 Feb; 116(9):3703-3711. PubMed ID: 30808757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Repressed SIRT1/PGC-1α pathway and mitochondrial disintegration in iPSC-derived RPE disease model of age-related macular degeneration.
    Golestaneh N; Chu Y; Cheng SK; Cao H; Poliakov E; Berinstein DM
    J Transl Med; 2016 Dec; 14(1):344. PubMed ID: 27998274
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered transcriptome and disease-related phenotype emerge only after fibroblasts harvested from patients with age-related macular degeneration are differentiated into retinal pigment epithelium.
    Cai H; Gong J; ; Noggle S; Paull D; Rizzolo LJ; Del Priore LV; Fields MA
    Exp Eye Res; 2021 Jun; 207():108576. PubMed ID: 33895162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype.
    Radu RA; Hu J; Jiang Z; Bok D
    J Biol Chem; 2014 Mar; 289(13):9113-20. PubMed ID: 24550392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure.
    Hallam D; Collin J; Bojic S; Chichagova V; Buskin A; Xu Y; Lafage L; Otten EG; Anyfantis G; Mellough C; Przyborski S; Alharthi S; Korolchuk V; Lotery A; Saretzki G; McKibbin M; Armstrong L; Steel D; Kavanagh D; Lako M
    Stem Cells; 2017 Nov; 35(11):2305-2320. PubMed ID: 28913923
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells.
    Armento A; Honisch S; Panagiotakopoulou V; Sonntag I; Jacob A; Bolz S; Kilger E; Deleidi M; Clark S; Ueffing M
    Sci Rep; 2020 Jun; 10(1):10320. PubMed ID: 32587311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epithelial phenotype restoring drugs suppress macular degeneration phenotypes in an iPSC model.
    Sharma R; George A; Nimmagadda M; Ortolan D; Karla BS; Qureshy Z; Bose D; Dejene R; Liang G; Wan Q; Chang J; Jha BS; Memon O; Miyagishima KJ; Rising A; Lal M; Hanson E; King R; Campos MM; Ferrer M; Amaral J; McGaughey D; Bharti K
    Nat Commun; 2021 Dec; 12(1):7293. PubMed ID: 34911940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Systems genomics in age-related macular degeneration.
    den Hollander AI; Mullins RF; Orozco LD; Voigt AP; Chen HH; Strunz T; Grassmann F; Haines JL; Kuiper JJW; Tumminia SJ; Allikmets R; Hageman GS; Stambolian D; Klaver CCW; Boeke JD; Chen H; Honigberg L; Katti S; Frazer KA; Weber BHF; Gorin MB
    Exp Eye Res; 2022 Dec; 225():109248. PubMed ID: 36108770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Noncanonical Role of Complement Factor H in Retinal Pigment Epithelium (RPE) Cells and Implications for Age-Related Macular Degeneration (AMD).
    Armento A; Merle DA; Ueffing M
    Adv Exp Med Biol; 2023; 1415():9-13. PubMed ID: 37440007
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effect of photo-oxidative stress and inflammatory cytokine on complement factor H expression in retinal pigment epithelial cells.
    Lau LI; Chiou SH; Liu CJ; Yen MY; Wei YH
    Invest Ophthalmol Vis Sci; 2011 Aug; 52(9):6832-41. PubMed ID: 21743006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions.
    Gong J; Cai H; ; Noggle S; Paull D; Rizzolo LJ; Del Priore LV; Fields MA
    Stem Cells Transl Med; 2020 Mar; 9(3):364-376. PubMed ID: 31840941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inflammasome Activation in Retinal Pigment Epithelium from Human Donors with Age-Related Macular Degeneration.
    Ebeling MC; Fisher CR; Kapphahn RJ; Stahl MR; Shen S; Qu J; Montezuma SR; Ferrington DA
    Cells; 2022 Jun; 11(13):. PubMed ID: 35805159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration.
    Krilis M; Qi M; Qi J; Wong JWH; Guymer R; Liew G; Hunyor AP; Madigan M; McCluskey P; Weaver J; Krilis SA; Giannakopoulos B
    Free Radic Biol Med; 2018 Dec; 129():237-246. PubMed ID: 30253188
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondria-dependent phase separation of disease-relevant proteins drives pathological features of age-related macular degeneration.
    La Cunza N; Tan LX; Thamban T; Germer CJ; Rathnasamy G; Toops KA; Lakkaraju A
    JCI Insight; 2021 May; 6(9):. PubMed ID: 33822768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model.
    Armento A; Murali A; Marzi J; Almansa-Garcia AC; Arango-Gonzalez B; Kilger E; Clark SJ; Schenke-Layland K; Ramlogan-Steel CA; Steel JC; Ueffing M
    Biomolecules; 2021 Nov; 11(11):. PubMed ID: 34827622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Association between Y402H, E318D and R102G polymorphisms of complement proteins genes and the response to intravitreal anti-VEGF treatment in patients with neovascular age-related macular degeneration].
    Kubicka-Trząska A; Karska-Basta I; Kobylarz J; Dziedzina S; Sanak M; Romanowska-Dixon B
    Klin Oczna; 2016; 118(2):114-21. PubMed ID: 29912491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.